Polysorbates

"Polysorbates" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Sorbitan mono-9-octadecanoate poly(oxy-1,2-ethanediyl) derivatives; complex mixtures of polyoxyethylene ethers used as emulsifiers or dispersing agents in pharmaceuticals.

Descriptor ID	D011136
MeSH Number(s)	D02.033.455.250.700.690 D05.750.741.700 D25.720.741.700 J01.637.051.720.741.700
Concept/Terms	Polysorbates Polysorbates PSML Polyoxyethylene Sorbitan Monolaurate Monolaurate, Polyoxyethylene Sorbitan Sorbitan Monolaurate, Polyoxyethylene Tween 60 Tween 60 Tween 81 Tween 81 Tween 85 Tween 85 Sorbitan Derivatives Sorbitan Derivatives Derivatives, Sorbitan Polysorbate 20 Polysorbate 20 Polysorbate 80 Polysorbate 80 Tween 80 Tween 80 Tween 20 Tween 20 Tweens Tweens

Below are MeSH descriptors whose meaning is more general than "Polysorbates".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Alcohols [D02.033]
Glycols [D02.033.455]
Ethylene Glycols [D02.033.455.250]
Polyethylene Glycols [D02.033.455.250.700]
Polysorbates [D02.033.455.250.700.690]
Macromolecular Substances [D05]
Polymers [D05.750]
Polyethylene Glycols [D05.750.741]
Polysorbates [D05.750.741.700]
Biomedical and Dental Materials [D25]
Polymers [D25.720]
Polyethylene Glycols [D25.720.741]
Polysorbates [D25.720.741.700]
Technology, Industry, Agriculture [J]
Technology, Industry, and Agriculture [J01]
Manufactured Materials [J01.637]
Biomedical and Dental Materials [J01.637.051]
Polymers [J01.637.051.720]
Polyethylene Glycols [J01.637.051.720.741]
Polysorbates [J01.637.051.720.741.700]

Below are MeSH descriptors whose meaning is related to "Polysorbates".

Below are MeSH descriptors whose meaning is more specific than "Polysorbates".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Polysorbates" by people in this website by year, and whether "Polysorbates" was a major or minor topic of these publications.

Bar chart showing 11 publications over 8 distinct years, with a maximum of 2 publications in 2008 and 2009 and 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
2006	1	0	1
2008	1	1	2
2009	1	1	2
2010	1	0	1
2016	2	0	2
2020	0	1	1
2023	0	1	1

Below are the most recent publications written about "Polysorbates" by people in Profiles.

Sattler S, Gollomp S, Curry A. A Narrative Literature Review of the Established Safety of Human Serum Albumin Use as a Stabilizer in Aesthetic Botulinum Toxin Formulations Compared to Alternatives. Toxins (Basel). 2023 10 18; 15(10).

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Lederer K, Casta?o D, G?mez Atria D, Oguin TH, Wang S, Manzoni TB, Muramatsu H, Hogan MJ, Amanat F, Cherubin P, Lundgreen KA, Tam YK, Fan SHY, Eisenlohr LC, Maillard I, Weissman D, Bates P, Krammer F, Sempowski GD, Pardi N, Locci M. SARS-CoV-2 mRNA Vaccines Foster Potent Antigen-Specific Germinal Center Responses Associated with Neutralizing Antibody Generation. Immunity. 2020 12 15; 53(6):1281-1295.e5.

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Chiu J, Valente KN, Levy NE, Min L, Lenhoff AM, Lee KH. Knockout of a difficult-to-remove CHO host cell protein, lipoprotein lipase, for improved polysorbate stability in monoclonal antibody formulations. Biotechnol Bioeng. 2017 05; 114(5):1006-1015.

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Yuan X, Ji W, Chen S, Bao Y, Tan S, Lu S, Wu K, Chu Q. A novel paclitaxel-loaded poly(d,l-lactide-co-glycolide)-Tween 80 copolymer nanoparticle overcoming multidrug resistance for lung cancer treatment. Int J Nanomedicine. 2016; 11:2119-31.

View in: PubMed
Solis C, Forsberg F, Wheatley MA. Preserving enhancement in freeze-dried contrast agent ST68: Examination of excipients. Int J Pharm. 2010 Aug 30; 396(1-2):30-8.

View in: PubMed
Forsberg F, Liu JB, Patel M, Liu L, Lin L, Solis C, Fox TB, Wheatley MA. Preclinical acute toxicology study of surfactant-stabilized ultrasound contrast agents in adult rats. Int J Toxicol. 2010 Jan-Feb; 29(1):32-9.

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Cushing DJ, Kowey PR, Cooper WD, Massey BW, Gralinski MR, Lipicky RJ. PM101: a cyclodextrin-based intravenous formulation of amiodarone devoid of adverse hemodynamic effects. Eur J Pharmacol. 2009 Apr 01; 607(1-3):167-72.

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Arhin FF, Tomfohrde K, Draghi DC, Aranza M, Parr TR, Sahm DF, Moeck G. Newly defined in vitro quality control ranges for oritavancin broth microdilution testing and impact of variation in testing parameters. Diagn Microbiol Infect Dis. 2008 Sep; 62(1):92-5.

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Arhin FF, Sarmiento I, Belley A, McKay GA, Draghi DC, Grover P, Sahm DF, Parr TR, Moeck G. Effect of polysorbate 80 on oritavancin binding to plastic surfaces: implications for susceptibility testing. Antimicrob Agents Chemother. 2008 May; 52(5):1597-603.

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Wheatley MA, Forsberg F, Dube N, Patel M, Oeffinger BE. Surfactant-stabilized contrast agent on the nanoscale for diagnostic ultrasound imaging. Ultrasound Med Biol. 2006 Jan; 32(1):83-93.

View in: PubMed

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