"alpha-Mannosidosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An inborn error of metabolism marked by a defect in the lysosomal isoform of ALPHA-MANNOSIDASE activity that results in lysosomal accumulation of mannose-rich intermediate metabolites. Virtually all patients have psychomotor retardation, facial coarsening, and some degree of dysostosis multiplex. It is thought to be an autosomal recessive disorder.
| Descriptor ID |
D008363
|
| MeSH Number(s) |
C16.320.565.202.607.500 C16.320.565.595.577.500 C18.452.648.202.607.500 C18.452.648.595.577.500
|
| Concept/Terms |
alpha-Mannosidosis- alpha-Mannosidosis
- alpha Mannosidosis
- alpha-Mannosidoses
- Alpha-Mannosidase B Deficiency
- alpha-Mannosidase Deficiency
- Deficiencies, alpha-Mannosidase
- Deficiency, alpha-Mannosidase
- alpha Mannosidase Deficiency
- alpha-Mannosidase Deficiencies
- Lysosomal Alpha B Mannosidosis
- Lysosomal alpha-D-Mannosidase Deficiency
- Deficiencies, Lysosomal alpha-D-Mannosidase
- Deficiency, Lysosomal alpha-D-Mannosidase
- Lysosomal alpha D Mannosidase Deficiency
- Lysosomal alpha-D-Mannosidase Deficiencies
- alpha-D-Mannosidase Deficiencies, Lysosomal
- alpha-D-Mannosidase Deficiency, Lysosomal
- Mannosidosis, alpha B Lysosomal
- Mannosidosis, alpha B, Lysosomal
- Alpha-D-Mannosidosis
- alpha Mannosidase B Deficiency
- Alpha-Mannosidosis, Type I
|
Below are MeSH descriptors whose meaning is more general than "alpha-Mannosidosis".
Below are MeSH descriptors whose meaning is more specific than "alpha-Mannosidosis".
This graph shows the total number of publications written about "alpha-Mannosidosis" by people in this website by year, and whether "alpha-Mannosidosis" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
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Below are the most recent publications written about "alpha-Mannosidosis" by people in Profiles.
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Grewal SS, Shapiro EG, Krivit W, Charnas L, Lockman LA, Delaney KA, Davies SM, Wenger DA, Rimell FL, Abel S, Grovas AC, Orchard PJ, Wagner JE, Peters C. Effective treatment of alpha-mannosidosis by allogeneic hematopoietic stem cell transplantation. J Pediatr. 2004 May; 144(5):569-73.