"Hirschsprung Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Congenital MEGACOLON resulting from the absence of ganglion cells (aganglionosis) in a distal segment of the LARGE INTESTINE. The aganglionic segment is permanently contracted thus causing dilatation proximal to it. In most cases, the aganglionic segment is within the RECTUM and SIGMOID COLON.
| Descriptor ID |
D006627
|
| MeSH Number(s) |
C06.198.439 C06.405.469.158.701.439 C16.131.314.439
|
| Concept/Terms |
Hirschsprung Disease- Hirschsprung Disease
- Disease, Hirschsprung
- Megacolon, Congenital
- Hirschsprung's Disease
- Disease, Hirschsprung's
- Hirschsprungs Disease
- Megacolon, Aganglionic
- Aganglionic Megacolon
- Congenital Megacolon
Aganglionosis, Colonic- Aganglionosis, Colonic
- Colonic Aganglionosis
- Total Colonic Aganglionosis
- Aganglionosis, Total Colonic
|
Below are MeSH descriptors whose meaning is more general than "Hirschsprung Disease".
Below are MeSH descriptors whose meaning is more specific than "Hirschsprung Disease".
This graph shows the total number of publications written about "Hirschsprung Disease" by people in this website by year, and whether "Hirschsprung Disease" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2019 | 2 | 0 | 2 |
| 2020 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Hirschsprung Disease" by people in Profiles.
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Srinivas S, Shalash B, Knaus M, Bergus KC, Pruitt LC, Brock G, Thomas J, Minneci PC, Deans K, Wood RJ. Patient-Reported Experience in Colorectal Disease is Predicted by Cleanliness. J Pediatr Surg. 2024 Oct; 59(10):161572.
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Gil LA, Asti L, Apfeld JC, Sebasti?o YV, Deans KJ, Minneci PC. Perioperative outcomes in minimally-invasive versus open surgery in infants undergoing repair of congenital anomalies. J Pediatr Surg. 2022 Dec; 57(12):755-762.
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Apfeld JC, Wood RJ, Halleran DR, Deans KJ, Minneci PC, Cooper JN. Relationships Between Hospital and Surgeon Operative Volumes and Surgical Outcomes in Hirschsprung's Disease. J Surg Res. 2021 01; 257:379-388.
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Newland JJ, Dukleska K, Cowan S, Yeo CJ, Tholey R. Dr. Orvar Swenson and the Pull-Through. Am Surg. 2019 Dec 01; 85(12):1311-1313.
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Halleran DR, Ahmad H, Maloof E, Paradiso M, Lehmkuhl H, Minneci PC, Levitt MA, Wood RJ. Does Hirschsprung-Associated Enterocolitis Differ in Children With and Without Down Syndrome? J Surg Res. 2020 01; 245:564-568.
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Lane VA, Nacion KM, Cooper JN, Levitt MA, Deans KJ, Minneci PC. Determinants of quality of life in children with colorectal diseases. J Pediatr Surg. 2016 Nov; 51(11):1843-1850.
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Sulkowski JP, Cooper JN, Congeni A, Pearson EG, Nwomeh BC, Doolin EJ, Blakely ML, Minneci PC, Deans KJ. Single-stage versus multi-stage pull-through for Hirschsprung's disease: practice trends and outcomes in infants. J Pediatr Surg. 2014 Nov; 49(11):1619-25.
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Manthey AL, Lachke SA, FitzGerald PG, Mason RW, Scheiblin DA, McDonald JH, Duncan MK. Loss of Sip1 leads to migration defects and retention of ectodermal markers during lens development. Mech Dev. 2014 Feb; 131:86-110.
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Proujansky R. Molecular cause of Hirschsprung disease. J Pediatr. 1996 May; 128(5 Pt 1):720.
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Pavan WJ, Liddell RA, Wright A, Thibaudeau G, Matteson PG, McHugh KM, Siracusa LD. A high-resolution linkage map of the lethal spotting locus: a mouse model for Hirschsprung disease. Mamm Genome. 1995 Jan; 6(1):1-7.