Cyclic GMP

"Cyclic GMP" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Guanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed)

Descriptor ID	D006152
MeSH Number(s)	D03.633.100.759.646.454.160 D13.695.462.275 D13.695.667.454.160 D13.695.827.426.160
Concept/Terms	Cyclic GMP Cyclic GMP GMP, Cyclic Guanosine Cyclic Monophosphate Cyclic Monophosphate, Guanosine Monophosphate, Guanosine Cyclic Guanosine Cyclic 3',5'-Monophosphate 3',5'-Monophosphate, Guanosine Cyclic Cyclic 3',5'-Monophosphate, Guanosine Guanosine Cyclic 3,5 Monophosphate Guanosine Cyclic-3',5'-Monophosphate Cyclic-3',5'-Monophosphate, Guanosine Guanosine Cyclic 3',5' Monophosphate

Below are MeSH descriptors whose meaning is more general than "Cyclic GMP".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Purines [D03.633.100.759]
Purine Nucleotides [D03.633.100.759.646]
Guanine Nucleotides [D03.633.100.759.646.454]
Cyclic GMP [D03.633.100.759.646.454.160]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Nucleotides [D13.695]
Nucleotides, Cyclic [D13.695.462]
Cyclic GMP [D13.695.462.275]
Purine Nucleotides [D13.695.667]
Guanine Nucleotides [D13.695.667.454]
Cyclic GMP [D13.695.667.454.160]
Ribonucleotides [D13.695.827]
Guanine Nucleotides [D13.695.827.426]
Cyclic GMP [D13.695.827.426.160]

Below are MeSH descriptors whose meaning is related to "Cyclic GMP".

Below are MeSH descriptors whose meaning is more specific than "Cyclic GMP".

Cyclic GMP
Dibutyryl Cyclic GMP

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cyclic GMP" by people in this website by year, and whether "Cyclic GMP" was a major or minor topic of these publications.

Bar chart showing 45 publications over 22 distinct years, with a maximum of 4 publications in 2002 and 2003

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
1999	1	1	2
2000	2	0	2
2001	0	2	2
2002	1	3	4
2003	1	3	4
2004	2	1	3
2005	1	2	3
2006	0	3	3
2008	0	1	1
2009	1	1	2
2010	0	1	1
2011	1	2	3
2012	1	0	1
2013	1	1	2
2014	0	1	1
2016	0	3	3
2017	0	2	2
2018	0	1	1
2019	0	2	2
2021	0	1	1
2023	0	1	1

Below are the most recent publications written about "Cyclic GMP" by people in Profiles.

Barton JR, Londregan AK, Alexander TD, Entezari AA, Bar-Ad S, Cheng L, Lepore AC, Snook AE, Covarrubias M, Waldman SA. Intestinal neuropod cell GUCY2C regulates visceral pain. J Clin Invest. 2023 02 15; 133(4).

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Weinberg DS, Foster NR, Della'Zanna G, McMurray RP, Kraft WK, Pallotto A, Kastenberg DM, Katz LC, Henry CH, Moleski SM, Limburg PJ, Waldman SA. Phase I double-blind, placebo-controlled trial of dolcanatide (SP-333) 27 mg to explore colorectal bioactivity in healthy volunteers. Cancer Biol Ther. 2021 12 02; 22(10-12):544-553.

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Chen T, Lin R, Avula L, Sarker R, Yang J, Cha B, Tse CM, McNamara G, Seidler U, Waldman S, Snook A, Bijvelds MJC, de Jonge HR, Li X, Donowitz M. NHERF3 is necessary for Escherichia coli heat-stable enterotoxin-induced inhibition of NHE3: differences in signaling in mouse small intestine and Caco-2 cells. Am J Physiol Cell Physiol. 2019 10 01; 317(4):C737-C748.

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Heindl JE, Crosby D, Brar S, Pinto JF, Singletary T, Merenich D, Eagan JL, Buechlein AM, Bruger EL, Waters CM, Fuqua C. Reciprocal control of motility and biofilm formation by the PdhS2 two-component sensor kinase of Agrobacterium tumefaciens. Microbiology (Reading). 2019 02; 165(2):146-162.

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Donda K, Zambrano R, Moon Y, Percival J, Vaidya R, Dapaah-Siakwan F, Luo S, Duncan MR, Bao Y, Wang L, Qin L, Benny M, Young K, Wu S. Riociguat prevents hyperoxia-induced lung injury and pulmonary hypertension in neonatal rats without effects on long bone growth. PLoS One. 2018; 13(7):e0199927.

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Weinberg DS, Lin JE, Foster NR, Della'Zanna G, Umar A, Seisler D, Kraft WK, Kastenberg DM, Katz LC, Limburg PJ, Waldman SA. Bioactivity of Oral Linaclotide in Human Colorectum for Cancer Chemoprevention. Cancer Prev Res (Phila). 2017 Jun; 10(6):345-354.

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Eto M, Kitazawa T. Diversity and plasticity in signaling pathways that regulate smooth muscle responsiveness: Paradigms and paradoxes for the myosin phosphatase, the master regulator of smooth muscle contraction. J Smooth Muscle Res. 2017; 53(0):1-19.

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Pattison AM, Merlino DJ, Blomain ES, Waldman SA. Guanylyl cyclase C signaling axis and colon cancer prevention. World J Gastroenterol. 2016 Sep 28; 22(36):8070-7.

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Pattison AM, Blomain ES, Merlino DJ, Wang F, Crissey MA, Kraft CL, Rappaport JA, Snook AE, Lynch JP, Waldman SA. Intestinal Enteroids Model Guanylate Cyclase C-Dependent Secretion Induced by Heat-Stable Enterotoxins. Infect Immun. 2016 10; 84(10):3083-91.

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Waldman SA. Editorial (Thematic Issue: Ferid Murad, at 80: A Legacy of Science, Medicine, and Mentorship). Curr Med Chem. 2016; 23(24):2556-2558.

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