PAX6 Transcription Factor
"PAX6 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A paired box transcription factor that has important functions in the development of the eye, nose, central nervous system and pancreas. Mutations in the PAX6 gene are associated with ocular disorders such as ANIRIDIA.
| Descriptor ID |
D000071841
|
| MeSH Number(s) |
D12.776.260.645.813 D12.776.930.700.813
|
| Concept/Terms |
PAX6 Transcription Factor- PAX6 Transcription Factor
- Factor, PAX6 Transcription
- Transcription Factor, PAX6
- Pax-6 Protein
- Pax 6 Protein
- Protein, Pax-6
- Paired Box Gene 6 Protein
- Oculorhombin
- Paired Box Transcription Factor 6
- Transcription Factor PAX6
- Factor PAX6, Transcription
- PAX6, Transcription Factor
- Aniridia Type II Protein
- PAX6 Protein
- Protein, PAX6
- Paired Box Protein Pax-6
- Paired Box Protein Pax 6
|
Below are MeSH descriptors whose meaning is more general than "PAX6 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "PAX6 Transcription Factor".
This graph shows the total number of publications written about "PAX6 Transcription Factor" by people in this website by year, and whether "PAX6 Transcription Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "PAX6 Transcription Factor" by people in Profiles.
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Yeung J, Goldowitz D. Wls expression in the rhombic lip orchestrates the embryonic development of the mouse cerebellum. Neuroscience. 2017 06 23; 354:30-42.
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Yeung J, Ha TJ, Swanson DJ, Goldowitz D. A Novel and Multivalent Role of Pax6 in Cerebellar Development. J Neurosci. 2016 08 31; 36(35):9057-69.
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Zhang P, Ha T, Larouche M, Swanson D, Goldowitz D. Kruppel-Like Factor 4 Regulates Granule Cell Pax6 Expression and Cell Proliferation in Early Cerebellar Development. PLoS One. 2015; 10(7):e0134390.
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Yeung J, Ha TJ, Swanson DJ, Choi K, Tong Y, Goldowitz D. Wls provides a new compartmental view of the rhombic lip in mouse cerebellar development. J Neurosci. 2014 Sep 10; 34(37):12527-37.
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Ha TJ, Swanson DJ, Kirova R, Yeung J, Choi K, Tong Y, Chesler EJ, Goldowitz D. Genome-wide microarray comparison reveals downstream genes of Pax6 in the developing mouse cerebellum. Eur J Neurosci. 2012 Oct; 36(7):2888-98.
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Swanson DJ, Goldowitz D. Experimental Sey mouse chimeras reveal the developmental deficiencies of Pax6-null granule cells in the postnatal cerebellum. Dev Biol. 2011 Mar 01; 351(1):1-12.
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Li S, Goldowitz D, Swanson DJ. The requirement of pax6 for postnatal eye development: evidence from experimental mouse chimeras. Invest Ophthalmol Vis Sci. 2007 Jul; 48(7):3292-300.
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Kang LI, Wang Y, Suckow AT, Czymmek KJ, Cooke VG, Naik UP, Duncan MK. Deletion of JAM-A causes morphological defects in the corneal epithelium. Int J Biochem Cell Biol. 2007; 39(3):576-85.
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Swanson DJ, Tong Y, Goldowitz D. Disruption of cerebellar granule cell development in the Pax6 mutant, Sey mouse. Brain Res Dev Brain Res. 2005 Dec 07; 160(2):176-93.
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Mazet F, Hutt JA, Millard J, Shimeld SM. Pax gene expression in the developing central nervous system of Ciona intestinalis. Gene Expr Patterns. 2003 Dec; 3(6):743-5.