"Ivermectin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mixture of mostly avermectin H2B1a (RN 71827-03-7) with some avermectin H2B1b (RN 70209-81-3), which are macrolides from STREPTOMYCES avermitilis. It binds glutamate-gated chloride channel to cause increased permeability and hyperpolarization of nerve and muscle cells. It also interacts with other CHLORIDE CHANNELS. It is a broad spectrum antiparasitic that is active against microfilariae of ONCHOCERCA VOLVULUS but not the adult form.
| Descriptor ID |
D007559
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| MeSH Number(s) |
D02.540.576.500.997
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Ivermectin".
Below are MeSH descriptors whose meaning is more specific than "Ivermectin".
This graph shows the total number of publications written about "Ivermectin" by people in this website by year, and whether "Ivermectin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 2 | 0 | 2 |
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Below are the most recent publications written about "Ivermectin" by people in Profiles.
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Choksi TT, Madison G, Dar T, Asif M, Fleming K, Clarke L, Danilewitz M, Hennawy R. Multiorgan Dysfunction Syndrome from Strongyloides stercoralis Hyperinfection in a Patient with Human T-Cell Lymphotropic Virus-1 Coinfection After Initiation of Ivermectin Treatment. Am J Trop Med Hyg. 2016 Oct 05; 95(4):864-867.
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Aru RG, Chilcutt BM, Butt S, deShazo RD. Novel Findings in HIV, Immune Reconstitution Disease and Strongyloides stercoralis Infection. Am J Med Sci. 2017 06; 353(6):593-596.
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Nolan TJ, Rotman HL, Bhopale VM, Schad GA, Abraham D. Immunity to a challenge infection of Strongyloides stercoralis third-stage larvae in the jird. Parasite Immunol. 1995 Nov; 17(11):599-604.
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Grieve RB, Abraham D, Mika-Grieve M, Seibert BP. Induction of protective immunity in dogs to infection with Dirofilaria immitis using chemically-abbreviated infections. Am J Trop Med Hyg. 1988 Oct; 39(4):373-9.