gamma-Glutamyltransferase

"gamma-Glutamyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An enzyme, sometimes called GGT, with a key role in the synthesis and degradation of GLUTATHIONE; (GSH, a tripeptide that protects cells from many toxins). It catalyzes the transfer of the gamma-glutamyl moiety to an acceptor amino acid.

Descriptor ID	D005723
MeSH Number(s)	D08.811.913.050.200.500
Concept/Terms	gamma-Glutamyltransferase gamma-Glutamyltransferase gamma Glutamyltransferase GGTP gammaglutamyltransferase Glutamyl Transpeptidase Transpeptidase, Glutamyl gamma-Glutamyl Transpeptidase Transpeptidase, gamma-Glutamyl gamma Glutamyl Transpeptidase

Below are MeSH descriptors whose meaning is more general than "gamma-Glutamyltransferase".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Acyltransferases [D08.811.913.050]
Aminoacyltransferases [D08.811.913.050.200]
gamma-Glutamyltransferase [D08.811.913.050.200.500]

Below are MeSH descriptors whose meaning is related to "gamma-Glutamyltransferase".

Below are MeSH descriptors whose meaning is more specific than "gamma-Glutamyltransferase".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "gamma-Glutamyltransferase" by people in this website by year, and whether "gamma-Glutamyltransferase" was a major or minor topic of these publications.

Bar chart showing 5 publications over 5 distinct years, with a maximum of 1 publications in 2007 and 2012 and 2015 and 2020 and 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2007	0	1	1
2012	1	0	1
2015	0	1	1
2020	0	1	1
2021	0	1	1

Below are the most recent publications written about "gamma-Glutamyltransferase" by people in Profiles.

Martinez M, Perito ER, Valentino P, Mack CL, Aumar M, Broderick A, Draijer LG, Fagundes EDT, Furuya KN, Gupta N, Horslen S, Jonas MM, Kamath BM, Kerkar N, Kim KM, Kolho KL, Koot BGP, Laborda TJ, Lee CK, Loomes KM, Miloh T, Mogul D, Mohammed S, Ovchinsky N, Rao G, Ricciuto A, Rodrigues Ferreira A, Schwarz KB, Smolka V, Tanaka A, Tessier MEM, Venkat VL, Vitola BE, Woynarowski M, Zerofsky M, Deneau MR. Recurrence of Primary Sclerosing Cholangitis After Liver Transplant in Children: An International Observational Study. Hepatology. 2021 10; 74(4):2047-2057.

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Deneau MR, Mack C, Perito ER, Ricciuto A, Valentino PL, Amin M, Amir AZ, Aumar M, Auth M, Broderick A, DiGuglielmo M, Draijer LG, Tavares Fagundes ED, El-Matary W, Ferrari F, Furuya KN, Gupta N, Hochberg JT, Homan M, Horslen S, Iorio R, Jensen MK, Jonas MM, Kamath BM, Kerkar N, Kim KM, Kolho KL, Koot BGP, Laborda TJ, Lee CK, Loomes KM, Martinez M, Miethke A, Miloh T, Mogul D, Mohammad S, Mohan P, Moroz S, Ovchinsky N, Palle S, Papadopoulou A, Rao G, Rodrigues Ferreira A, Sathya P, Schwarz KB, Shah U, Shteyer E, Singh R, Smolka V, Soufi N, Tanaka A, Varier R, Vitola B, Woynarowski M, Zerofsky M, Zizzo A, Guthery SL. The Sclerosing Cholangitis Outcomes in Pediatrics (SCOPE) Index: A Prognostic Tool for Children. Hepatology. 2021 03; 73(3):1074-1087.

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Williams KH, Sullivan DR, Nicholson GC, George J, Jenkins AJ, Januszewski AS, Gebski VJ, Manning P, Tan YM, Donoghoe MW, Ehnholm C, Young S, O'Brien R, Buizen L, Twigg SM, Keech AC. Opposite associations between alanine aminotransferase and ?-glutamyl transferase levels and all-cause mortality in type 2 diabetes: Analysis of the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. Metabolism. 2016 May; 65(5):783-793.

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Hann HW, Wan S, Myers RE, Hann RS, Xing J, Chen B, Yang H. Comprehensive analysis of common serum liver enzymes as prospective predictors of hepatocellular carcinoma in HBV patients. PLoS One. 2012; 7(10):e47687.

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Sass DA, Chadalavada R, Virji MA. Unexplained isolated elevation in serum aspartate aminotransferase: think macro! Am J Med. 2007 Sep; 120(9):e5-6.

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Campling BG, Baer K, Baker HM, Lam YM, Cole SP. Do glutathione and related enzymes play a role in drug resistance in small cell lung cancer cell lines? Br J Cancer. 1993 Aug; 68(2):327-35.

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Lan?a AJ, Israel Y. Histochemical demonstration of sinusoidal gamma-glutamyltransferase activity by substrate protection fixation: comparative studies in rat and guinea pig liver. Hepatology. 1991 Nov; 14(5):857-63.

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Chiba M, Aldaz CM, Conti CJ, Klein-Szanto AJ. Metastatic potential of mouse skin carcinomas produced by different protocols of chemical carcinogenesis. Invasion Metastasis. 1991; 11(5):288-96.

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Speisky H, Israel Y. Gamma-glutamyl transferase ectoactivity in the intact rat liver: effect of chronic alcohol consumption. Alcohol. 1990 Jul-Aug; 7(4):339-47.

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Speisky H, Shackel N, Varghese G, Wade D, Israel Y. Role of hepatic gamma-glutamyltransferase in the degradation of circulating glutathione: studies in the intact guinea pig perfused liver. Hepatology. 1990 May; 11(5):843-9.

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