"Mexiletine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Antiarrhythmic agent pharmacologically similar to LIDOCAINE. It may have some anticonvulsant properties.
| Descriptor ID |
D008801
|
| MeSH Number(s) |
D02.092.831.500 D02.455.426.559.389.657.654.675
|
| Concept/Terms |
KO-1173- KO-1173
- KO 1173
- KO1173
- KOE-1173
- KOE 1173
- KOE1173
|
Below are MeSH descriptors whose meaning is more general than "Mexiletine".
Below are MeSH descriptors whose meaning is more specific than "Mexiletine".
This graph shows the total number of publications written about "Mexiletine" by people in this website by year, and whether "Mexiletine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 2 | 0 | 2 |
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mexiletine" by people in Profiles.
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Qi D, Yang Z, Robinson VM, Li J, Gao C, Guo D, Kowey PR, Yan GX. Heterogeneous distribution of INa-L determines interregional differences in rate adaptation of repolarization. Heart Rhythm. 2015 Jun; 12(6):1295-303.
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Marmura MJ. Intravenous lidocaine and mexiletine in the management of trigeminal autonomic cephalalgias. Curr Pain Headache Rep. 2010 Apr; 14(2):145-50.
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Marmura MJ, Passero FC, Young WB. Mexiletine for refractory chronic daily headache: a report of nine cases. Headache. 2008 Nov-Dec; 48(10):1506-10.
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Shimizu W, Antzelevitch C, Suyama K, Kurita T, Taguchi A, Aihara N, Takaki H, Sunagawa K, Kamakura S. Effect of sodium channel blockers on ST segment, QRS duration, and corrected QT interval in patients with Brugada syndrome. J Cardiovasc Electrophysiol. 2000 Dec; 11(12):1320-9.
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Shimizu W, Antzelevitch C. Cellular basis for the ECG features of the LQT1 form of the long-QT syndrome: effects of beta-adrenergic agonists and antagonists and sodium channel blockers on transmural dispersion of repolarization and torsade de pointes. Circulation. 1998 Nov 24; 98(21):2314-22.
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Sicouri S, Antzelevitch D, Heilmann C, Antzelevitch C. Effects of sodium channel block with mexiletine to reverse action potential prolongation in in vitro models of the long term QT syndrome. J Cardiovasc Electrophysiol. 1997 Nov; 8(11):1280-90.
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Shimizu W, Antzelevitch C. Sodium channel block with mexiletine is effective in reducing dispersion of repolarization and preventing torsade des pointes in LQT2 and LQT3 models of the long-QT syndrome. Circulation. 1997 Sep 16; 96(6):2038-47.
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Podrid PJ, Kowey PR, Frishman WH, Arnold RJ, Kaniecki DJ, Beck JR, Beshansky JR. Comparative cost-effectiveness analysis of quinidine, procainamide and mexiletine. Am J Cardiol. 1991 Dec 15; 68(17):1662-7.
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Marinchak RA, Friehling TD, Kline RA, Stohler J, Kowey PR. Effect of antiarrhythmic drugs on defibrillation threshold: case report of an adverse effect of mexiletine and review of the literature. Pacing Clin Electrophysiol. 1988 Jan; 11(1):7-12.
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Nestico PF, Morganroth J. Antiarrhythmic agents for chronic ventricular arrhythmias. Compr Ther. 1987 Apr; 13(4):26-35.