3,4-Methylenedioxyamphetamine
"3,4-Methylenedioxyamphetamine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An amphetamine derivative that inhibits uptake of catecholamine neurotransmitters. It is a hallucinogen. It is less toxic than its methylated derivative but in sufficient doses may still destroy serotonergic neurons and has been used for that purpose experimentally.
| Descriptor ID |
D015104
|
| MeSH Number(s) |
D02.092.471.683.152.660
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "3,4-Methylenedioxyamphetamine".
Below are MeSH descriptors whose meaning is more specific than "3,4-Methylenedioxyamphetamine".
This graph shows the total number of publications written about "3,4-Methylenedioxyamphetamine" by people in this website by year, and whether "3,4-Methylenedioxyamphetamine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 2 | 2 |
| 2007 | 1 | 0 | 1 |
| 2009 | 2 | 2 | 4 |
| 2013 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "3,4-Methylenedioxyamphetamine" by people in Profiles.
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Baggott MJ, Garrison KJ, Coyle JR, Galloway GP, Barnes AJ, Huestis MA, Mendelson JE. Effects of the Psychedelic Amphetamine MDA (3,4-Methylenedioxyamphetamine) in Healthy Volunteers. J Psychoactive Drugs. 2019 Apr-Jun; 51(2):108-117.
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Krotulski AJ, Mohr ALA, Papsun DM, Logan BK. Dibutylone (bk-DMBDB): Intoxications, Quantitative Confirmations and Metabolism in Authentic Biological Specimens. J Anal Toxicol. 2018 Sep 01; 42(7):437-445.
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Concheiro M, Baumann MH, Scheidweiler KB, Rothman RB, Marrone GF, Huestis MA. Nonlinear pharmacokinetics of (+/-)3,4-methylenedioxymethamphetamine (MDMA) and its pharmacodynamic consequences in the rat. Drug Metab Dispos. 2014 Jan; 42(1):119-25.
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Scheidweiler KB, Ladenheim B, Cadet JL, Huestis MA. Mice lacking multidrug resistance protein 1a show altered dopaminergic responses to methylenedioxymethamphetamine (MDMA) in striatum. Neurotox Res. 2010 Aug; 18(2):200-9.
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Abraham TT, Barnes AJ, Lowe RH, Kolbrich Spargo EA, Milman G, Pirnay SO, Gorelick DA, Goodwin RS, Huestis MA. Urinary MDMA, MDA, HMMA, and HMA excretion following controlled MDMA administration to humans. J Anal Toxicol. 2009 Oct; 33(8):439-46.
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Mueller M, Kolbrich EA, Peters FT, Maurer HH, McCann UD, Huestis MA, Ricaurte GA. Direct comparison of (+/-) 3,4-methylenedioxymethamphetamine ("ecstasy") disposition and metabolism in squirrel monkeys and humans. Ther Drug Monit. 2009 Jun; 31(3):367-73.
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Mueller M, Peters FT, Huestis MA, Ricaurte GA, Maurer HH. Simultaneous liquid chromatographic-electrospray ionization mass spectrometric quantification of 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy) and its metabolites 3,4-dihydroxymethamphetamine, 4-hydroxy-3-methoxymethamphetamine and 3,4-methylenedioxyamphetamine in squirrel monkey and human plasma after acidic conjugate cleavage. Forensic Sci Int. 2009 Jan 30; 184(1-3):64-8.
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Kolbrich EA, Lowe RH, Huestis MA. Two-dimensional gas chromatography/electron-impact mass spectrometry with cryofocusing for simultaneous quantification of MDMA, MDA, HMMA, HMA, and MDEA in human plasma. Clin Chem. 2008 Feb; 54(2):379-87.
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Pirnay SO, Abraham TT, Lowe RH, Huestis MA. Selection and optimization of hydrolysis conditions for the quantification of urinary metabolites of MDMA. J Anal Toxicol. 2006 Oct; 30(8):563-9.
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Pirnay SO, Abraham TT, Huestis MA. Sensitive gas chromatography-mass spectrometry method for simultaneous measurement of MDEA, MDMA, and metabolites HMA, MDA, and HMMA in human urine. Clin Chem. 2006 Sep; 52(9):1728-34.