Purpura, Thrombotic Thrombocytopenic
"Purpura, Thrombotic Thrombocytopenic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An acquired, congenital, or familial disorder caused by PLATELET AGGREGATION with THROMBOSIS in terminal arterioles and capillaries. Clinical features include THROMBOCYTOPENIA; HEMOLYTIC ANEMIA; AZOTEMIA; FEVER; and thrombotic microangiopathy. The classical form also includes neurological symptoms and end-organ damage, such as RENAL FAILURE.
| Descriptor ID |
D011697
|
| MeSH Number(s) |
C15.378.100.802.687.680 C15.378.140.855.925.750.680 C15.378.925.850 C23.550.414.950.687.680 C23.888.885.687.687.680
|
| Concept/Terms |
Purpura, Thrombotic Thrombocytopenic- Purpura, Thrombotic Thrombocytopenic
- Thrombocytopenic Purpura, Thrombotic
- Moschkowitz Disease
- Disease, Moschkowitz
- Thrombotic Thrombocytopenic Purpura
- Moschcowitz Disease
- Disease, Moschcowitz
- Purpura, Thrombotic Thrombopenic
- Thrombopenic Purpura, Thrombotic
- Thrombotic Thrombopenic Purpura
Congenital Thrombotic Thrombocytopenic Purpura- Congenital Thrombotic Thrombocytopenic Purpura
- Schulman-Upshaw Syndrome
- Schulman Upshaw Syndrome
- Syndrome, Schulman-Upshaw
- Upshaw-Schulman Syndrome
- Syndrome, Upshaw-Schulman
- Upshaw Schulman Syndrome
- Thrombotic Thrombocytopenic Purpura, Congenital
- Upshaw Factor, Deficiency of
- Microangiopathic Hemolytic Anemia, Congenital
- Thrombotic Microangiopathy, Familial
- Familial Thrombotic Microangiopathy
- Microangiopathy, Familial Thrombotic
|
Below are MeSH descriptors whose meaning is more general than "Purpura, Thrombotic Thrombocytopenic".
- Diseases [C]
- Hemic and Lymphatic Diseases [C15]
- Hematologic Diseases [C15.378]
- Blood Coagulation Disorders [C15.378.100]
- Purpura [C15.378.100.802]
- Purpura, Thrombocytopenic [C15.378.100.802.687]
- Purpura, Thrombotic Thrombocytopenic [C15.378.100.802.687.680]
- Blood Platelet Disorders [C15.378.140]
- Thrombocytopenia [C15.378.140.855]
- Thrombotic Microangiopathies [C15.378.140.855.925]
- Purpura, Thrombocytopenic [C15.378.140.855.925.750]
- Purpura, Thrombotic Thrombocytopenic [C15.378.140.855.925.750.680]
- Thrombophilia [C15.378.925]
- Purpura, Thrombotic Thrombocytopenic [C15.378.925.850]
- Pathological Conditions, Signs and Symptoms [C23]
- Pathologic Processes [C23.550]
- Hemorrhage [C23.550.414]
- Purpura [C23.550.414.950]
- Purpura, Thrombocytopenic [C23.550.414.950.687]
- Purpura, Thrombotic Thrombocytopenic [C23.550.414.950.687.680]
- Signs and Symptoms [C23.888]
- Skin Manifestations [C23.888.885]
- Purpura [C23.888.885.687]
- Purpura, Thrombocytopenic [C23.888.885.687.687]
- Purpura, Thrombotic Thrombocytopenic [C23.888.885.687.687.680]
Below are MeSH descriptors whose meaning is more specific than "Purpura, Thrombotic Thrombocytopenic".
This graph shows the total number of publications written about "Purpura, Thrombotic Thrombocytopenic" by people in this website by year, and whether "Purpura, Thrombotic Thrombocytopenic" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 2 | 0 | 2 |
| 2005 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 2 | 0 | 2 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Purpura, Thrombotic Thrombocytopenic" by people in Profiles.
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Jarrett SA, Wattoo A, Chiang B, Varadi G, Al Madani M. An 80-Year-Old Man with Ischemic Heart Disease Who Developed Thrombotic Thrombocytopenic Purpura Following Treatment with Ticagrelor. Am J Case Rep. 2022 Aug 24; 23:e936977.
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Kurian CJ, French Z, Kukulich P, Lankiewicz M, Ghimire S, Maarouf OH, Rizk S, Rhoades R. Case series: coronavirus disease 2019 infection as a precipitant of atypical hemolytic uremic syndrome: two case reports. J Med Case Rep. 2021 Dec 13; 15(1):587.
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Reddy MS, Hofmann S, Shen YM, Nagalla S, Rambally S, Usmani A, Sarode R. Comparison of low fixed dose versus standard-dose rituximab to treat thrombotic thrombocytopenic purpura in the acute phase and preemptively during remission. Transfus Apher Sci. 2020 Dec; 59(6):102885.
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Adili R, Holinstat M. Formation and Resolution of Pial Microvascular Thrombosis in a Mouse Model of Thrombotic Thrombocytopenic Purpura. Arterioscler Thromb Vasc Biol. 2019 09; 39(9):1817-1830.
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Bhoopalan SV, Hankins J, George J, Ryder A, Onder AM, Puri L. Use of caplacizumab in a child with refractory thrombotic thrombocytopenic purpura. Pediatr Blood Cancer. 2019 07; 66(7):e27737.
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Peedin AR, Park YA, Mazepa MA, Rollins-Raval MA, Brecher ME, Raval JS. Predictive Value of Schistocytes in Recurrence of Acquired Thrombotic Thrombocytopenic Purpura With Severe ADAMTS13 Deficiency at Discontinuation of Daily Therapeutic Plasma Exchange. Ther Apher Dial. 2018 Dec; 22(6):662-665.
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Hurwitz A, Massone R, Lopez BL. Acquired Bleeding Disorders. Hematol Oncol Clin North Am. 2017 12; 31(6):1123-1145.
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Ramakrishnan Geethakumari P, Rubin A, Varadi G. Thrombotic thrombocytopenic purpura and cardiac papillary fibroelastoma: a 'unique coexistence'. Blood Coagul Fibrinolysis. 2013 Dec; 24(8):881-3.
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Gupta S, Ttan N, Topolsky D, Sesok-Pizzini D, Crilley P, Balasubramanian M, Kahn SB, Brodsky I, Ward K, Styler M. Thrombotic thrombocytopenic purpura induced by cyclosporin a after allogeneic bone marrow transplantation treated by red blood cell exchange transfusion: a case report. Am J Hematol. 2005 Nov; 80(3):246-7.
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Sakarcan A, Stallworth J. Systemic lupus erythematosus and thrombotic thrombocytopenic purpura: a case and review. Pediatr Nephrol. 2001 Aug; 16(8):672-4.