"Polyploidy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The chromosomal constitution of a cell containing multiples of the normal number of CHROMOSOMES; includes triploidy (symbol: 3N), tetraploidy (symbol: 4N), etc.
| Descriptor ID |
D011123
|
| MeSH Number(s) |
C23.550.210.702 G05.365.590.175.677 G05.700.740
|
| Concept/Terms |
Polyploidy- Polyploidy
- Polyploidies
- Polyploid
- Polyploids
Polyploid Cell- Polyploid Cell
- Cell, Polyploid
- Cells, Polyploid
- Polyploid Cells
|
Below are MeSH descriptors whose meaning is more general than "Polyploidy".
Below are MeSH descriptors whose meaning is more specific than "Polyploidy".
This graph shows the total number of publications written about "Polyploidy" by people in this website by year, and whether "Polyploidy" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 2 | 0 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 3 | 3 |
| 2014 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Polyploidy" by people in Profiles.
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Pienta KJ, Hammarlund EU, Austin RH, Axelrod R, Brown JS, Amend SR. Cancer cells employ an evolutionarily conserved polyploidization program to resist therapy. Semin Cancer Biol. 2022 06; 81:145-159.
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Gimovsky AC, Pham A, Moreno SC, Nicholas S, Roman A, Weiner S. Genetic abnormalities seen on CVS in early pregnancy failure. J Matern Fetal Neonatal Med. 2020 Jul; 33(13):2142-2147.
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Luff SA, Papoutsakis ET. Megakaryocytic Maturation in Response to Shear Flow Is Mediated by the Activator Protein 1 (AP-1) Transcription Factor via Mitogen-activated Protein Kinase (MAPK) Mechanotransduction. J Biol Chem. 2016 Apr 08; 291(15):7831-43.
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Kosoff RE, Aslan JE, Kostyak JC, Dulaimi E, Chow HY, Prudnikova TY, Radu M, Kunapuli SP, McCarty OJ, Chernoff J. Pak2 restrains endomitosis during megakaryopoiesis and alters cytoskeleton organization. Blood. 2015 May 07; 125(19):2995-3005.
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Paller CJ, Wissing MD, Mendonca J, Sharma A, Kim E, Kim HS, Kortenhorst MS, Gerber S, Rosen M, Shaikh F, Zahurak ML, Rudek MA, Hammers H, Rudin CM, Carducci MA, Kachhap SK. Combining the pan-aurora kinase inhibitor AMG 900 with histone deacetylase inhibitors enhances antitumor activity in prostate cancer. Cancer Med. 2014 Oct; 3(5):1322-35.
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Jiang J, Woulfe DS, Papoutsakis ET. Shear enhances thrombopoiesis and formation of microparticles that induce megakaryocytic differentiation of stem cells. Blood. 2014 Sep 25; 124(13):2094-103.
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Lushnikova T, Bouska A, Odvody J, Dupont WD, Eischen CM. Aging mice have increased chromosome instability that is exacerbated by elevated Mdm2 expression. Oncogene. 2011 Nov 17; 30(46):4622-31.
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Lindsey S, Papoutsakis ET. The aryl hydrocarbon receptor (AHR) transcription factor regulates megakaryocytic polyploidization. Br J Haematol. 2011 Feb; 152(4):469-84.
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Hayashi N, Nakamura S, Yagata H, Shimoda Y, Ota H, Hortobagyi GN, Cristofanilli M, Ueno NT. Chromosome 17 polysomy in circulating tumor cells in patients with metastatic breast cancer: a case series. Int J Clin Oncol. 2011 Oct; 16(5):596-600.
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Panuganti S, Papoutsakis ET, Miller WM. Bone marrow niche-inspired, multiphase expansion of megakaryocytic progenitors with high polyploidization potential. Cytotherapy. 2010 Oct; 12(6):767-82.