Receptors, Adrenergic, alpha
"Receptors, Adrenergic, alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the two major pharmacological subdivisions of adrenergic receptors that were originally defined by the relative potencies of various adrenergic compounds. The alpha receptors were initially described as excitatory receptors that post-junctionally stimulate SMOOTH MUSCLE contraction. However, further analysis has revealed a more complex picture involving several alpha receptor subtypes and their involvement in feedback regulation.
Descriptor ID |
D011942
|
MeSH Number(s) |
D12.776.543.750.670.300.300.300 D12.776.543.750.695.150.300.300 D12.776.543.750.720.330.300.300
|
Concept/Terms |
Receptors, Adrenergic, alpha- Receptors, Adrenergic, alpha
- Adrenergic alpha-Receptors
- Adrenergic alpha Receptors
- alpha-Receptors, Adrenergic
- alpha-Adrenergic Receptors
- alpha Adrenergic Receptors
- Receptor, Adrenergic, alpha
- Receptors, alpha-Adrenergic
- Receptors, alpha Adrenergic
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Adrenergic, alpha".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.670]
- Receptors, Catecholamine [D12.776.543.750.670.300]
- Receptors, Adrenergic [D12.776.543.750.670.300.300]
- Receptors, Adrenergic, alpha [D12.776.543.750.670.300.300.300]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Catecholamine [D12.776.543.750.695.150]
- Receptors, Adrenergic [D12.776.543.750.695.150.300]
- Receptors, Adrenergic, alpha [D12.776.543.750.695.150.300.300]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Catecholamine [D12.776.543.750.720.330]
- Receptors, Adrenergic [D12.776.543.750.720.330.300]
- Receptors, Adrenergic, alpha [D12.776.543.750.720.330.300.300]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Adrenergic, alpha".
This graph shows the total number of publications written about "Receptors, Adrenergic, alpha" by people in this website by year, and whether "Receptors, Adrenergic, alpha" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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1996 | 1 | 1 | 2 |
1998 | 1 | 0 | 1 |
2000 | 0 | 1 | 1 |
2016 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Receptors, Adrenergic, alpha" by people in Profiles.
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Richards JR, Hollander JE, Ramoska EA, Fareed FN, Sand IC, Izquierdo G?mez MM, Lange RA. ?-Blockers, Cocaine, and the Unopposed a-Stimulation Phenomenon. J Cardiovasc Pharmacol Ther. 2017 05; 22(3):239-249.
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Eckhart AD, Duncan SJ, Penn RB, Benovic JL, Lefkowitz RJ, Koch WJ. Hybrid transgenic mice reveal in vivo specificity of G protein-coupled receptor kinases in the heart. Circ Res. 2000 Jan 7-21; 86(1):43-50.
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Carman CV, Benovic JL. G-protein-coupled receptors: turn-ons and turn-offs. Curr Opin Neurobiol. 1998 Jun; 8(3):335-44.
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Eckhart AD, Zhu Z, Arendshorst WJ, Faber JE. Oxygen modulates alpha 1B-adrenergic receptor gene expression by arterial but not venous vascular smooth muscle. Am J Physiol. 1996 Oct; 271(4 Pt 2):H1599-608.
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Ryan SV, Carrithers SL, Parkinson SJ, Skurk C, Nuss C, Pooler PM, Owen CS, Lefer AM, Waldman SA. Hypotensive mechanisms of amifostine. J Clin Pharmacol. 1996 Apr; 36(4):365-73.
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O'Rourke B, Reibel DK, Thomas AP. Alpha-adrenergic modification of the Ca2+ transient and contraction in single rat cardiomyocytes. J Mol Cell Cardiol. 1992 Aug; 24(8):809-20.
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Jahnel U, Nawrath H, Shieh RC, Sharma VK, Williford DJ, Sheu SS. Modulation of cytosolic free calcium concentration by alpha 1-adrenoceptors in rat atrial cells. Naunyn Schmiedebergs Arch Pharmacol. 1992 Jul; 346(1):88-93.
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Agrawal DK, Wildrick DM, Boman BM. Characteristics of alpha-adrenoceptors in two human colorectal cancer cell lines. Biochem Biophys Res Commun. 1992 May 29; 185(1):176-84.
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Anthone GJ, Orandle MS, Wang BH, Yeo CJ. Neuropeptide Y-induced intestinal absorption: mediation by alpha 2-adrenergic receptors. Surgery. 1991 Dec; 110(6):1132-8.
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Foster KA, Hock CE, Reibel DK. Altered responsiveness of hypertrophied rat hearts to alpha- and beta-adrenergic stimulation. J Mol Cell Cardiol. 1991 Jan; 23(1):91-101.