"Lipoprotein Lipase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. The enzyme hydrolyzes triacylglycerols in chylomicrons, very-low-density lipoproteins, low-density lipoproteins, and diacylglycerols. It occurs on capillary endothelial surfaces, especially in mammary, muscle, and adipose tissue. Genetic deficiency of the enzyme causes familial hyperlipoproteinemia Type I. (Dorland, 27th ed) EC 3.1.1.34.
| Descriptor ID |
D008071
|
| MeSH Number(s) |
D08.811.277.352.100.430
|
| Concept/Terms |
Lipoprotein Lipase- Lipoprotein Lipase
- Lipase, Lipoprotein
- Diglyceride Lipase
- Lipase, Diglyceride
- Heparin-Clearing Factor
- Factor, Heparin-Clearing
- Heparin Clearing Factor
- Post-Heparin Lipase
- Lipase, Post-Heparin
- Post Heparin Lipase
- Postheparin Lipase
- Lipase, Postheparin
- Postheparin Lipoprotein Lipase
- Lipase, Postheparin Lipoprotein
- Lipoprotein Lipase, Postheparin
- Diacylglycerol Lipase
- Lipase, Diacylglycerol
- Lipemia-Clearing Factor
- Factor, Lipemia-Clearing
- Lipemia Clearing Factor
|
Below are MeSH descriptors whose meaning is more general than "Lipoprotein Lipase".
Below are MeSH descriptors whose meaning is more specific than "Lipoprotein Lipase".
This graph shows the total number of publications written about "Lipoprotein Lipase" by people in this website by year, and whether "Lipoprotein Lipase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 2 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lipoprotein Lipase" by people in Profiles.
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Chiu J, Valente KN, Levy NE, Min L, Lenhoff AM, Lee KH. Knockout of a difficult-to-remove CHO host cell protein, lipoprotein lipase, for improved polysorbate stability in monoclonal antibody formulations. Biotechnol Bioeng. 2017 05; 114(5):1006-1015.
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Soto AG, McIntyre A, Agrawal S, Bialo SR, Hegele RA, Boney CM. Severe Hypertriglyceridemia due to a novel p.Q240H mutation in the Lipoprotein Lipase gene. Lipids Health Dis. 2015 Sep 04; 14:102.
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Epand RM, Shulga YV, Timmons HC, Perri AL, Belani JD, Perinpanathan K, Johnson-McIntire LB, Bajjalieh S, Dicu AO, Elias C, Rychnovsky SD, Topham MK. Substrate chirality and specificity of diacylglycerol kinases and the multisubstrate lipid kinase. Biochemistry. 2007 Dec 11; 46(49):14225-31.
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Risbud MV, Guttapalli A, Tsai TT, Lee JY, Danielson KG, Vaccaro AR, Albert TJ, Gazit Z, Gazit D, Shapiro IM. Evidence for skeletal progenitor cells in the degenerate human intervertebral disc. Spine (Phila Pa 1976). 2007 Nov 01; 32(23):2537-44.
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Fu M, Rao M, Bouras T, Wang C, Wu K, Zhang X, Li Z, Yao TP, Pestell RG. Cyclin D1 inhibits peroxisome proliferator-activated receptor gamma-mediated adipogenesis through histone deacetylase recruitment. J Biol Chem. 2005 Apr 29; 280(17):16934-41.
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Fuki IV, Kuhn KM, Lomazov IR, Rothman VL, Tuszynski GP, Iozzo RV, Swenson TL, Fisher EA, Williams KJ. The syndecan family of proteoglycans. Novel receptors mediating internalization of atherogenic lipoproteins in vitro. J Clin Invest. 1997 Sep 15; 100(6):1611-22.
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Berkow SE, Spear ML, Stahl GE, Gutman A, Polin RA, Pereira GR, Olivecrona T, Hamosh P, Hamosh M. Total parenteral nutrition with intralipid in premature infants receiving TPN with heparin: effect on plasma lipolytic enzymes, lipids, and glucose. J Pediatr Gastroenterol Nutr. 1987 Jul-Aug; 6(4):581-8.
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Brown JE, Kitchell BB, Bjornsson TD, Shand DG. The artifactual nature of heparin-induced drug protein-binding alterations. Clin Pharmacol Ther. 1981 Nov; 30(5):636-43.