Hydroxymethylglutaryl CoA Reductases
"Hydroxymethylglutaryl CoA Reductases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyze the reversible reduction of alpha-carboxyl group of 3-hydroxy-3-methylglutaryl-coenzyme A to yield MEVALONIC ACID.
| Descriptor ID |
D006903
|
| MeSH Number(s) |
D08.811.682.047.820.150.415
|
| Concept/Terms |
Hydroxymethylglutaryl CoA Reductases- Hydroxymethylglutaryl CoA Reductases
- Hydroxymethylglutaryl CoA Reductase
- HMG CoA Reductases
- 3-Hydroxy-3-methylglutaryl CoA Reductase
- 3 Hydroxy 3 methylglutaryl CoA Reductase
- CoA Reductase, 3-Hydroxy-3-methylglutaryl
- Reductase, 3-Hydroxy-3-methylglutaryl CoA
- HMG CoA Reductase
|
Below are MeSH descriptors whose meaning is more general than "Hydroxymethylglutaryl CoA Reductases".
Below are MeSH descriptors whose meaning is more specific than "Hydroxymethylglutaryl CoA Reductases".
This graph shows the total number of publications written about "Hydroxymethylglutaryl CoA Reductases" by people in this website by year, and whether "Hydroxymethylglutaryl CoA Reductases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hydroxymethylglutaryl CoA Reductases" by people in Profiles.
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Dalakas MC. Myositis: Are autoantibodies pathogenic in necrotizing myopathy? Nat Rev Rheumatol. 2018 05; 14(5):251-252.
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Yeganeh B, Wiechec E, Ande SR, Sharma P, Moghadam AR, Post M, Freed DH, Hashemi M, Shojaei S, Zeki AA, Ghavami S. Targeting the mevalonate cascade as a new therapeutic approach in heart disease, cancer and pulmonary disease. Pharmacol Ther. 2014 Jul; 143(1):87-110.
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Rattan S. 3-Hydroxymethyl coenzyme A reductase inhibition attenuates spontaneous smooth muscle tone via RhoA/ROCK pathway regulated by RhoA prenylation. Am J Physiol Gastrointest Liver Physiol. 2010 Jun; 298(6):G962-9.
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Ma YB, Li BY, Gao HQ, Yao M, Koch WJ, Eckhart AD, Zhou RH. [Activation of sterol regulatory element binding protein and its involvement in endothelial cell migration]. Zhonghua Bing Li Xue Za Zhi. 2009 Jan; 38(1):50-4.
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Pan HY, DeVault AR, Wang-Iverson D, Ivashkiv E, Swanson BN, Sugerman AA. Comparative pharmacokinetics and pharmacodynamics of pravastatin and lovastatin. J Clin Pharmacol. 1990 Dec; 30(12):1128-35.