Receptors, Transferrin

"Receptors, Transferrin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Membrane glycoproteins found in high concentrations on iron-utilizing cells. They specifically bind iron-bearing transferrin, are endocytosed with its ligand and then returned to the cell surface where transferrin without its iron is released.

Descriptor ID	D011990
MeSH Number(s)	D12.776.157.905.500 D12.776.543.750.800
Concept/Terms	Receptors, Transferrin Receptors, Transferrin Transferrin Receptor Receptor, Transferrin Transferrin Receptors

Below are MeSH descriptors whose meaning is more general than "Receptors, Transferrin".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Transferrin-Binding Proteins [D12.776.157.905]
Receptors, Transferrin [D12.776.157.905.500]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, Transferrin [D12.776.543.750.800]

Below are MeSH descriptors whose meaning is related to "Receptors, Transferrin".

Below are MeSH descriptors whose meaning is more specific than "Receptors, Transferrin".

Receptors, Transferrin
Bacterial Transferrin Receptor Complex

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptors, Transferrin" by people in this website by year, and whether "Receptors, Transferrin" was a major or minor topic of these publications.

Bar chart showing 22 publications over 15 distinct years, with a maximum of 3 publications in 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	1	0	1
1998	0	2	2
1999	1	0	1
2000	1	1	2
2002	1	1	2
2003	1	0	1
2004	1	0	1
2008	2	0	2
2009	1	1	2
2010	1	0	1
2011	1	2	3
2012	0	1	1
2017	1	0	1
2018	0	1	1
2023	0	1	1

Below are the most recent publications written about "Receptors, Transferrin" by people in Profiles.

Parrow NL, Fleming RE. Transferrin receptor 1: keeper of HFE. Blood. 2023 01 26; 141(4):332-333.

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Ginzburg YZ, Fleming RE. Tfr2 suppression benefits ?-thalassemic erythropoiesis. Blood. 2018 11 22; 132(21):2215-2216.

View in: PubMed
Li H, Choesang T, Bao W, Chen H, Feola M, Garcia-Santos D, Li J, Sun S, Follenzi A, Pham P, Liu J, Zhang J, Ponka P, An X, Mohandas N, Fleming RE, Rivella S, Li G, Ginzburg YZ. Decreasing TfR1 expression reverses anemia and hepcidin suppression in ?-thalassemic mice. Blood. 2017 03 16; 129(11):1514-1526.

View in: PubMed
Vujic Spasic M, Sparla R, Mleczko-Sanecka K, Migas MC, Breitkopf-Heinlein K, Dooley S, Vaulont S, Fleming RE, Muckenthaler MU. Smad6 and Smad7 are co-regulated with hepcidin in mouse models of iron overload. Biochim Biophys Acta. 2013 Jan; 1832(1):76-84.

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Chen-Roetling J, Liu W, Regan RF. Iron accumulation and neurotoxicity in cortical cultures treated with holotransferrin. Free Radic Biol Med. 2011 Dec 01; 51(11):1966-74.

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Corradini E, Rozier M, Meynard D, Odhiambo A, Lin HY, Feng Q, Migas MC, Britton RS, Babitt JL, Fleming RE. Iron regulation of hepcidin despite attenuated Smad1,5,8 signaling in mice without transferrin receptor 2 or Hfe. Gastroenterology. 2011 Nov; 141(5):1907-14.

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Swinkels DW, Fleming RE. Novel observations in hereditary hemochromatosis: potential implications for clinical strategies. Haematologica. 2011 Apr; 96(4):485-8.

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Chua AC, Delima RD, Morgan EH, Herbison CE, Tirnitz-Parker JE, Graham RM, Fleming RE, Britton RS, Bacon BR, Olynyk JK, Trinder D. Iron uptake from plasma transferrin by a transferrin receptor 2 mutant mouse model of haemochromatosis. J Hepatol. 2010 Mar; 52(3):425-31.

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H?nninen MM, Haapasalo J, Haapasalo H, Fleming RE, Britton RS, Bacon BR, Parkkila S. Expression of iron-related genes in human brain and brain tumors. BMC Neurosci. 2009 Apr 22; 10:36.

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Fleming RE. Iron sensing as a partnership: HFE and transferrin receptor 2. Cell Metab. 2009 Mar; 9(3):211-2.

View in: PubMed

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