Neonatal Abstinence Syndrome

"Neonatal Abstinence Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Fetal and neonatal addiction and withdrawal as a result of the mother's dependence on drugs during pregnancy. Withdrawal or abstinence symptoms develop shortly after birth. Symptoms exhibited are loud, high-pitched crying, sweating, yawning and gastrointestinal disturbances.

Descriptor ID	D009357
MeSH Number(s)	C16.614.610 C25.775.650 F03.900.650
Concept/Terms	Neonatal Abstinence Syndrome Neonatal Abstinence Syndrome Substance Withdrawal, Neonatal Neonatal Withdrawal Syndrome Neonatal Withdrawal Syndromes Syndrome, Neonatal Withdrawal Syndromes, Neonatal Withdrawal Withdrawal Syndrome, Neonatal Withdrawal Syndromes, Neonatal Abstinence Syndrome, Neonatal Abstinence Syndromes, Neonatal Neonatal Abstinence Syndromes Syndrome, Neonatal Abstinence Syndromes, Neonatal Abstinence Neonatal Substance Withdrawal Neonatal Substance Withdrawals Substance Withdrawals, Neonatal Withdrawal, Neonatal Substance Passive Addiction, Neonatal Passive Addiction, Neonatal Addiction, Neonatal Passive Addictions, Neonatal Passive Neonatal Passive Addiction Neonatal Passive Addictions Passive Addictions, Neonatal

Below are MeSH descriptors whose meaning is more general than "Neonatal Abstinence Syndrome".

Diseases [C]
Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
Infant, Newborn, Diseases [C16.614]
Neonatal Abstinence Syndrome [C16.614.610]
Chemically-Induced Disorders [C25]
Substance-Related Disorders [C25.775]
Neonatal Abstinence Syndrome [C25.775.650]
Psychiatry and Psychology [F]
Mental Disorders [F03]
Substance-Related Disorders [F03.900]
Neonatal Abstinence Syndrome [F03.900.650]

Below are MeSH descriptors whose meaning is related to "Neonatal Abstinence Syndrome".

Below are MeSH descriptors whose meaning is more specific than "Neonatal Abstinence Syndrome".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Neonatal Abstinence Syndrome" by people in this website by year, and whether "Neonatal Abstinence Syndrome" was a major or minor topic of these publications.

Bar chart showing 88 publications over 23 distinct years, with a maximum of 9 publications in 2012 and 2019 and 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
2003	1	0	1
2004	1	0	1
2005	1	0	1
2007	2	0	2
2008	3	1	4
2009	1	0	1
2010	6	0	6
2011	1	1	2
2012	7	2	9
2013	2	1	3
2014	1	0	1
2015	3	0	3
2016	5	0	5
2017	5	0	5
2018	6	0	6
2019	9	0	9
2020	6	1	7
2021	2	0	2
2022	4	0	4
2023	3	0	3
2024	8	1	9
2025	3	0	3

Below are the most recent publications written about "Neonatal Abstinence Syndrome" by people in Profiles.

Lam K, Peltz G, Kraft WK. The role of 5-HT modulation in opioid withdrawal and neonatal opioid withdrawal syndrome: mechanisms and potential serotonergic targets. Expert Opin Investig Drugs. 2025 Jan-Feb; 34(1-2):49-59.

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Lam K, Mondick JT, Peltz G, Wu M, Kraft WK. Bayesian Population Pharmacokinetic Modeling of Ondansetron for Neonatal Opioid Withdrawal Syndrome. Clin Transl Sci. 2025 02; 18(2):e70147.

View in: PubMed
Durrance CP, Pac J, Berger LM, Reilly A, Ehrenthal D. Prenatal opioid exposure, neonatal abstinence syndrome diagnosis, and child welfare involvement. Child Abuse Negl. 2025 03; 161:107246.

View in: PubMed
Merhar SL, Hu Z, Devlin LA, Ounpraseuth ST, Simon AE, Smith PB, Walsh MC, Lee JY, Das A, Higgins RD, Crawford MM, Rice W, Paul DA, Maxwell JR, Telang SD, Fung CM, Wright T, Reynolds AM, Hahn D, Ross J, McAllister JM, Crowley M, Shaikh SK, Christ L, Brown J, Riccio J, Wong Ramsey K, Braswell EF, Tucker L, McAlmon K, Dummula K, Weiner J, White JR, Howell MP, Newman S, Snowden JN, Young LW. Infant Feeding and Weight Trajectories in the Eat, Sleep, Console Trial: A Secondary Analysis of a Randomized Clinical Trial. JAMA Pediatr. 2024 Oct 01; 178(10):976-984.

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Wang Y, Ehrenthal DB, Zhang L. Distinct Trajectories of Prescription Opioid Exposure in Pregnancy and Risk of Adverse Birth Outcomes. J Addict Med. 2025 Jan-Feb 01; 19(1):53-61.

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Dhodapkar MM, Jonnalagadda A, Socci AR, Franklin C. Association Between Clubfoot and Neonatal Abstinence Syndrome in the United States, 2018-2022. J Pediatr Orthop. 2025 Jan 01; 45(1):e55-e58.

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Anderson VA, Anbalagan S, Favara MT, Stark D, Carola D, Solarin KO, Adeniyi-Jones S, Aghai ZH. Sex-Related Differences in the Severity of Neonatal Opioid Withdrawal Syndrome: A Single-Center, Retrospective Cohort Study. Am J Perinatol. 2025 02; 42(3):363-368.

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Anbalagan S, Anderson V, Favara MT, Stark D, Carola D, Solarin K, Adeniyi-Jones S, Kraft WK, Aghai ZH. Buprenorphine vs. morphine: impact on neonatal opioid withdrawal syndrome (NOWS) outcomes in a single center retrospective study. J Perinatol. 2025 Apr; 45(4):473-479.

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Devlin LA, Hu Z, Merhar SL, Ounpraseuth ST, Simon AE, Lee JY, Das A, Crawford MM, Greenberg RG, Smith PB, Higgins RD, Walsh MC, Rice W, Paul DA, Maxwell JR, Fung CM, Wright T, Ross J, McAllister JM, Crowley M, Shaikh SK, Christ L, Brown J, Riccio J, Wong Ramsey K, Braswell EF, Tucker L, McAlmon K, Dummula K, Weiner J, White JR, Newman S, Snowden JN, Young LW. Influence of Eat, Sleep, and Console on Infants Pharmacologically Treated for Opioid Withdrawal: A Post Hoc Subgroup Analysis of the ESC-NOW Randomized Clinical Trial. JAMA Pediatr. 2024 06 01; 178(6):525-532.

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Berger LM, Durrance C, Ehrenthal D, Kim H, Kuo HH, Pac J. Prenatal opioid exposure by likelihood of exposure and risk to prenatal development: Medicaid-covered births in Wisconsin, 2010-2019. Sci Adv. 2024 05 10; 10(19):eadg9674.

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