Below are the most recent publications written about "Thymidylate Synthase" by people in Profiles.
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Islam Z, Gurevic I, Strutzenberg TS, Ghosh AK, Iqbal T, Kohen A. Bacterial versus human thymidylate synthase: Kinetics and functionality. PLoS One. 2018; 13(5):e0196506.
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Niedzwiecki D, Hasson RM, Lenz HJ, Ye C, Redston M, Ogino S, Fuchs CS, Compton CC, Mayer RJ, Goldberg RM, Colacchio TA, Saltz LB, Warren RS, Bertagnolli MM. A Study of Thymidylate Synthase Expression as a Biomarker for Resectable Colon Cancer: Alliance (Cancer and Leukemia Group B) 9581 and 89803. Oncologist. 2017 01; 22(1):107-114.
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Ghosh AK, Islam Z, Krueger J, Abeysinghe T, Kohen A. The general base in the thymidylate synthase catalyzed proton abstraction. Phys Chem Chem Phys. 2015 Dec 14; 17(46):30867-75.
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Islam Z, Strutzenberg TS, Gurevic I, Kohen A. Concerted versus stepwise mechanism in thymidylate synthase. J Am Chem Soc. 2014 Jul 16; 136(28):9850-3.
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Roston D, Islam Z, Kohen A. Kinetic isotope effects as a probe of hydrogen transfers to and from common enzymatic cofactors. Arch Biochem Biophys. 2014 Feb 15; 544:96-104.
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Argiris A, Karamouzis MV, Smith R, Kotsakis A, Gibson MK, Lai SY, Kim S, Branstetter BF, Shuai Y, Romkes M, Wang L, Grandis JR, Ferris RL, Johnson JT, Heron DE. Phase I trial of pemetrexed in combination with cetuximab and concurrent radiotherapy in patients with head and neck cancer. Ann Oncol. 2011 Nov; 22(11):2482-2488.
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Argiris A, Karamouzis MV, Gooding WE, Branstetter BF, Zhong S, Raez LE, Savvides P, Romkes M. Phase II trial of pemetrexed and bevacizumab in patients with recurrent or metastatic head and neck cancer. J Clin Oncol. 2011 Mar 20; 29(9):1140-5.
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Rouissi K, Stambouli N, Marrakchi R, Slama MR, Cherif M, Sfaxi M, Chebil M, Elgaaied AB, Ouerhani S. Smoking and polymorphisms in folate metabolizing genes and their effects on the histological stage and grade for bladder tumors. Bull Cancer. 2011 Feb; 98(2):E1-10.
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Rouissi K, Ouerhani S, Oliveira E, Marrakchi R, Cherni L, Ben Othman F, Ben Slama MR, Sfaxi M, Ayed M, Chebil M, Amorim A, Prata MJ, Benammar Elgaaied A. Polymorphisms in one-carbon metabolism pathway genes and risk for bladder cancer in a Tunisian population. Cancer Genet Cytogenet. 2009 Nov; 195(1):43-53.
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Brody JR, Hucl T, Costantino CL, Eshleman JR, Gallmeier E, Zhu H, van der Heijden MS, Winter JM, Wikiewicz AK, Yeo CJ, Kern SE. Limits to thymidylate synthase and TP53 genes as predictive determinants for fluoropyrimidine sensitivity and further evidence for RNA-based toxicity as a major influence. Cancer Res. 2009 Feb 01; 69(3):984-91.