"Methysergide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An ergot derivative that is a congener of LYSERGIC ACID DIETHYLAMIDE. It antagonizes the effects of serotonin in blood vessels and gastrointestinal smooth muscle, but has few of the properties of other ergot alkaloids. Methysergide is used prophylactically in migraine and other vascular headaches and to antagonize serotonin in the carcinoid syndrome.
| Descriptor ID |
D008784
|
| MeSH Number(s) |
D03.132.327.287.689 D03.633.400.439.689
|
| Concept/Terms |
Methysergide- Methysergide
- Dimethylergometrin
- Methylmethylergonovine
Sansert- Sansert
- Deseril
- Désernil-Sandoz
- Désernil Sandoz
- Desril
|
Below are MeSH descriptors whose meaning is more general than "Methysergide".
Below are MeSH descriptors whose meaning is more specific than "Methysergide".
This graph shows the total number of publications written about "Methysergide" by people in this website by year, and whether "Methysergide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
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Below are the most recent publications written about "Methysergide" by people in Profiles.
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Silberstein SD. Methysergide. Cephalalgia. 1998 Sep; 18(7):421-35.
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Higgins WJ, Price DA, Greenberg MJ. FMRFamide increases the adenylate cyclase activity and cylic AMP level of molluscan heart. Eur J Pharmacol. 1978 Apr 15; 48(4):425-30.
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Higgins WJ, Greenberg MJ. Intracellular actions of 5-hydroxytryptamine on the bivalve myocardium. II. Cyclic nucleotide-dependent protein kinases and microsomal calcium uptake. J Exp Zool. 1974 Dec; 190(3):305-16.
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Levitan IB, Madsen CJ, Barondes SH. Cyclic AMP and amine effects on phosphorylation of specific protein in abdominal ganglion of Aplysia californica; localization and kinetic analysis. J Neurobiol. 1974; 5(6):511-25.
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Agarwal RA, Ligon PJ, Greenberg MJ. The distribution of cardioactive agents among molluscan species and tissues. Comp Gen Pharmacol. 1972 Sep; 3(11):249-60.
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GREENBERG MJ, JEGLA TC. THE ACTION OF 5-HYDROXYTRYPTAMINE AND ACETYLCHOLINE ON THE RECTUM OF THE VENUS CLAM, MERCENARIA MERCENARIA. Comp Biochem Physiol. 1963 Aug; 9:275-90.