Hydroxychloroquine

"Hydroxychloroquine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa. It inhibits plasmodial heme polymerase. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p970)

Descriptor ID	D006886
MeSH Number(s)	D03.633.100.810.050.180.350
Concept/Terms	Hydroxychloroquine Hydroxychloroquine Oxychlorochin Oxychloroquine Hydroxychlorochin Plaquenil Plaquenil Hydroxychloroquine Sulfate Hydroxychloroquine Sulfate Hydroxychloroquine Sulfate (1:1) Salt

Below are MeSH descriptors whose meaning is more general than "Hydroxychloroquine".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Quinolines [D03.633.100.810]
Aminoquinolines [D03.633.100.810.050]
Chloroquine [D03.633.100.810.050.180]
Hydroxychloroquine [D03.633.100.810.050.180.350]

Below are MeSH descriptors whose meaning is related to "Hydroxychloroquine".

Below are MeSH descriptors whose meaning is more specific than "Hydroxychloroquine".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Hydroxychloroquine" by people in this website by year, and whether "Hydroxychloroquine" was a major or minor topic of these publications.

Bar chart showing 14 publications over 8 distinct years, with a maximum of 6 publications in 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2003	1	0	1
2004	1	0	1
2005	0	1	1
2007	1	0	1
2018	0	1	1
2020	1	5	6
2021	1	1	2

Below are the most recent publications written about "Hydroxychloroquine" by people in Profiles.

Liu HH, Ezekowitz MD, Columbo M, Khan O, Martin J, Spahr J, Yaron D, Cushinotto L, Kapelusznik L. The future is now: our experience starting a remote clinical trial during the beginning of the COVID-19 pandemic. Trials. 2021 Sep 07; 22(1):603.

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Coppock D, Baram M, Chang AM, Henwood P, Kubey A, Summer R, Zurlo J, Li M, Hess B. COVID-19 treatment combinations and associations with mortality in a large multi-site healthcare system. PLoS One. 2021; 16(6):e0252591.

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Roomi S, Ullah W, Ahmed F, Farooq S, Sadiq U, Chohan A, Jafar M, Saddique M, Khanal S, Watson R, Boigon M. Efficacy of Hydroxychloroquine and Tocilizumab in Patients With COVID-19: Single-Center Retrospective Chart Review. J Med Internet Res. 2020 09 01; 22(9):e21758.

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Hiedra R, Lo KB, Elbashabsheh M, Gul F, Wright RM, Albano J, Azmaiparashvili Z, Patarroyo Aponte G. The use of IV vitamin C for patients with COVID-19: a case series. Expert Rev Anti Infect Ther. 2020 Dec; 18(12):1259-1261.

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Nasir N, Farooqi J, Mahmood SF, Jabeen K. COVID-19-associated pulmonary aspergillosis (CAPA) in patients admitted with severe COVID-19 pneumonia: An observational study from Pakistan. Mycoses. 2020 Aug; 63(8):766-770.

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Salacup G, Lo KB, Gul F, Peterson E, De Joy R, Bhargav R, Pelayo J, Albano J, Azmaiparashvili Z, Benzaquen S, Patarroyo-Aponte G, Rangaswami J. Characteristics and clinical outcomes of COVID-19 patients in an underserved-inner city population: A single tertiary center cohort. J Med Virol. 2021 01; 93(1):416-423.

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Abena PM, Decloedt EH, Bottieau E, Suleman F, Adejumo P, Sam-Agudu NA, Muyembe TamFum JJ, Seydi M, Eholie SP, Mills EJ, Kallay O, Zumla A, Nachega JB. Chloroquine and Hydroxychloroquine for the Prevention or Treatment of COVID-19 in Africa: Caution for Inappropriate Off-label Use in Healthcare Settings. Am J Trop Med Hyg. 2020 06; 102(6):1184-1188.

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Zeh HJ, Bahary N, Boone BA, Singhi AD, Miller-Ocuin JL, Normolle DP, Zureikat AH, Hogg ME, Bartlett DL, Lee KK, Tsung A, Marsh JW, Murthy P, Tang D, Seiser N, Amaravadi RK, Espina V, Liotta L, Lotze MT. A Randomized Phase II Preoperative Study of Autophagy Inhibition with High-Dose Hydroxychloroquine and Gemcitabine/Nab-Paclitaxel in Pancreatic Cancer Patients. Clin Cancer Res. 2020 07 01; 26(13):3126-3134.

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Boone BA, Murthy P, Miller-Ocuin J, Doerfler WR, Ellis JT, Liang X, Ross MA, Wallace CT, Sperry JL, Lotze MT, Neal MD, Zeh HJ. Chloroquine reduces hypercoagulability in pancreatic cancer through inhibition of neutrophil extracellular traps. BMC Cancer. 2018 Jun 22; 18(1):678.

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Rodriguez-Padilla JA, Hedges TR, Monson B, Srinivasan V, Wojtkowski M, Reichel E, Duker JS, Schuman JS, Fujimoto JG. High-speed ultra-high-resolution optical coherence tomography findings in hydroxychloroquine retinopathy. Arch Ophthalmol. 2007 Jun; 125(6):775-80.

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