"Scleritis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Refers to any inflammation of the sclera including episcleritis, a benign condition affecting only the episclera, which is generally short-lived and easily treated. Classic scleritis, on the other hand, affects deeper tissue and is characterized by higher rates of visual acuity loss and even mortality, particularly in necrotizing form. Its characteristic symptom is severe and general head pain. Scleritis has also been associated with systemic collagen disease. Etiology is unknown but is thought to involve a local immune response. Treatment is difficult and includes administration of anti-inflammatory and immunosuppressive agents such as corticosteroids. Inflammation of the sclera may also be secondary to inflammation of adjacent tissues, such as the conjunctiva.
| Descriptor ID |
D015423
|
| MeSH Number(s) |
C11.790.500
|
| Concept/Terms |
Necrotizing Scleritis- Necrotizing Scleritis
- Necrotizing Scleritides
- Scleritides, Necrotizing
- Scleritis, Necrotizing
|
Below are MeSH descriptors whose meaning is more general than "Scleritis".
Below are MeSH descriptors whose meaning is more specific than "Scleritis".
This graph shows the total number of publications written about "Scleritis" by people in this website by year, and whether "Scleritis" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 2 | 0 | 2 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 2 | 0 | 2 |
| 2007 | 1 | 1 | 2 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 2 | 0 | 2 |
| 2017 | 0 | 1 | 1 |
| 2018 | 2 | 0 | 2 |
| 2021 | 1 | 1 | 2 |
| 2023 | 2 | 0 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Scleritis" by people in Profiles.
-
Oh GJ, Khalili A, Hammersmith KM, Nagra PK, Rapuano CJ, Syed ZA. Determinants of Clinical Outcomes After Infectious Scleritis. Cornea. 2024 Jul 01; 43(7):828-834.
-
Wong JC, Savsani E, Mahmoudzadeh R, Salabati M, Razeghinejad R, Lee D, Shukla AG, Myers JS, Pro MJ, Moster MR, Dunn JP, Kolomeyer NN. Glaucoma Surgical Outcomes in Patients with a History of Scleritis. Ocul Immunol Inflamm. 2024 Aug; 32(6):987-993.
-
Yu J, Syed ZA, Rapuano CJ. Infectious Scleritis: Pathophysiology, Diagnosis, and Management. Eye Contact Lens. 2021 08 01; 47(8):434-441.
-
Kirino Y, Takase-Minegishi K, Tsuchida N, Hirahara L, Kunishita Y, Yoshimi R, Nakajima H. Tocilizumab in VEXAS relapsing polychondritis: a single-center pilot study in Japan. Ann Rheum Dis. 2021 11; 80(11):1501-1502.
-
Starr MR, Smith WM. Histoplasmosis Following Systemic Immunomodulatory Therapy for Ocular Inflammation. Am J Ophthalmol. 2019 02; 198:88-96.
-
O'Neil EC, Huang J, Suhler EB, Dunn JP, Perez VL, Gritz DC, McWilliams K, Peskin E, Ying GS, Bunya VY, Maguire MG, Kempen JH. Iontophoretic delivery of dexamethasone phosphate for non-infectious, non-necrotising anterior scleritis, dose-finding clinical trial. Br J Ophthalmol. 2018 08; 102(8):1011-1013.
-
LaMattina KC, Goldstein DA. Adalimumab for the treatment of uveitis. Expert Rev Clin Immunol. 2017 Mar; 13(3):181-188.
-
Dunn JP. Uveitis. Prim Care. 2015 Sep; 42(3):305-23.
-
Liu X, Kuriyan AE, Amescua G. A painful red eye. JAMA Ophthalmol. 2015 Jan; 133(1):95-6.
-
Reddy JC, Rapuano CJ, Eagle RC, Shields CL, Shields JA. Late-onset necrotizing scleritis due to pigmented mycetoma (dematiaceous fungi) in 2 cases. Cornea. 2013 Apr; 32(4):450-3.