"Epoprostenol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from PROSTAGLANDIN ENDOPEROXIDES in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension (HYPERTENSION, PULMONARY).
| Descriptor ID |
D011464
|
| MeSH Number(s) |
D10.251.355.255.550.550.500 D23.469.050.175.725.550.500
|
| Concept/Terms |
Epoprostenol- Epoprostenol
- PGI2
- Prostaglandin I2
- Prostacyclin
- Prostaglandin I(2)
- Epoprostanol
- PGX
Epoprostenol Sodium- Epoprostenol Sodium
- Epoprostenol Sodium Salt, (5Z,9alpha,11alpha,13E,15S)-Isomer
|
Below are MeSH descriptors whose meaning is more general than "Epoprostenol".
Below are MeSH descriptors whose meaning is more specific than "Epoprostenol".
This graph shows the total number of publications written about "Epoprostenol" by people in this website by year, and whether "Epoprostenol" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Epoprostenol" by people in Profiles.
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Bustin A, Ramsey EZ, Hanna BD, Kaushal G. Compatibility of treprostinil sodium and dopamine hydrochloride during simulated Y-site administration. Am J Health Syst Pharm. 2020 Apr 01; 77(8):649-657.
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Raychaudhuri B, Malur A, Bonfield TL, Abraham S, Schilz RJ, Farver CF, Kavuru MS, Arroliga AC, Thomassen MJ. The prostacyclin analogue treprostinil blocks NFkappaB nuclear translocation in human alveolar macrophages. J Biol Chem. 2002 Sep 06; 277(36):33344-8.
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Tan HP, Markowitz JS, Montgomery RA, Merritt WT, Klein AS, Thuluvath PJ, Poordad FF, Maley WR, Winters B, Akinci SB, Gaine SP. Liver transplantation in patients with severe portopulmonary hypertension treated with preoperative chronic intravenous epoprostenol. Liver Transpl. 2001 Aug; 7(8):745-9.
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Greene RM, Lloyd MR, Pisano MM. Cyclic AMP-dependent protein kinase in human embryonic palate mesenchymal cells. In Vitro Cell Dev Biol. 1992 Nov-Dec; 28A(11-12):755-62.
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Landolfi R, Castellana MA, De Cristofaro R, De Candia E, Bizzi B. Effect of picotamide on prostacyclin production by human endothelial cells. Thromb Haemost. 1988 Dec 22; 60(3):529.
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Landolfi R, De Cristofaro R, Ciabattoni G, De Carolis S, Durazzi S, Mancini S, Bizzi B. Placental-derived PGI2 inhibits cord blood platelet function. Haematologica. 1988 May-Jun; 73(3):207-10.
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Prosdocimi M, Tessari F, Finesso M, Gorio A, Dejana E, Languino LR, Del Maschio A, de Gaetano G. Prostacyclin and thromboxane levels during cardiac ischemia in dogs. Adv Prostaglandin Thromboxane Leukot Res. 1985; 13:93-6.
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Landolfi R, Steiner M. Ethanol raises prostacyclin in vivo and in vitro. Blood. 1984 Sep; 64(3):679-82.
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Kowey PR, Verrier RL, Lown B, Handin RI. Influence of intracoronary platelet aggregation on ventricular electrical properties during partial coronary artery stenosis. Am J Cardiol. 1983 Feb; 51(3):596-602.
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Ingerman-Wojenski C, Silver MJ, Smith JB, Macarak E. Bovine endothelial cells in culture produce thromboxane as well as prostacyclin. J Clin Invest. 1981 May; 67(5):1292-6.