Leukemia, Lymphocytic, Chronic, B-Cell

"Leukemia, Lymphocytic, Chronic, B-Cell" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A chronic leukemia characterized by abnormal B-lymphocytes and often generalized lymphadenopathy. In patients presenting predominately with blood and bone marrow involvement it is called chronic lymphocytic leukemia (CLL); in those predominately with enlarged lymph nodes it is called small lymphocytic lymphoma. These terms represent spectrums of the same disease.

Descriptor ID	D015451
MeSH Number(s)	C04.557.337.428.080.125 C15.604.515.560.080.125 C20.683.515.528.080.125
Concept/Terms	Leukemia, Lymphocytic, Chronic, B-Cell Leukemia, Lymphocytic, Chronic, B-Cell Leukemia, Lymphocytic, Chronic, B Cell Lymphoma, Lymphocytic, Well-Differentiated Lymphoma, Lymphoplasmacytoid, CLL Lymphoma, Small Lymphocytic Lymphocytic Lymphoma, Small Lymphocytic Lymphomas, Small Lymphomas, Small Lymphocytic Small Lymphocytic Lymphoma Small Lymphocytic Lymphomas Lymphoma, Small Lymphocytic, Plasmacytoid Lymphoma, Small-Cell Lymphoma, Small Cell Lymphomas, Small-Cell Small-Cell Lymphomas Lymphoplasmacytoid Lymphoma, CLL CLL Lymphoplasmacytoid Lymphoma CLL Lymphoplasmacytoid Lymphomas Lymphoma, CLL Lymphoplasmacytoid Lymphomas, CLL Lymphoplasmacytoid Lymphoplasmacytoid Lymphomas, CLL Small-Cell Lymphoma Small Cell Lymphoma Lymphoblastic Leukemia, Chronic Chronic Lymphoblastic Leukemia Chronic Lymphoblastic Leukemias Leukemias, Chronic Lymphoblastic Lymphoblastic Leukemias, Chronic Lymphocytic Leukemia, Chronic Lymphocytic Leukemia, Chronic, B Cell Lymphocytic Leukemia, Chronic, B-Cell Lymphocytic Lymphoma Lymphocytic Lymphomas Lymphomas, Lymphocytic Lymphocytic Lymphoma, Diffuse, Well Differentiated Lymphocytic Lymphoma, Diffuse, Well-Differentiated Lymphocytic Lymphoma, Well Differentiated Lymphocytic Lymphoma, Well-Differentiated Lymphocytic Lymphomas, Well-Differentiated Lymphoma, Well-Differentiated Lymphocytic Lymphomas, Well-Differentiated Lymphocytic Well-Differentiated Lymphocytic Lymphoma Well-Differentiated Lymphocytic Lymphomas Lymphoma, Lymphocytic Lymphoma, Lymphocytic, Diffuse, Well Differentiated B-Cell Chronic Lymphocytic Leukemia B Cell Chronic Lymphocytic Leukemia B-Cell Leukemia, Chronic B Cell Leukemia, Chronic B-Cell Leukemias, Chronic Chronic B-Cell Leukemia Chronic B-Cell Leukemias Leukemia, Chronic B-Cell Leukemias, Chronic B-Cell B-Cell Malignancy, Low-Grade B-Lymphocytic Leukemia, Chronic B Lymphocytic Leukemia, Chronic B-Lymphocytic Leukemias, Chronic Chronic B-Lymphocytic Leukemia Chronic B-Lymphocytic Leukemias Leukemia, Chronic B-Lymphocytic Leukemias, Chronic B-Lymphocytic Chronic Lymphocytic Leukemia Chronic Lymphocytic Leukemias Lymphocytic Leukemias, Chronic Diffuse Well-Differentiated Lymphocytic Lymphoma Diffuse Well Differentiated Lymphocytic Lymphoma Disrupted In B-Cell Malignancy Leukemia, B Cell, Chronic Leukemia, B-Cell, Chronic Leukemia, Chronic Lymphatic Leukemia, Chronic Lymphocytic Leukemia, Chronic Lymphocytic, B-Cell Leukemia, Lymphoblastic, Chronic Leukemia, Lymphocytic, Chronic Lymphoma, Lymphocytic, Diffuse, Well-Differentiated Lymphoma, Lymphocytic, Well Differentiated

Below are MeSH descriptors whose meaning is more general than "Leukemia, Lymphocytic, Chronic, B-Cell".

Diseases [C]
Neoplasms [C04]
Neoplasms by Histologic Type [C04.557]
Leukemia [C04.557.337]
Leukemia, Lymphoid [C04.557.337.428]
Leukemia, B-Cell [C04.557.337.428.080]
Leukemia, Lymphocytic, Chronic, B-Cell [C04.557.337.428.080.125]
Hemic and Lymphatic Diseases [C15]
Lymphatic Diseases [C15.604]
Lymphoproliferative Disorders [C15.604.515]
Leukemia, Lymphoid [C15.604.515.560]
Leukemia, B-Cell [C15.604.515.560.080]
Leukemia, Lymphocytic, Chronic, B-Cell [C15.604.515.560.080.125]
Immune System Diseases [C20]
Immunoproliferative Disorders [C20.683]
Lymphoproliferative Disorders [C20.683.515]
Leukemia, Lymphoid [C20.683.515.528]
Leukemia, B-Cell [C20.683.515.528.080]
Leukemia, Lymphocytic, Chronic, B-Cell [C20.683.515.528.080.125]

Below are MeSH descriptors whose meaning is related to "Leukemia, Lymphocytic, Chronic, B-Cell".

Below are MeSH descriptors whose meaning is more specific than "Leukemia, Lymphocytic, Chronic, B-Cell".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Leukemia, Lymphocytic, Chronic, B-Cell" by people in this website by year, and whether "Leukemia, Lymphocytic, Chronic, B-Cell" was a major or minor topic of these publications.

Bar chart showing 75 publications over 27 distinct years, with a maximum of 8 publications in 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
1999	1	0	1
2000	1	0	1
2001	0	1	1
2002	1	0	1
2003	1	0	1
2004	2	0	2
2005	2	0	2
2006	3	1	4
2007	1	0	1
2008	3	1	4
2009	3	1	4
2010	3	1	4
2011	4	0	4
2012	1	0	1
2013	4	1	5
2014	1	0	1
2015	3	1	4
2016	4	0	4
2017	8	0	8
2018	4	0	4
2019	2	2	4
2020	1	0	1
2021	5	1	6
2022	3	0	3
2023	1	0	1
2024	2	0	2

Below are the most recent publications written about "Leukemia, Lymphocytic, Chronic, B-Cell" by people in Profiles.

Shi C, Lytle A, Milman T, Penne R, Bagg A. Composite Histiocytic Sarcoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma of the Ocular Adnexa. Ophthalmic Plast Reconstr Surg. 2024 Sep-Oct 01; 40(5):e156-e161.

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Wierda WG, Brown J, Abramson JS, Awan F, Bilgrami SF, Bociek G, Brander D, Cortese M, Cripe L, Davis RS, Eradat H, Fakhri B, Fletcher CD, Gaballa S, Hamid MS, Hill B, Kaesberg P, Kahl B, Kamdar M, Kipps TJ, Ma S, Mosse C, Nakhoda S, Parikh S, Schorr A, Schuster S, Seshadri M, Siddiqi T, Stephens DM, Thompson M, Ujjani C, Valdez R, Wagner-Johnston N, Woyach JA, Sundar H, Dwyer M. Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 2.2024, NCCN Clinical Practice Guidelines in Oncology J Natl Compr Canc Netw. 2024 04; 22(3):175-204.

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Siddiqi T, Maloney DG, Kenderian SS, Brander DM, Dorritie K, Soumerai J, Riedell PA, Shah NN, Nath R, Fakhri B, Stephens DM, Ma S, Feldman T, Solomon SR, Schuster SJ, Perna SK, Tuazon SA, Ou SS, Papp E, Peiser L, Chen Y, Wierda WG. Lisocabtagene maraleucel in chronic lymphocytic leukaemia and small lymphocytic lymphoma (TRANSCEND CLL 004): a multicentre, open-label, single-arm, phase 1-2 study. Lancet. 2023 08 19; 402(10402):641-654.

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Jung B, Ferrer G, Chiu PY, Aslam R, Ng A, Palacios F, Wysota M, Cardillo M, Kolitz JE, Allen SL, Barrientos JC, Rai KR, Chiorazzi N, Sherry B. Activated CLL cells regulate IL-17F-producing Th17 cells in miR155-dependent and outcome-specific manners. JCI Insight. 2022 06 22; 7(12).

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Wierda WG, Brown J, Abramson JS, Awan F, Bilgrami SF, Bociek G, Brander D, Chanan-Khan AA, Coutre SE, Davis RS, Eradat H, Fletcher CD, Gaballa S, Ghobadi A, Hamid MS, Hernandez-Ilizaliturri F, Hill B, Kaesberg P, Kamdar M, Kaplan LD, Khan N, Kipps TJ, Ma S, Mato A, Mosse C, Schuster S, Siddiqi T, Stephens DM, Ujjani C, Wagner-Johnston N, Woyach JA, Ye JC, Dwyer MA, Sundar H. NCCN Guidelines? Insights: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 3.2022. J Natl Compr Canc Netw. 2022 06; 20(6):622-634.

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Snow Z, Jones LS, Piraino J, Sterling M. Chronic lymphocytic leukemia/small lymphocytic lymphoma presenting as acute renal failure. Can J Urol. 2022 02; 29(1):11036-11039.

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Yang Y, Gergis U, Carabasi M, Filicko-O'Hara J, Wagner JL, O'Hara W, Binder A, Alpdogan O, Martinez-Outschoorn U, Porcu P, Flomenberg N, Grosso D. The Two-Step Allogeneic Stem Cell Transplantation Approach Results in Rapid Engraftment and Excellent Outcomes in Patients with Lymphoid Malignancies. Transplant Cell Ther. 2022 03; 28(3):159.e1-159.e5.

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Kim HT, Baker PO, Parry E, Davids M, Alyea EP, Ho VT, Cutler C, Koreth J, Gooptu M, Romee R, Nikiforow S, Antin JH, Ritz J, Soiffer RJ, Wu CJ, Brown JR. Allogeneic hematopoietic cell transplantation outcomes in patients with Richter's transformation. Haematologica. 2021 12 01; 106(12):3219-3222.

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Stephens DM, Boucher K, Kander E, Parikh SA, Parry EM, Shadman M, Pagel JM, Cooperrider J, Rhodes J, Mato A, Winter A, Hill B, Gaballa S, Danilov A, Phillips T, Brander DM, Smith SM, Davids M, Rogers K, Glenn MJ, Byrd JC. Hodgkin lymphoma arising in patients with chronic lymphocytic leukemia: outcomes from a large multi-center collaboration. Haematologica. 2021 11 01; 106(11):2845-2852.

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Gaballa S, Pinilla-Ibarz J. BTK Inhibitors in Chronic Lymphocytic Leukemia. Curr Hematol Malig Rep. 2021 10; 16(5):422-432.

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