Prostatic Neoplasms, Castration-Resistant

"Prostatic Neoplasms, Castration-Resistant" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Tumors or cancer of the PROSTATE which can grow in the presence of low or residual amount of androgen hormones such as TESTOSTERONE.

Descriptor ID	D064129
MeSH Number(s)	C04.588.945.440.770.500 C12.294.260.750.500 C12.294.565.625.500 C12.758.409.750.500
Concept/Terms	Prostatic Neoplasms, Castration-Resistant Prostatic Neoplasms, Castration-Resistant Castration-Resistant Prostatic Neoplasm Neoplasm, Castration-Resistant Prostatic Neoplasms, Castration-Resistant Prostatic Prostatic Neoplasm, Castration-Resistant Prostatic Neoplasms, Castration Resistant Androgen-Insensitive Prostatic Neoplasms Androgen Insensitive Prostatic Neoplasms Androgen-Resistant Prostatic Neoplasms Androgen Resistant Prostatic Neoplasms Prostatic Neoplasms, Hormone Refractory Hormone Refractory Prostatic Neoplasms Prostatic Neoplasms, Androgen-Independent Androgen-Independent Prostatic Neoplasm Neoplasm, Androgen-Independent Prostatic Neoplasms, Androgen-Independent Prostatic Prostatic Neoplasm, Androgen-Independent Prostatic Neoplasms, Androgen Independent Prostatic Neoplasms, Androgen-Insensitive Androgen-Insensitive Prostatic Neoplasm Neoplasm, Androgen-Insensitive Prostatic Neoplasms, Androgen-Insensitive Prostatic Prostatic Neoplasm, Androgen-Insensitive Prostatic Neoplasms, Androgen Insensitive Prostatic Neoplasms, Androgen-Resistant Androgen-Resistant Prostatic Neoplasm Neoplasm, Androgen-Resistant Prostatic Neoplasms, Androgen-Resistant Prostatic Prostatic Neoplasm, Androgen-Resistant Prostatic Neoplasms, Androgen Resistant Androgen-Independent Prostatic Neoplasms Androgen Independent Prostatic Neoplasms Castration-Resistant Prostatic Neoplasms Castration Resistant Prostatic Neoplasms Prostatic Cancer, Castration-Resistant Prostatic Cancer, Castration-Resistant Cancer, Castration-Resistant Prostatic Cancers, Castration-Resistant Prostatic Castration-Resistant Prostatic Cancers Prostatic Cancer, Castration Resistant Prostatic Cancers, Castration-Resistant Androgen-Insensitive Prostatic Cancer Androgen Insensitive Prostatic Cancer Androgen-Resistant Prostatic Cancer Androgen Resistant Prostatic Cancer Prostatic Cancer, Hormone Refractory Hormone Refractory Prostatic Cancer Prostatic Cancer, Androgen-Independent Androgen-Independent Prostatic Cancers Cancer, Androgen-Independent Prostatic Cancers, Androgen-Independent Prostatic Prostatic Cancer, Androgen Independent Prostatic Cancers, Androgen-Independent Prostatic Cancer, Androgen-Insensitive Androgen-Insensitive Prostatic Cancers Cancer, Androgen-Insensitive Prostatic Cancers, Androgen-Insensitive Prostatic Prostatic Cancer, Androgen Insensitive Prostatic Cancers, Androgen-Insensitive Prostatic Cancer, Androgen-Resistant Androgen-Resistant Prostatic Cancers Cancer, Androgen-Resistant Prostatic Cancers, Androgen-Resistant Prostatic Prostatic Cancer, Androgen Resistant Prostatic Cancers, Androgen-Resistant Androgen-Independent Prostatic Cancer Androgen Independent Prostatic Cancer Castration-Resistant Prostatic Cancer Castration Resistant Prostatic Cancer

Below are MeSH descriptors whose meaning is more general than "Prostatic Neoplasms, Castration-Resistant".

Diseases [C]
Neoplasms [C04]
Neoplasms by Site [C04.588]
Urogenital Neoplasms [C04.588.945]
Genital Neoplasms, Male [C04.588.945.440]
Prostatic Neoplasms [C04.588.945.440.770]
Prostatic Neoplasms, Castration-Resistant [C04.588.945.440.770.500]
Male Urogenital Diseases [C12]
Genital Diseases, Male [C12.294]
Genital Neoplasms, Male [C12.294.260]
Prostatic Neoplasms [C12.294.260.750]
Prostatic Neoplasms, Castration-Resistant [C12.294.260.750.500]
Prostatic Diseases [C12.294.565]
Prostatic Neoplasms [C12.294.565.625]
Prostatic Neoplasms, Castration-Resistant [C12.294.565.625.500]
Urogenital Neoplasms [C12.758]
Genital Neoplasms, Male [C12.758.409]
Prostatic Neoplasms [C12.758.409.750]
Prostatic Neoplasms, Castration-Resistant [C12.758.409.750.500]

Below are MeSH descriptors whose meaning is related to "Prostatic Neoplasms, Castration-Resistant".

Below are MeSH descriptors whose meaning is more specific than "Prostatic Neoplasms, Castration-Resistant".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Prostatic Neoplasms, Castration-Resistant" by people in this website by year, and whether "Prostatic Neoplasms, Castration-Resistant" was a major or minor topic of these publications.

Bar chart showing 234 publications over 13 distinct years, with a maximum of 29 publications in 2023 and 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2013	6	1	7
2014	14	2	16
2015	16	0	16
2016	14	0	14
2017	18	1	19
2018	17	2	19
2019	17	0	17
2020	22	1	23
2021	17	1	18
2022	23	0	23
2023	29	0	29
2024	23	6	29
2025	4	0	4

Below are the most recent publications written about "Prostatic Neoplasms, Castration-Resistant" by people in Profiles.

Beer TM, George DJ, Shore ND, Winters-Stone K, Wefel JS, Verholen F, Srinivasan S, Ortiz J, Morgans AK. Functional assessment in patients with castration-resistant prostate cancer treated with darolutamide: results from the DaroAcT study. Oncologist. 2025 Jul 04; 30(7).

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Castro E, Figliuzzi R, Walsh S, Craigie S, Nazari J, Niyazov A, Samjoo IA. Systematic literature review and meta-analysis of health state utility values in metastatic castration-resistant prostate cancer. Oncologist. 2025 Jul 04; 30(7).

View in: PubMed
Castro E, Ellis J, Craigie S, Haltner A, Nazari J, Niyazov A, Samjoo IA. Comparative efficacy and safety of talazoparib plus enzalutamide and other first-line treatments for metastatic castration-resistant prostate cancer. Oncologist. 2025 Mar 10; 30(3).

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Axeen S, Chen AJ, Lakdawalla DN, Masia N, Niyazov A, Arondekar B, Freedland SJ. Do trial benefits predict real-world gains in metastatic castration resistant prostate cancer. JNCI Cancer Spectr. 2025 Mar 03; 9(2).

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Stein MN, Dumbrava EE, Teply BA, Gergis US, Guiterrez ME, Reshef R, Subudhi SK, Jacquemont CF, Senesac JH, Bayle JH, Scripture CD, Chatwal MS, Bilen MA, Stadler WM, Becerra CR. PSCA-targeted BPX-601 CAR T cells with pharmacological activation by rimiducid in metastatic pancreatic and prostate cancer: a phase 1 dose escalation trial. Nat Commun. 2024 12 30; 15(1):10743.

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DerSarkissian M, Arondekar B, Gupta D, Ivanova J, Niyazov A, Zanardo E, Guo T, Wang J, Duh MS, Freedland SJ. Racial Differences in Survival and Healthcare Resource Utilization Among Medicaid-Insured Adults With Metastatic Prostate Cancer. Clin Genitourin Cancer. 2025 Apr; 23(2):102291.

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Castro E, Wang D, Walsh S, Craigie S, Haltner A, Nazari J, Niyazov A, Samjoo IA. Talazoparib plus enzalutamide versus olaparib plus abiraterone acetate and niraparib plus abiraterone acetate for metastatic castration-resistant prostate cancer: a matching-adjusted indirect comparison. Prostate Cancer Prostatic Dis. 2025 09; 28(3):817-827.

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Bryce AH, Agarwal N, Beltran H, Hussain MH, Sartor O, Shore N, Antonarakis ES, Armstrong AJ, Calais J, Carducci MA, Dorff TB, Efstathiou JA, Gleave M, Gomella LG, Higano C, Hope TA, Iagaru A, Morgans AK, Morris DS, Morris MJ, Petrylak DP, Reiter RE, Rettig MB, Ryan CJ, Sellinger SB, Spratt DE, Srinivas S, Tagawa ST, Taplin ME, Yu EY, Zhang T, McKay RR, Koo PJ, Crawford ED. Implementing evidence-based strategies for men with biochemically recurrent and advanced prostate cancer: Consensus recommendations from the US Prostate Cancer Conference 2024. Cancer. 2025 Jan 01; 131(1):e35612.

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Azad AA, Fizazi K, Matsubara N, Saad F, De Giorgi U, Joung JY, Fong PCC, Jones RJ, Zsch?bitz S, Oldenburg J, Shore ND, Dunshee C, Carles J, Fay AP, Lin X, DeAnnuntis L, Di Santo N, Zielinski MA, Agarwal N. Talazoparib plus enzalutamide in metastatic castration-resistant prostate cancer: Safety analyses from the randomized, placebo-controlled, phase III TALAPRO-2 study. Eur J Cancer. 2024 Dec; 213:115078.

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McManus HD, Dorff T, Morgans AK, Sartor O, Shore N, Armstrong AJ. Navigating therapeutic sequencing in the metastatic castration-resistant prostate cancer patient journey. Prostate Cancer Prostatic Dis. 2025 09; 28(3):672-683.

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