"Phagosomes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Membrane-bound cytoplasmic vesicles formed by invagination of phagocytized material. They fuse with lysosomes to form phagolysosomes in which the hydrolytic enzymes of the lysosome digest the phagocytized material.
Descriptor ID |
D010588
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MeSH Number(s) |
A11.284.430.214.190.875.190.700
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Phagosomes".
Below are MeSH descriptors whose meaning is more specific than "Phagosomes".
This graph shows the total number of publications written about "Phagosomes" by people in this website by year, and whether "Phagosomes" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 0 | 1 | 1 |
2007 | 0 | 1 | 1 |
2008 | 1 | 0 | 1 |
2012 | 1 | 0 | 1 |
2013 | 0 | 2 | 2 |
2014 | 1 | 0 | 1 |
2015 | 1 | 0 | 1 |
2019 | 1 | 0 | 1 |
2020 | 2 | 0 | 2 |
2022 | 0 | 1 | 1 |
2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Phagosomes" by people in Profiles.
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Scharrig E, Mantegazza AR. Dissecting Phagosomal Pattern Recognition Receptor-Dependent Signaling and Antigen MHC-II Presentation from Phagosomes in Murine?Dendritic Cells. Methods Mol Biol. 2023; 2692:275-287.
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L?pez-Haber C, Netting DJ, Hutchins Z, Ma X, Hamilton KE, Mantegazza AR. The phagosomal solute transporter SLC15A4 promotes inflammasome activity via mTORC1 signaling and autophagy restraint in dendritic cells. EMBO J. 2022 10 17; 41(20):e111161.
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L?pez-Haber C, Levin-Konigsberg R, Zhu Y, Bi-Karchin J, Balla T, Grinstein S, Marks MS, Mantegazza AR. Phosphatidylinositol-4-kinase IIa licenses phagosomes for TLR4 signaling and MHC-II presentation in dendritic cells. Proc Natl Acad Sci U S A. 2020 11 10; 117(45):28251-28262.
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Levin-Konigsberg R, Mantegazza AR. A guide to measuring phagosomal dynamics. FEBS J. 2021 03; 288(5):1412-1433.
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Piplani H, Marek-Iannucci S, Sin J, Hou J, Takahashi T, Sharma A, de Freitas Germano J, Waldron RT, Saadaeijahromi H, Song Y, Gulla A, Wu B, Lugea A, Andres AM, Gaisano HY, Gottlieb RA, Pandol SJ. Simvastatin induces autophagic flux to restore cerulein-impaired phagosome-lysosome fusion in acute pancreatitis. Biochim Biophys Acta Mol Basis Dis. 2019 11 01; 1865(11):165530.
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Mantegazza AR, Marks MS. Visualizing toll-like receptor-dependent phagosomal dynamics in murine dendritic cells using live cell microscopy. Methods Mol Biol. 2015; 1270:191-203.
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Mantegazza AR, Zajac AL, Twelvetrees A, Holzbaur EL, Amigorena S, Marks MS. TLR-dependent phagosome tubulation in dendritic cells promotes phagosome cross-talk to optimize MHC-II antigen presentation. Proc Natl Acad Sci U S A. 2014 Oct 28; 111(43):15508-13.
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Schrock JM, Spino CM, Longen CG, Stabler SM, Marino JC, Pasternak GW, Kim FJ. Sequential cytoprotective responses to Sigma1 ligand-induced endoplasmic reticulum stress. Mol Pharmacol. 2013 Nov; 84(5):751-62.
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Fischer N, Mak TN, Shinohara DB, Sfanos KS, Meyer TF, Brüggemann H. Deciphering the intracellular fate of Propionibacterium acnes in macrophages. Biomed Res Int. 2013; 2013:603046.
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Mantegazza AR, Guttentag SH, El-Benna J, Sasai M, Iwasaki A, Shen H, Laufer TM, Marks MS. Adaptor protein-3 in dendritic cells facilitates phagosomal toll-like receptor signaling and antigen presentation to CD4(+) T cells. Immunity. 2012 May 25; 36(5):782-94.