"4-Butyrolactone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the FURANS with a carbonyl thereby forming a cyclic lactone. It is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate. It is also used as a pharmacological agent and solvent.
| Descriptor ID |
D015107
|
| MeSH Number(s) |
D02.540.150 D03.383.312.150
|
| Concept/Terms |
4-Butyrolactone- 4-Butyrolactone
- 4 Butyrolactone
- Dihydro-2(3H)-furanone
- gamma-Butyrolactone
- gamma Butyrolactone
- Furanone, tetrahydro-2-
- Furanone, tetrahydro 2
- 1,4-Butanolide
- 1,4 Butanolide
- 4-Hydroxybutyric Acid Lactone
- 4 Hydroxybutyric Acid Lactone
- Lactone, 4-Hydroxybutyric Acid
|
Below are MeSH descriptors whose meaning is more general than "4-Butyrolactone".
Below are MeSH descriptors whose meaning is more specific than "4-Butyrolactone".
This graph shows the total number of publications written about "4-Butyrolactone" by people in this website by year, and whether "4-Butyrolactone" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "4-Butyrolactone" by people in Profiles.
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DePalma JW, Horan AJ, Hall WA, Johnston MV. Thermodynamics of oligomer formation: implications for secondary organic aerosol formation and reactivity. Phys Chem Chem Phys. 2013 May 14; 15(18):6935-44.
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Flefel EM, Abdel-Mageid RE, Tantawy WA, Ali MA, Amr Ael-G. Heterocyclic compounds based on 3-(4-bromophenyl) azo-5-phenyl-2(3H)-furanone: anti-avian influenza virus (H5N1) activity. Acta Pharm. 2012 Dec; 62(4):593-606.
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Debler EW, Kaufmann GF, Kirchdoerfer RN, Mee JM, Janda KD, Wilson IA. Crystal structures of a quorum-quenching antibody. J Mol Biol. 2007 May 18; 368(5):1392-402.
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Couper FJ, Logan BK. Addicted to driving under the influence--a GHB/GBL case report. J Anal Toxicol. 2004 Sep; 28(6):512-5.
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Blanchard JL, Epstein DM, Boisclair MD, Rudolph J, Pal K. Dysidiolide and related gamma-hydroxy butenolide compounds as inhibitors of the protein tyrosine phosphatase, CDC25. Bioorg Med Chem Lett. 1999 Sep 06; 9(17):2537-8.