"Pentoxifylline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A METHYLXANTHINE derivative that inhibits phosphodiesterase and affects blood rheology. It improves blood flow by increasing erythrocyte and leukocyte flexibility. It also inhibits platelet aggregation. Pentoxifylline modulates immunologic activity by stimulating cytokine production.
| Descriptor ID |
D010431
|
| MeSH Number(s) |
D03.633.100.759.758.824.651.700
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Pentoxifylline".
Below are MeSH descriptors whose meaning is more specific than "Pentoxifylline".
This graph shows the total number of publications written about "Pentoxifylline" by people in this website by year, and whether "Pentoxifylline" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pentoxifylline" by people in Profiles.
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Fritz MA, Arianpour K, Liu SW, Lamarre ED, Genther DJ, Ciolek PJ, Byrne PJ, Prendes BL. Managing Mandibular Osteoradionecrosis. Otolaryngol Head Neck Surg. 2025 Feb; 172(2):406-418.
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Halegoua-De Marzio DL, Fenkel JM. Treatment of severe alcoholic hepatitis with corticosteroids and pentoxifylline. JAMA. 2013 Sep 11; 310(10):1029-30.
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Gude RP, Binda MM, Presas HL, Klein-Szanto AJ, Bonfil RD. Studies on the mechanisms responsible for inhibition of experimental metastasis of B16-F10 murine melanoma by pentoxifylline. J Biomed Sci. 1999 Mar-Apr; 6(2):133-41.
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Law WR, Nadkarni VM, Fletcher MA, Nevola JJ, Eckstein JM, Quance J, McKenna TM, Lee CH, Williams TJ. Pentoxifylline treatment of sepsis in conscious Yucatan minipigs. Circ Shock. 1992 Aug; 37(4):291-300.
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Fletcher MA, McKenna TM, Owens EH, Nadkarni VM. Effects of in vivo pentoxifylline treatment on survival and ex vivo vascular contractility in a rat lipopolysaccharide shock model. Circ Shock. 1992 Jan; 36(1):74-80.
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Rocci ML, Luke DR, Saccar CL. Pharmacokinetics of pentoxifylline during concomitant theophylline administration to rats. Pharm Res. 1987 Oct; 4(5):433-5.