Calcium Channels

"Calcium Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Voltage-dependent cell membrane glycoproteins selectively permeable to calcium ions. They are categorized as L-, T-, N-, P-, Q-, and R-types based on the activation and inactivation kinetics, ion specificity, and sensitivity to drugs and toxins. The L- and T-types are present throughout the cardiovascular and central nervous systems and the N-, P-, Q-, & R-types are located in neuronal tissue.

Descriptor ID	D015220
MeSH Number(s)	D12.776.157.530.400.150 D12.776.543.550.450.150 D12.776.543.585.400.150
Concept/Terms	Calcium Channels Calcium Channels Ion Channel, Calcium Calcium Ion Channel Ion Channels, Calcium Calcium Ion Channels Calcium Channel Blocker Receptor VDCC Receptors, Calcium Channel Blocker Calcium Channel Antagonist Receptors Receptors, Calcium Channel Antagonist Calcium Channel Antagonist Receptor Voltage-Dependent Calcium Channels Calcium Channels, Voltage-Dependent Channels, Voltage-Dependent Calcium Voltage Dependent Calcium Channels Calcium Channel Calcium Channel Blocker Receptors

Below are MeSH descriptors whose meaning is more general than "Calcium Channels".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Membrane Transport Proteins [D12.776.157.530]
Ion Channels [D12.776.157.530.400]
Calcium Channels [D12.776.157.530.400.150]
Membrane Proteins [D12.776.543]
Membrane Glycoproteins [D12.776.543.550]
Ion Channels [D12.776.543.550.450]
Calcium Channels [D12.776.543.550.450.150]
Membrane Transport Proteins [D12.776.543.585]
Ion Channels [D12.776.543.585.400]
Calcium Channels [D12.776.543.585.400.150]

Below are MeSH descriptors whose meaning is related to "Calcium Channels".

Below are MeSH descriptors whose meaning is more specific than "Calcium Channels".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Calcium Channels" by people in this website by year, and whether "Calcium Channels" was a major or minor topic of these publications.

Bar chart showing 97 publications over 28 distinct years, with a maximum of 8 publications in 1997 and 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	1	2
1997	7	1	8
1998	2	1	3
1999	4	2	6
2000	5	0	5
2001	5	0	5
2002	2	0	2
2003	2	2	4
2004	3	0	3
2005	7	1	8
2006	3	0	3
2007	1	1	2
2008	1	1	2
2009	1	0	1
2010	6	1	7
2011	2	4	6
2012	1	1	2
2013	1	1	2
2014	3	0	3
2015	3	1	4
2016	3	0	3
2017	4	1	5
2018	1	0	1
2019	2	0	2
2021	0	3	3
2022	1	0	1
2023	1	1	2
2024	0	2	2

Below are the most recent publications written about "Calcium Channels" by people in Profiles.

Hasan P, Berezhnaya E, Rodr?guez-Prados M, Weaver D, Bekeova C, Cartes-Saavedra B, Birch E, Beyer AM, Santos JH, Seifert EL, Elrod JW, Hajn?czky G. MICU1 and MICU2 control mitochondrial calcium signaling in the mammalian heart. Proc Natl Acad Sci U S A. 2024 08 27; 121(35):e2402491121.

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Rodr?guez NA, Patel N, Dariolli R, Ng S, Aleman AG, Gong JQX, Lin HM, Rodr?guez M, Josowitz R, Sol-Church K, Gripp KW, Lin X, Song SC, Fishman GI, Sobie EA, Gelb BD. HRAS-Mutant Cardiomyocyte Model of Multifocal Atrial Tachycardia. Circ Arrhythm Electrophysiol. 2024 04; 17(4):e012022.

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Rodr?guez-Prados M, Huang KT, M?rta K, Paillard M, Csord?s G, Joseph SK, Hajn?czky G. MICU1 controls the sensitivity of the mitochondrial Ca2+ uniporter to activators and inhibitors. Cell Chem Biol. 2023 06 15; 30(6):606-617.e4.

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Tomar D, Thomas M, Garbincius JF, Kolmetzky DW, Salik O, Jadiya P, Joseph SK, Carpenter AC, Hajn?czky G, Elrod JW. MICU1 regulates mitochondrial cristae structure and function independently of the mitochondrial Ca2+ uniporter channel. Sci Signal. 2023 04 25; 16(782):eabi8948.

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Carlson EJ, Francis R, Liu Y, Li P, Lyon M, Santi CM, Hook DJ, Hawkinson JE, Georg GI. Discovery and Characterization of Multiple Classes of Human CatSper Blockers. ChemMedChem. 2022 08 03; 17(15):e202000499.

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Monteith AJ, Miller JM, Beavers WN, Maloney KN, Seifert EL, Hajnoczky G, Skaar EP. Mitochondrial Calcium Uniporter Affects Neutrophil Bactericidal Activity during Staphylococcus aureus Infection. Infect Immun. 2022 02 17; 90(2):e0055121.

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Young MP, Schug ZT, Booth DM, Yule DI, Mikoshiba K, Hajn?czky G, Joseph SK. Metabolic adaptation to the chronic loss of Ca2+ signaling induced by KO of IP3 receptors or the mitochondrial Ca2+?uniporter. J Biol Chem. 2022 01; 298(1):101436.

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Booth DM, V?rnai P, Joseph SK, Hajn?czky G. Oxidative bursts of single mitochondria mediate retrograde signaling toward the ER. Mol Cell. 2021 09 16; 81(18):3866-3876.e2.

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Bartok A, Weaver D, Golen?r T, Nichtova Z, Katona M, B?ns?ghi S, Alzayady KJ, Thomas VK, Ando H, Mikoshiba K, Joseph SK, Yule DI, Csord?s G, Hajn?czky G. IP3 receptor isoforms differently regulate ER-mitochondrial contacts and local calcium transfer. Nat Commun. 2019 08 19; 10(1):3726.

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Hurst S, Baggett A, Csordas G, Sheu SS. SPG7 targets the m-AAA protease complex to process MCU for uniporter assembly, Ca2+ influx, and regulation of mitochondrial permeability transition pore opening. J Biol Chem. 2019 07 12; 294(28):10807-10818.

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