Neural Tube Defects

"Neural Tube Defects" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy generally occurring between days 18-29 of gestation. Ectodermal and mesodermal malformations (mainly involving the skull and vertebrae) may occur as a result of defects of neural tube closure. (From Joynt, Clinical Neurology, 1992, Ch55, pp31-41)

Descriptor ID	D009436
MeSH Number(s)	C10.500.680 C16.131.666.680
Concept/Terms	Neural Tube Defects Neural Tube Defects Defect, Neural Tube Defects, Neural Tube Neural Tube Defect Developmental Neural Tube Defects Neural Tube Developmental Defects Developmental Defects, Neural Tube Craniorachischisis Craniorachischisis Craniorachischises Diastematomyelia Diastematomyelia Diastematomyelias Tethered Cord Syndrome Tethered Cord Syndrome Tethered Cord Syndromes Occult Spinal Dysraphism Sequence Tethered Spinal Cord Syndrome Occult Spinal Dysraphism Dysraphism, Occult Spinal Dysraphisms, Occult Spinal Occult Spinal Dysraphisms Spinal Dysraphism, Occult Spinal Dysraphisms, Occult Iniencephaly Iniencephaly Iniencephalies Neurenteric Cyst Neurenteric Cyst Cyst, Neurenteric Cysts, Neurenteric Neurenteric Cysts Neuroenteric Cyst Cyst, Neuroenteric Cysts, Neuroenteric Neuroenteric Cysts Spinal Cord Myelodysplasia Spinal Cord Myelodysplasia Myelodysplasia, Spinal Cord Myelodysplasias, Spinal Cord Spinal Cord Myelodysplasias Acrania Acrania Acranias Exencephaly Exencephaly Exencephalies

Below are MeSH descriptors whose meaning is more general than "Neural Tube Defects".

Diseases [C]
Nervous System Diseases [C10]
Nervous System Malformations [C10.500]
Neural Tube Defects [C10.500.680]
Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
Congenital Abnormalities [C16.131]
Nervous System Malformations [C16.131.666]
Neural Tube Defects [C16.131.666.680]

Below are MeSH descriptors whose meaning is related to "Neural Tube Defects".

Below are MeSH descriptors whose meaning is more specific than "Neural Tube Defects".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Neural Tube Defects" by people in this website by year, and whether "Neural Tube Defects" was a major or minor topic of these publications.

Bar chart showing 14 publications over 12 distinct years, with a maximum of 2 publications in 2006 and 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	1	0	1
2002	1	0	1
2006	2	0	2
2007	1	0	1
2009	1	1	2
2010	1	0	1
2012	1	0	1
2013	1	0	1
2016	0	1	1
2019	1	0	1
2021	1	0	1
2024	1	0	1

Below are the most recent publications written about "Neural Tube Defects" by people in Profiles.

Das R, Duggal M, Rosenthal J, Kankaria A, Senee HK, Jabbar S, Kaur M, Kumar V, Bhardwaj S, Singh N, Dhanjal GS, Kumar A, Rose CE, Bhatia R, Gupta R, Dalpath S, Crider KS, Zhang M, Pfeiffer CM, Gupta R, Mehta R, Raina N, Yeung LF. Folate and Vitamin B12 Status in Women of Reproductive Age in Rural Haryana, India: Estimating Population-Based Prevalence for Neural Tube Defects. Birth Defects Res. 2024 08; 116(8):e2390.

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Yacob A, Carr CJ, Foote J, Scullen T, Werner C, Mathkour M, Bui CJ, Dumont AS. The Global Burden of Neural Tube Defects and Disparities in Neurosurgical Care. World Neurosurg. 2021 05; 149:e803-e820.

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Passias PG, Poorman GW, Jalai CM, Diebo BG, Vira S, Horn SR, Baker JF, Shenoy K, Hasan S, Buza J, Bronson W, Paul JC, Kaye I, Foster NA, Cassilly RT, Oren JH, Moskovich R, Line B, Oh C, Bess S, LaFage V, Errico TJ. Incidence of Congenital Spinal Abnormalities Among Pediatric Patients and Their Association With Scoliosis and Systemic Anomalies. J Pediatr Orthop. 2019 Sep; 39(8):e608-e613.

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Zak J, Vives V, Szumska D, Vernet A, Schneider JE, Miller P, Slee EA, Joss S, Lacassie Y, Chen E, Escobar LF, Tucker M, Aylsworth AS, Dubbs HA, Collins AT, Andrieux J, Dieux-Coeslier A, Haberlandt E, Kotzot D, Scott DA, Parker MJ, Zakaria Z, Choy YS, Wieczorek D, Innes AM, Jun KR, Zinner S, Prin F, Lygate CA, Pretorius P, Rosenfeld JA, Mohun TJ, Lu X. ASPP2 deficiency causes features of 1q41q42 microdeletion syndrome. Cell Death Differ. 2016 12; 23(12):1973-1984.

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Ranguis SC, Chaganti JR, Winder MJ. A bilateral infratentorial neurenteric cyst. J Clin Neurosci. 2013 May; 20(5):735-8.

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Haas RE, Kecskemethy HH, Lopiccolo MA, Hossain J, Dy RT, Bachrach SJ. Lower extremity bone mineral density in children with congenital spinal dysfunction. Dev Med Child Neurol. 2012 Dec; 54(12):1133-7.

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Samdani AF, Fine AL, Sagoo SS, Shah SC, Cahill PJ, Clements DH, Betz RR. A patient with myelomeningocele: is untethering necessary prior to scoliosis correction? Neurosurg Focus. 2010 Jul; 29(1):E8.

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McGirt MJ, Mehta V, Garces-Ambrossi G, Gottfried O, Solakoglu C, Gokaslan ZL, Samdani A, Jallo GI. Pediatric tethered cord syndrome: response of scoliosis to untethering procedures. Clinical article. J Neurosurg Pediatr. 2009 Sep; 4(3):270-4.

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Pahys JM, Samdani AF, Betz RR. Intraspinal anomalies in infantile idiopathic scoliosis: prevalence and role of magnetic resonance imaging. Spine (Phila Pa 1976). 2009 May 20; 34(12):E434-8.

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Brent RL, Oakley GP. Further efforts to reduce the incidence of neural tube defects. Pediatrics. 2007 Jan; 119(1):225-6.

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