Trypsin Inhibitor, Bowman-Birk Soybean
"Trypsin Inhibitor, Bowman-Birk Soybean" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A low-molecular-weight protein (minimum molecular weight 8000) which has the ability to inhibit trypsin as well as chymotrypsin at independent binding sites. It is characterized by a high cystine content and the absence of glycine.
| Descriptor ID |
D014358
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| MeSH Number(s) |
D12.776.765.741.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Trypsin Inhibitor, Bowman-Birk Soybean".
Below are MeSH descriptors whose meaning is more specific than "Trypsin Inhibitor, Bowman-Birk Soybean".
This graph shows the total number of publications written about "Trypsin Inhibitor, Bowman-Birk Soybean" by people in this website by year, and whether "Trypsin Inhibitor, Bowman-Birk Soybean" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 2 | 0 | 2 |
| 2020 | 0 | 2 | 2 |
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Below are the most recent publications written about "Trypsin Inhibitor, Bowman-Birk Soybean" by people in Profiles.
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Casella G, Rasouli J, Mason K, Boehm A, Kumar G, Hwang D, Thome R, Ishikawa L, Zhang GX, Ciric B, Rostami A. A serine protease inhibitor suppresses autoimmune neuroinflammation by activating the STING/IFN-? axis in macrophages. Cell Mol Immunol. 2020 12; 17(12):1278-1280.
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Safavi F, Thome R, Li Z, Wang L, Rasouli J, Ciric B, Zhang GX, Rostami A. A serine protease inhibitor induces type 1 regulatory T cells through IFN-?/STAT1 signaling. Cell Mol Immunol. 2020 09; 17(9):1004-1006.
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Safavi F, Rostami A. Role of serine proteases in inflammation: Bowman-Birk protease inhibitor (BBI) as a potential therapy for autoimmune diseases. Exp Mol Pathol. 2012 Dec; 93(3):428-33.
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Dai H, Ciric B, Zhang GX, Rostami A. Interleukin-10 plays a crucial role in suppression of experimental autoimmune encephalomyelitis by Bowman-Birk inhibitor. J Neuroimmunol. 2012 Apr; 245(1-2):1-7.
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Dai H, Ciric B, Zhang GX, Rostami A. Bowman-Birk Inhibitor attenuates experimental autoimmune encephalomyelitis by delaying infiltration of inflammatory cells into the CNS. Immunol Res. 2011 Dec; 51(2-3):145-52.
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Touil T, Ciric B, Ventura E, Shindler KS, Gran B, Rostami A. Bowman-Birk inhibitor suppresses autoimmune inflammation and neuronal loss in a mouse model of multiple sclerosis. J Neurol Sci. 2008 Aug 15; 271(1-2):191-202.
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Gran B, Tabibzadeh N, Martin A, Ventura ES, Ware JH, Zhang GX, Parr JL, Kennedy AR, Rostami AM. The protease inhibitor, Bowman-Birk Inhibitor, suppresses experimental autoimmune encephalomyelitis: a potential oral therapy for multiple sclerosis. Mult Scler. 2006 Dec; 12(6):688-97.