Lymphocyte Depletion

"Lymphocyte Depletion" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Immunosuppression by reduction of circulating lymphocytes or by T-cell depletion of bone marrow. The former may be accomplished in vivo by thoracic duct drainage or administration of antilymphocyte serum. The latter is performed ex vivo on bone marrow before its transplantation.

Descriptor ID	D008212
MeSH Number(s)	E02.095.465.425.450.521 E05.478.610.570
Concept/Terms	Lymphocyte Depletion Lymphocyte Depletion Depletion, Lymphocyte

Below are MeSH descriptors whose meaning is more general than "Lymphocyte Depletion".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Therapeutics [E02]
Biological Therapy [E02.095]
Immunomodulation [E02.095.465]
Immunotherapy [E02.095.465.425]
Immunosuppression [E02.095.465.425.450]
Lymphocyte Depletion [E02.095.465.425.450.521]
Investigative Techniques [E05]
Immunologic Techniques [E05.478]
Immunosuppression [E05.478.610]
Lymphocyte Depletion [E05.478.610.570]

Below are MeSH descriptors whose meaning is related to "Lymphocyte Depletion".

Below are MeSH descriptors whose meaning is more specific than "Lymphocyte Depletion".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Lymphocyte Depletion" by people in this website by year, and whether "Lymphocyte Depletion" was a major or minor topic of these publications.

Bar chart showing 17 publications over 12 distinct years, with a maximum of 3 publications in 1997 and 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	1	2
1997	1	2	3
1998	1	0	1
2000	0	1	1
2004	0	1	1
2005	0	1	1
2012	1	0	1
2013	1	2	3
2015	1	0	1
2017	0	1	1
2019	0	1	1
2021	0	1	1

Below are the most recent publications written about "Lymphocyte Depletion" by people in Profiles.

Manukian G, Kivolowitz C, DeAngelis T, Shastri AA, Savage JE, Camphausen K, Rodeck U, Zarif JC, Simone NL. Caloric Restriction Impairs Regulatory T cells Within the Tumor Microenvironment After Radiation and Primes Effector T cells. Int J Radiat Oncol Biol Phys. 2021 08 01; 110(5):1341-1349.

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Royster GD, Harris JC, Nelson A, Castro Y, Weitzel RP, Tisdale J, Heitmann RJ, DeCherney AH, Wolff EF. Rapamycin Corrects T Regulatory Cell Depletion and Improves Embryo Implantation and Live Birth Rates in a Murine Model. Reprod Sci. 2019 12; 26(12):1545-1556.

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Arce Vargas F, Furness AJS, Solomon I, Joshi K, Mekkaoui L, Lesko MH, Miranda Rota E, Dahan R, Georgiou A, Sledzinska A, Ben Aissa A, Franz D, Werner Sunderland M, Wong YNS, Henry JY, O'Brien T, Nicol D, Challacombe B, Beers SA, Turajlic S, Gore M, Larkin J, Swanton C, Chester KA, Pule M, Ravetch JV, Marafioti T, Peggs KS, Quezada SA. Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors. Immunity. 2017 04 18; 46(4):577-586.

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Wang TT, Ravetch JV. Immune complexes: not just an innocent bystander in chronic viral infection. Immunity. 2015 Feb 17; 42(2):213-215.

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Alpdogan O, Grosso D, Flomenberg N. Recent advances in haploidentical stem cell transplantation. Discov Med. 2013 Oct; 16(88):159-65.

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Simpson TR, Li F, Montalvo-Ortiz W, Sepulveda MA, Bergerhoff K, Arce F, Roddie C, Henry JY, Yagita H, Wolchok JD, Peggs KS, Ravetch JV, Allison JP, Quezada SA. Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti-CTLA-4 therapy against melanoma. J Exp Med. 2013 Aug 26; 210(9):1695-710.

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Quatromoni JG, Suzuki E, Okusanya O, Judy BF, Bhojnagarwala P, Venegas O, Eruslanov E, Predina JD, Albelda SM, Singhal S. The timing of TGF-? inhibition affects the generation of antigen-specific CD8+ T cells. BMC Immunol. 2013 Jul 17; 14:30.

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Grosso D, Flomenberg N. A two-step approach to allogeneic haploidentical hematopoietic stem cell transplantation. Semin Oncol. 2012 Dec; 39(6):694-706.

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Kakhniashvili I, Filicko J, Kraft WK, Flomenberg N. Heterogeneous clearance of antithymocyte globulin after CD34+-selected allogeneic hematopoietic progenitor cell transplantation. Biol Blood Marrow Transplant. 2005 Aug; 11(8):609-18.

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Uchida J, Hamaguchi Y, Oliver JA, Ravetch JV, Poe JC, Haas KM, Tedder TF. The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptor-dependent mechanisms during anti-CD20 antibody immunotherapy. J Exp Med. 2004 Jun 21; 199(12):1659-69.

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