Receptors, Adrenergic, alpha
"Receptors, Adrenergic, alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the two major pharmacological subdivisions of adrenergic receptors that were originally defined by the relative potencies of various adrenergic compounds. The alpha receptors were initially described as excitatory receptors that post-junctionally stimulate SMOOTH MUSCLE contraction. However, further analysis has revealed a more complex picture involving several alpha receptor subtypes and their involvement in feedback regulation.
| Descriptor ID |
D011942
|
| MeSH Number(s) |
D12.776.543.750.670.300.300.300 D12.776.543.750.695.150.300.300 D12.776.543.750.720.330.300.300
|
| Concept/Terms |
Receptors, Adrenergic, alpha- Receptors, Adrenergic, alpha
- Adrenergic alpha-Receptors
- Adrenergic alpha Receptors
- alpha-Receptors, Adrenergic
- alpha-Adrenergic Receptors
- alpha Adrenergic Receptors
- Receptor, Adrenergic, alpha
- Receptors, alpha-Adrenergic
- Receptors, alpha Adrenergic
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Adrenergic, alpha".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.670]
- Receptors, Catecholamine [D12.776.543.750.670.300]
- Receptors, Adrenergic [D12.776.543.750.670.300.300]
- Receptors, Adrenergic, alpha [D12.776.543.750.670.300.300.300]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Catecholamine [D12.776.543.750.695.150]
- Receptors, Adrenergic [D12.776.543.750.695.150.300]
- Receptors, Adrenergic, alpha [D12.776.543.750.695.150.300.300]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Catecholamine [D12.776.543.750.720.330]
- Receptors, Adrenergic [D12.776.543.750.720.330.300]
- Receptors, Adrenergic, alpha [D12.776.543.750.720.330.300.300]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Adrenergic, alpha".
This graph shows the total number of publications written about "Receptors, Adrenergic, alpha" by people in this website by year, and whether "Receptors, Adrenergic, alpha" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 1 | 2 |
| 1998 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Adrenergic, alpha" by people in Profiles.
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Richards JR, Hollander JE, Ramoska EA, Fareed FN, Sand IC, Izquierdo G?mez MM, Lange RA. ?-Blockers, Cocaine, and the Unopposed a-Stimulation Phenomenon. J Cardiovasc Pharmacol Ther. 2017 05; 22(3):239-249.
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O-Uchi J, Rice JJ, Ruwald MH, Parks XX, Ronzier E, Moss AJ, Zareba W, Lopes CM. Impaired IKs channel activation by Ca(2+)-dependent PKC shows correlation with emotion/arousal-triggered events in LQT1. J Mol Cell Cardiol. 2015 Feb; 79:203-11.
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Eckhart AD, Duncan SJ, Penn RB, Benovic JL, Lefkowitz RJ, Koch WJ. Hybrid transgenic mice reveal in vivo specificity of G protein-coupled receptor kinases in the heart. Circ Res. 2000 Jan 7-21; 86(1):43-50.
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Carman CV, Benovic JL. G-protein-coupled receptors: turn-ons and turn-offs. Curr Opin Neurobiol. 1998 Jun; 8(3):335-44.
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Eckhart AD, Zhu Z, Arendshorst WJ, Faber JE. Oxygen modulates alpha 1B-adrenergic receptor gene expression by arterial but not venous vascular smooth muscle. Am J Physiol. 1996 Oct; 271(4 Pt 2):H1599-608.
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Ryan SV, Carrithers SL, Parkinson SJ, Skurk C, Nuss C, Pooler PM, Owen CS, Lefer AM, Waldman SA. Hypotensive mechanisms of amifostine. J Clin Pharmacol. 1996 Apr; 36(4):365-73.
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Anthone GJ, Orandle MS, Wang BH, Yeo CJ. Neuropeptide Y-induced intestinal absorption: mediation by alpha 2-adrenergic receptors. Surgery. 1991 Dec; 110(6):1132-8.
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Yeo CJ, Couse NF, Zinner MJ. Discrimination between alpha 1- and alpha 2-adrenergic receptors in the isolated perfused ileum. Surgery. 1988 Aug; 104(2):130-6.
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Lefkowitz RJ, Kobilka BK, Benovic JL, Bouvier M, Cotecchia S, Hausdorff WP, Dohlman HG, Regan JW, Caron MG. Molecular biology of adrenergic receptors. Cold Spring Harb Symp Quant Biol. 1988; 53 Pt 1:507-14.
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Benovic JL, Regan JW, Matsui H, Mayor F, Cotecchia S, Leeb-Lundberg LM, Caron MG, Lefkowitz RJ. Agonist-dependent phosphorylation of the alpha 2-adrenergic receptor by the beta-adrenergic receptor kinase. J Biol Chem. 1987 Dec 25; 262(36):17251-3.