Lymphocyte Culture Test, Mixed
"Lymphocyte Culture Test, Mixed" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Measure of histocompatibility at the HL-A locus. Peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several days. Lymphocytes from incompatible individuals will stimulate each other to proliferate significantly (measured by tritiated thymidine uptake) whereas those from compatible individuals will not. In the one-way MLC test, the lymphocytes from one of the individuals are inactivated (usually by treatment with MITOMYCIN or radiation) thereby allowing only the untreated remaining population of cells to proliferate in response to foreign histocompatibility antigens.
| Descriptor ID |
D007959
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| MeSH Number(s) |
E01.370.225.812.385.475 E05.200.812.385.475 E05.478.594.385.429
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| Concept/Terms |
Lymphocyte Culture Test, Mixed- Lymphocyte Culture Test, Mixed
- Leukocyte Culture Test, Mixed
- Mixed Lymphocyte Reaction
- Lymphocyte Reaction, Mixed
- Lymphocyte Reactions, Mixed
- Mixed Lymphocyte Reactions
- Mixed Leukocyte Reaction
- Leukocyte Reaction, Mixed
- Leukocyte Reactions, Mixed
- Mixed Leukocyte Reactions
- Mixed Leukocyte Culture Test
- Mixed Lymphocyte Culture Test
|
Below are MeSH descriptors whose meaning is more general than "Lymphocyte Culture Test, Mixed".
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This graph shows the total number of publications written about "Lymphocyte Culture Test, Mixed" by people in this website by year, and whether "Lymphocyte Culture Test, Mixed" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lymphocyte Culture Test, Mixed" by people in Profiles.
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Metz R, Smith C, DuHadaway JB, Chandler P, Baban B, Merlo LM, Pigott E, Keough MP, Rust S, Mellor AL, Mandik-Nayak L, Muller AJ, Prendergast GC. IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation. Int Immunol. 2014 Jul; 26(7):357-67.
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Bamboat ZM, Stableford JA, Plitas G, Burt BM, Nguyen HM, Welles AP, Gonen M, Young JW, DeMatteo RP. Human liver dendritic cells promote T cell hyporesponsiveness. J Immunol. 2009 Feb 15; 182(4):1901-11.
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Yamazaki S, Patel M, Harper A, Bonito A, Fukuyama H, Pack M, Tarbell KV, Talmor M, Ravetch JV, Inaba K, Steinman RM. Effective expansion of alloantigen-specific Foxp3+ CD25+ CD4+ regulatory T cells by dendritic cells during the mixed leukocyte reaction. Proc Natl Acad Sci U S A. 2006 Feb 21; 103(8):2758-63.
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Keever CA, Abu-Hajir M, Graf W, McFadden P, Prichard P, O'Brien J, Flomenberg N. Characterization of the alloreactivity and anti-leukemia reactivity of cord blood mononuclear cells. Bone Marrow Transplant. 1995 Mar; 15(3):407-19.
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Iwata M, Yagihashi A, Roat MI, Zeevi A, Iwaki Y, Thoft RA. Human leukocyte antigen-class II-positive human corneal epithelial cells activate allogeneic T cells. Invest Ophthalmol Vis Sci. 1994 Nov; 35(12):3991-4000.
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Cowchock FS, Smith JB, David S, Scher J, Batzer F, Corson S. Paternal mononuclear cell immunization therapy for repeated miscarriage: predictive variables for pregnancy success. Am J Reprod Immunol. 1990 Jan-Feb; 22(1-2):12-7.
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Keever CA, Flomenberg N, Small T, Brochstein J, Collins N, Young-Yang S, Insel R, Dupont B, O'Reilly RJ. Loss of tolerance associated with disappearance of B cells in a patient sequentially transplanted with paternal and maternal bone marrow for the treatment of severe combined immunodeficiency disease. Hum Immunol. 1989 Sep; 26(1):27-38.
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Bocchieri MH, Sabol JL, O'Neill DK. Age-related decline in cell-mediated immunity in the C58 leukemic mouse strain. Gerontology. 1988; 34(5-6):221-30.
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Eckels DD, Zeevi A, Beatty PG, Flomenberg N, Goyert S, Knowles RW, Mickelson E, Nepom GT, Parham P, Pawelec G, et al. ASHI Workshop Summary Report of the Science and Education Subcommittee: structural and functional relationships of human class II MHC molecules. Hum Immunol. 1986 Jan; 15(1):68-74.
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Hutchins MR, Slease RB, Murray JL, Gawith KE, Grozea PN. Abnormal immunoregulation in remission Hodgkin disease. Am J Hematol. 1985 Oct; 20(2):119-28.