"Protoporphyrins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Porphyrins with four methyl, two vinyl, and two propionic acid side chains attached to the pyrrole rings. Protoporphyrin IX occurs in hemoglobin, myoglobin, and most of the cytochromes.
| Descriptor ID |
D011524
|
| MeSH Number(s) |
D03.383.129.578.840.500.725 D03.633.400.909.500.725 D04.345.783.500.725 D23.767.727.725
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Protoporphyrins".
Below are MeSH descriptors whose meaning is more specific than "Protoporphyrins".
This graph shows the total number of publications written about "Protoporphyrins" by people in this website by year, and whether "Protoporphyrins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Protoporphyrins" by people in Profiles.
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Chen-Roetling J, Cai Y, Lu X, Regan RF. Hemin uptake and release by neurons and glia. Free Radic Res. 2014 Feb; 48(2):200-5.
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Metz R, Duhadaway JB, Rust S, Munn DH, Muller AJ, Mautino M, Prendergast GC. Zinc protoporphyrin IX stimulates tumor immunity by disrupting the immunosuppressive enzyme indoleamine 2,3-dioxygenase. Mol Cancer Ther. 2010 Jun; 9(6):1864-71.
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Zabalgoitia M, Colston JT, Reddy SV, Holt JW, Regan RF, Stec DE, Rimoldi JM, Valente AJ, Chandrasekar B. Carbon monoxide donors or heme oxygenase-1 (HO-1) overexpression blocks interleukin-18-mediated NF-kappaB-PTEN-dependent human cardiac endothelial cell death. Free Radic Biol Med. 2008 Feb 01; 44(3):284-98.
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Rattan S, Regan RF, Patel CA, De Godoy MA. Nitric oxide not carbon monoxide mediates nonadrenergic noncholinergic relaxation in the murine internal anal sphincter. Gastroenterology. 2005 Dec; 129(6):1954-66.
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Rogers B, Yakopson V, Teng ZP, Guo Y, Regan RF. Heme oxygenase-2 knockout neurons are less vulnerable to hemoglobin toxicity. Free Radic Biol Med. 2003 Oct 15; 35(8):872-81.
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Argyris EG, Vanderkooi JM, Venkateswaran PS, Kay BK, Paterson Y. The connection domain is implicated in metalloporphyrin binding and inhibition of HIV reverse transcriptase. J Biol Chem. 1999 Jan 15; 274(3):1549-56.
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Campbell DL, Fisher ME, Johnson JG, Rossi FM, Campling BG, Pottier RH, Kennedy JC. Flow cytometric technique for quantitating cytotoxic response to photodynamic therapy. Photochem Photobiol. 1996 Jan; 63(1):111-6.
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Pastorino JG, Simbula G, Gilfor E, Hoek JB, Farber JL. Protoporphyrin IX, an endogenous ligand of the peripheral benzodiazepine receptor, potentiates induction of the mitochondrial permeability transition and the killing of cultured hepatocytes by rotenone. J Biol Chem. 1994 Dec 09; 269(49):31041-6.
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Smith SM, Schroedl NA. Heme-containing compounds replace chick embryo extract and enhance differentiation in avian muscle cell culture. In Vitro Cell Dev Biol. 1992 Jun; 28A(6):387-90.
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Selbst SM, Henretig FM, Pearce J. Lead encephalopathy. A case report and review of management. Clin Pediatr (Phila). 1985 May; 24(5):280-2, 285.