Ligands

"Ligands" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A molecule that binds to another molecule, used especially to refer to a small molecule that binds specifically to a larger molecule, e.g., an antigen binding to an antibody, a hormone or neurotransmitter binding to a receptor, or a substrate or allosteric effector binding to an enzyme. Ligands are also molecules that donate or accept a pair of electrons to form a coordinate covalent bond with the central metal atom of a coordination complex. (From Dorland, 27th ed)

Descriptor ID	D008024
MeSH Number(s)	D27.720.470.480
Concept/Terms	Ligands Ligands

Below are MeSH descriptors whose meaning is more general than "Ligands".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Specialty Uses of Chemicals [D27.720]
Laboratory Chemicals [D27.720.470]
Ligands [D27.720.470.480]

Below are MeSH descriptors whose meaning is related to "Ligands".

Below are MeSH descriptors whose meaning is more specific than "Ligands".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Ligands" by people in this website by year, and whether "Ligands" was a major or minor topic of these publications.

Bar chart showing 150 publications over 29 distinct years, with a maximum of 11 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	3	3
1997	0	6	6
1998	0	2	2
1999	0	3	3
2000	0	5	5
2001	0	4	4
2002	0	4	4
2003	1	7	8
2004	0	5	5
2005	0	9	9
2006	0	6	6
2007	0	8	8
2008	0	2	2
2009	0	7	7
2010	0	7	7
2011	0	9	9
2012	0	6	6
2013	1	10	11
2014	1	6	7
2015	0	5	5
2016	0	4	4
2017	1	5	6
2018	1	4	5
2019	0	1	1
2020	0	1	1
2021	0	6	6
2022	0	1	1
2023	0	3	3
2024	0	6	6

Below are the most recent publications written about "Ligands" by people in Profiles.

Alugupalli KR. Characterization of Turbo, a TLR Ligand-based Adjuvant for Glycoconjugate Vaccines. Immunohorizons. 2024 08 01; 8(8):527-537.

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Kalabekova R, Quinn CM, Movellan KT, Gronenborn AM, Akke M, Polenova T. 19F Fast Magic-Angle Spinning NMR Spectroscopy on Microcrystalline Complexes of Fluorinated Ligands and the Carbohydrate Recognition Domain of Galectin-3. Biochemistry. 2024 09 03; 63(17):2207-2216.

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Alugupalli KR. A TLR4 ligand-based adjuvant for promoting the immunogenicity of typhoid subunit vaccines. Front Immunol. 2024; 15:1383476.

View in: PubMed
Alugupalli KR. Monophosphoryl Lipid A-based Adjuvant to Promote the Immunogenicity of Multivalent Meningococcal Polysaccharide Conjugate Vaccines. Immunohorizons. 2024 04 01; 8(4):317-325.

View in: PubMed
Battaglin F, Baca Y, Millstein J, Yang Y, Xiu J, Arai H, Wang J, Ou FS, Innocenti F, Mumenthaler SM, Jayachandran P, Kawanishi N, Lenz A, Soni S, Algaze S, Zhang W, Khoukaz T, Roussos Torres E, Seeber A, Abraham JP, Lou E, Philip PA, Weinberg BA, Shields AF, Goldberg RM, Marshall JL, Venook AP, Korn WM, Lenz HJ. CCR5 and CCL5 gene expression in colorectal cancer: comprehensive profiling and clinical value. J Immunother Cancer. 2024 01 11; 12(1).

View in: PubMed
Alugupalli KR. TLR4 Ligands in Typhoid Vi Polysaccharide Subunit Vaccines Contribute to Immunogenicity. Immunohorizons. 2024 01 01; 8(1):29-34.

View in: PubMed
Philips R, Alnemri A, Amin D, Patel J, Topf MC, Johnson JM, BarAd V, Axelrod R, Argiris A, Fundakowski C, Luginbuhl AJ, Cognetti DM, Curry JM. Effect of preoperative programmed death-1 or programmed death ligand-1 immune check point inhibition on complications after surgery for primary head and neck cancer. Cancer. 2024 03 15; 130(6):863-875.

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Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA, Beuve A, Brouckaert P, Bryant C, Burnett JC, Farndale RW, Friebe A, Garthwaite J, Hobbs AJ, Jarvis GE, Koesling D, Kuhn M, MacEwan D, Monie TP, Potter LR, Russwurm M, Schmidt HHHW, Stasch JP, Waldman SA. The Concise Guide to PHARMACOLOGY 2023/24: Catalytic receptors. Br J Pharmacol. 2023 10; 180 Suppl 2:S241-S288.

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Dunbar KJ, Karakasheva TA, Tang Q, Efe G, Lin EW, Harris M, Sahu V, Sachdeva UM, Hu J, Klein-Szanto AJ, Henick B, Diehl JA, Nakagawa H, Rustgi AK. Tumor-Derived CCL5 Recruits Cancer-Associated Fibroblasts and Promotes Tumor Cell Proliferation in Esophageal Squamous Cell Carcinoma. Mol Cancer Res. 2023 07 05; 21(7):741-752.

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Tompkins E, Mimic B, Cuevas-Mora K, Schorsch H, Shah SD, Deshpande DA, Benovic JL, Penn RB, Pera T. PD 102807 Induces M3 mAChR-Dependent GRK-/Arrestin-Biased Signaling in Airway Smooth Muscle Cells. Am J Respir Cell Mol Biol. 2022 11; 67(5):550-561.

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