2-Amino-5-phosphonovalerate
"2-Amino-5-phosphonovalerate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.
| Descriptor ID |
D015763
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| MeSH Number(s) |
D12.125.070.950.100 D12.125.740.025
|
| Concept/Terms |
2-Amino-5-phosphonovalerate- 2-Amino-5-phosphonovalerate
- 2 Amino 5 phosphonovalerate
- 5-Phosphononorvaline
- 5 Phosphononorvaline
- 2-Amino-5-phosphonovaleric Acid
- 2 Amino 5 phosphonovaleric Acid
- 2-APV
- 2-Amino-5-phosphonopentanoate
- 2 Amino 5 phosphonopentanoate
- 2-Amino-5-phosphonopentanoic Acid
- 2 Amino 5 phosphonopentanoic Acid
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Below are MeSH descriptors whose meaning is more general than "2-Amino-5-phosphonovalerate".
Below are MeSH descriptors whose meaning is more specific than "2-Amino-5-phosphonovalerate".
This graph shows the total number of publications written about "2-Amino-5-phosphonovalerate" by people in this website by year, and whether "2-Amino-5-phosphonovalerate" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
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Below are the most recent publications written about "2-Amino-5-phosphonovalerate" by people in Profiles.
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Ramakers GM, Pasinelli P, van Beest M, van der Slot A, Gispen WH, De Graan PN. Activation of pre- and postsynaptic protein kinase C during tetraethylammonium-induced long-term potentiation in the CA1 field of the hippocampus. Neurosci Lett. 2000 May 26; 286(1):53-6.
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Mondadori C, Gentsch C, Hengerer B, Ducret T, Borkowski J, Racine A, Lederer R, Haeusler A. Pretreatment with aldosterone or corticosterone blocks the memory-enhancing effects of nimodipine, captopril, CGP 37,849, and strychnine in mice. Psychopharmacology (Berl). 1992; 109(4):383-9.
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Paton JF, Rogers WT, Schwaber JS. The ventrolateral medulla as a source of synaptic drive to rhythmically firing neurons in the cardiovascular nucleus tractus solitarius of the rat. Brain Res. 1991 Oct 11; 561(2):217-29.
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Paton JF, Rogers WT, Schwaber JS. Tonically rhythmic neurons within a cardiorespiratory region of the nucleus tractus solitarii of the rat. J Neurophysiol. 1991 Sep; 66(3):824-38.