WW Domain-Containing Oxidoreductase
"WW Domain-Containing Oxidoreductase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A short chain oxidoreductase that contains two N-terminal WW DOMAINS and functions as a tumor suppressor and in APOPTOSIS. It is also required for bone development.
| Descriptor ID |
D000074584
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| MeSH Number(s) |
D08.811.682.047.820.900.500 D12.776.624.776.980
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "WW Domain-Containing Oxidoreductase".
Below are MeSH descriptors whose meaning is more specific than "WW Domain-Containing Oxidoreductase".
This graph shows the total number of publications written about "WW Domain-Containing Oxidoreductase" by people in this website by year, and whether "WW Domain-Containing Oxidoreductase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 3 | 3 |
| 2007 | 0 | 2 | 2 |
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Below are the most recent publications written about "WW Domain-Containing Oxidoreductase" by people in Profiles.
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Aqeilan RI, Hagan JP, Aqeilan HA, Pichiorri F, Fong LY, Croce CM. Inactivation of the Wwox gene accelerates forestomach tumor progression in vivo. Cancer Res. 2007 Jun 15; 67(12):5606-10.
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Cantor JP, Iliopoulos D, Rao AS, Druck T, Semba S, Han SY, McCorkell KA, Lakshman TV, Collins JE, Wachsberger P, Friedberg JS, Huebner K. Epigenetic modulation of endogenous tumor suppressor expression in lung cancer xenografts suppresses tumorigenicity. Int J Cancer. 2007 Jan 01; 120(1):24-31.
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Guler G, Uner A, Guler N, Han SY, Iliopoulos D, McCue P, Huebner K. Concordant loss of fragile gene expression early in breast cancer development. Pathol Int. 2005 Aug; 55(8):471-8.
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Nunez MI, Rosen DG, Ludes-Meyers JH, Abba MC, Kil H, Page R, Klein-Szanto AJ, Godwin AK, Liu J, Mills GB, Aldaz CM. WWOX protein expression varies among ovarian carcinoma histotypes and correlates with less favorable outcome. BMC Cancer. 2005 Jun 27; 5:64.
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Iliopoulos D, Guler G, Han SY, Johnston D, Druck T, McCorkell KA, Palazzo J, McCue PA, Baffa R, Huebner K. Fragile genes as biomarkers: epigenetic control of WWOX and FHIT in lung, breast and bladder cancer. Oncogene. 2005 Feb 24; 24(9):1625-33.