1-Methyl-3-isobutylxanthine
"1-Methyl-3-isobutylxanthine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates CYCLIC NUCLEOTIDE-REGULATED PROTEIN KINASES
| Descriptor ID |
D015056
|
| MeSH Number(s) |
D03.633.100.759.758.824.751.500
|
| Concept/Terms |
1-Methyl-3-isobutylxanthine- 1-Methyl-3-isobutylxanthine
- 1 Methyl 3 isobutylxanthine
- IBMX
- Isobutyltheophylline
- 3-Isobutyl-1-methylxanthine
- 3 Isobutyl 1 methylxanthine
|
Below are MeSH descriptors whose meaning is more general than "1-Methyl-3-isobutylxanthine".
Below are MeSH descriptors whose meaning is more specific than "1-Methyl-3-isobutylxanthine".
This graph shows the total number of publications written about "1-Methyl-3-isobutylxanthine" by people in this website by year, and whether "1-Methyl-3-isobutylxanthine" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
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Below are the most recent publications written about "1-Methyl-3-isobutylxanthine" by people in Profiles.
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Garthwaite G, Batchelor AM, Goodwin DA, Hewson AK, Leeming K, Ahmed Z, Cuzner ML, Garthwaite J. Pathological implications of iNOS expression in central white matter: an ex vivo study of optic nerves from rats with experimental allergic encephalomyelitis. Eur J Neurosci. 2005 Apr; 21(8):2127-35.
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Griffiths C, Garthwaite G, Goodwin DA, Garthwaite J. Dynamics of nitric oxide during simulated ischaemia-reperfusion in rat striatal slices measured using an intrinsic biosensor, soluble guanylyl cyclase. Eur J Neurosci. 2002 Mar; 15(6):962-8.
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Gaballa MA, Eckhart A, Koch WJ, Goldman S. Vascular beta-adrenergic receptor system is dysfunctional after myocardial infarction. Am J Physiol Heart Circ Physiol. 2001 Mar; 280(3):H1129-35.
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Garthwaite G, Goodwin DA, Garthwaite J. Nitric oxide stimulates cGMP formation in rat optic nerve axons, providing a specific marker of axon viability. Eur J Neurosci. 1999 Dec; 11(12):4367-72.
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Greene RM, Lloyd MR, Pisano MM. Cyclic AMP-dependent protein kinase in human embryonic palate mesenchymal cells. In Vitro Cell Dev Biol. 1992 Nov-Dec; 28A(11-12):755-62.
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Schr?der H, Leitman DC, Bennett BM, Waldman SA, Murad F. Glyceryl trinitrate-induced desensitization of guanylate cyclase in cultured rat lung fibroblasts. J Pharmacol Exp Ther. 1988 May; 245(2):413-8.
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Fiscus RR, Robles BT, Waldman SA, Murad F. Atrial natriuretic factors stimulate accumulation and efflux of cyclic GMP in C6-2B rat glioma and PC12 rat pheochromocytoma cell cultures. J Neurochem. 1987 Feb; 48(2):522-8.
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Freerksen DL, Schroedl NA, Johnson GV, Hartzell CR. Increased aerobic glucose oxidation by cAMP in cultured regenerated skeletal myotubes. Am J Physiol. 1986 May; 250(5 Pt 1):C713-9.
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Dettori-Gera C, Ronner P, Scarpa A. Difference in dose-response curves for glucose-induced insulin and somatostatin release in rat pancreas. Biochim Biophys Acta. 1985 May 08; 839(3):281-6.