"Picibanil" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A lyophilized preparation of a low-virulence strain (SU) of Streptococcus pyogenes (S. hemolyticus), inactivated by heating with penicillin G. It has been proposed as a noncytotoxic antineoplastic agent because of its immune system-stimulating activity.
| Descriptor ID |
D010844
|
| MeSH Number(s) |
D20.215.659
|
| Concept/Terms |
OK-432- OK-432
- OK 432
- OK432
- Streptococcal Preparation OK-432
- Streptococcal Preparation OK 432
- Streptococcal Preparation OK432
- Streptococcal OK-432
- Streptococcal OK 432
- Streptococcal OK432
|
Below are MeSH descriptors whose meaning is more general than "Picibanil".
Below are MeSH descriptors whose meaning is more specific than "Picibanil".
This graph shows the total number of publications written about "Picibanil" by people in this website by year, and whether "Picibanil" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 2 | 0 | 2 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Picibanil" by people in Profiles.
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Iwai T, Oebisu N, Hoshi M, Orita K, Yamamoto A, Hamamoto S, Kageyama K, Nakamura H. Promising abscopal effect of combination therapy with thermal tumour ablation and intratumoural OK-432 injection in the rat osteosarcoma model. Sci Rep. 2020 06 15; 10(1):9679.
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Yamamoto A, Hamamoto S, Matsuoka T, Kageyama K, Jogo A, Sohgawa E, Okuma T, Hamuro M, Toyoshima M, Kawabe J, Nagahara H, Miki Y. Spontaneous Regression of Untreated Tumors with Immuno-Radiofrequency Ablation, RF Ablation in Combination with Local Injection of OK-432, in a Patient with Lung Metastases of Colon Cancer. J Vasc Interv Radiol. 2017 03; 28(3):477-479.
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Kong D, Liu Y, Li Z, Cui Q, Wang K, Wu K, Wu G. OK-432 (Sapylin) Reduces Seroma Formation After Axillary Lymphadenectomy in Breast Cancer. J Invest Surg. 2017 Feb; 30(1):1-5.
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Kageyama K, Yamamoto A, Okuma T, Hamamoto S, Takeshita T, Sakai Y, Nishida N, Matsuoka T, Miki Y. Radiofrequency ablation of liver tumors in combination with local OK-432 injection prolongs survival and suppresses distant tumor growth in the rabbit model with intra- and extrahepatic VX2 tumors. Cardiovasc Intervent Radiol. 2013 Oct; 36(5):1383-92.
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Hamamoto S, Okuma T, Yamamoto A, Kageyama K, Takeshita T, Sakai Y, Nishida N, Matsuoka T, Miki Y. Radiofrequency ablation and immunostimulant OK-432: combination therapy enhances systemic antitumor immunity for treatment of VX2 lung tumors in rabbits. Radiology. 2013 May; 267(2):405-13.