"TRPA1 Cation Channel" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A highly conserved, non-selective TRP cation channel that contains 14-17 ANKYRIN REPEATS. It functions in cold sensation and NOCICEPTION of endogenous inflammatory factors and volatile irritants. TRPA1 is also activated by CANNABINOIDS and may play a role in sound perception by hair cells of the inner ear.
| Descriptor ID |
D000074025
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| MeSH Number(s) |
D12.776.157.530.400.901.250 D12.776.543.585.400.901.250
|
| Concept/Terms |
TRPA1 Cation Channel- TRPA1 Cation Channel
- Cation Channel, TRPA1
- Channel, TRPA1 Cation
- TRPA1 Channel
- Channel, TRPA1
- Transient Receptor Potential Cation Channel Subfamily A, Member 1
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Below are MeSH descriptors whose meaning is more general than "TRPA1 Cation Channel".
Below are MeSH descriptors whose meaning is more specific than "TRPA1 Cation Channel".
This graph shows the total number of publications written about "TRPA1 Cation Channel" by people in this website by year, and whether "TRPA1 Cation Channel" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "TRPA1 Cation Channel" by people in Profiles.
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Lamaze A, ?zt?rk-?olak A, Fischer R, Peschel N, Koh K, Jepson JE. Regulation of sleep plasticity by a thermo-sensitive circuit in Drosophila. Sci Rep. 2017 01 13; 7:40304.
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Jha A, Sharma P, Anaparti V, Ryu MH, Halayko AJ. A role for transient receptor potential ankyrin 1 cation channel (TRPA1) in airway hyper-responsiveness? Can J Physiol Pharmacol. 2015 Mar; 93(3):171-6.
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Edelmayer RM, Le LN, Yan J, Wei X, Nassini R, Materazzi S, Preti D, Appendino G, Geppetti P, Dodick DW, Vanderah TW, Porreca F, Dussor G. Activation of TRPA1 on dural afferents: a potential mechanism of headache pain. Pain. 2012 Sep; 153(9):1949-1958.
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del Camino D, Murphy S, Heiry M, Barrett LB, Earley TJ, Cook CA, Petrus MJ, Zhao M, D'Amours M, Deering N, Brenner GJ, Costigan M, Hayward NJ, Chong JA, Fanger CM, Woolf CJ, Patapoutian A, Moran MM. TRPA1 contributes to cold hypersensitivity. J Neurosci. 2010 Nov 10; 30(45):15165-74.