Macrophage Colony-Stimulating Factor

"Macrophage Colony-Stimulating Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A mononuclear phagocyte colony-stimulating factor (M-CSF) synthesized by mesenchymal cells. The compound stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series. M-CSF is a disulfide-bonded glycoprotein dimer with a MW of 70 kDa. It binds to a specific high affinity receptor (RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR).

Descriptor ID	D016173
MeSH Number(s)	D12.644.276.374.410.240.500 D12.776.395.240.500 D12.776.467.374.410.240.500 D23.529.374.410.240.500
Concept/Terms	Macrophage Colony-Stimulating Factor Macrophage Colony-Stimulating Factor M-CSF CSF-1 CSF-M Colony-Stimulating Factor 1 Colony Stimulating Factor 1 Colony-Stimulating Factor, Macrophage Colony Stimulating Factor, Macrophage

Below are MeSH descriptors whose meaning is more general than "Macrophage Colony-Stimulating Factor".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Cytokines [D12.644.276.374]
Hematopoietic Cell Growth Factors [D12.644.276.374.410]
Colony-Stimulating Factors [D12.644.276.374.410.240]
Macrophage Colony-Stimulating Factor [D12.644.276.374.410.240.500]
Proteins [D12.776]
Glycoproteins [D12.776.395]
Colony-Stimulating Factors [D12.776.395.240]
Macrophage Colony-Stimulating Factor [D12.776.395.240.500]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Cytokines [D12.776.467.374]
Hematopoietic Cell Growth Factors [D12.776.467.374.410]
Colony-Stimulating Factors [D12.776.467.374.410.240]
Macrophage Colony-Stimulating Factor [D12.776.467.374.410.240.500]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Cytokines [D23.529.374]
Hematopoietic Cell Growth Factors [D23.529.374.410]
Colony-Stimulating Factors [D23.529.374.410.240]
Macrophage Colony-Stimulating Factor [D23.529.374.410.240.500]

Below are MeSH descriptors whose meaning is related to "Macrophage Colony-Stimulating Factor".

Below are MeSH descriptors whose meaning is more specific than "Macrophage Colony-Stimulating Factor".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Macrophage Colony-Stimulating Factor" by people in this website by year, and whether "Macrophage Colony-Stimulating Factor" was a major or minor topic of these publications.

Bar chart showing 9 publications over 7 distinct years, with a maximum of 2 publications in 2003 and 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2003	1	1	2
2004	0	1	1
2005	2	0	2
2015	0	1	1
2019	0	1	1
2023	0	1	1

Below are the most recent publications written about "Macrophage Colony-Stimulating Factor" by people in Profiles.

Efe G, Dunbar KJ, Sugiura K, Cunningham K, Carcamo S, Karaiskos S, Tang Q, Cruz-Acu?a R, Resnick-Silverman L, Peura J, Lu C, Hasson D, Klein-Szanto AJ, Taylor AM, Manfredi JJ, Prives C, Rustgi AK. p53 Gain-of-Function Mutation Induces Metastasis via BRD4-Dependent CSF-1 Expression. Cancer Discov. 2023 12 12; 13(12):2632-2651.

View in: PubMed
DiMeglio M, Furey W, Hajj J, Lindekens J, Patel S, Acker M, Bavaria J, Szeto WY, Atluri P, Haber M, Diaz-Arrastia R, Laudanski K. Observational study of long-term persistent elevation of neurodegeneration markers after cardiac surgery. Sci Rep. 2019 05 09; 9(1):7177.

View in: PubMed
Meijome TE, Ekwealor JTB, Hooker RA, Cheng YH, Ciovacco WA, Balamohan SM, Srinivasan TL, Chitteti BR, Eleniste PP, Horowitz MC, Srour EF, Bruzzaniti A, Fuchs RK, Kacena MA. C-Mpl Is Expressed on Osteoblasts and Osteoclasts and Is Important in Regulating Skeletal Homeostasis. J Cell Biochem. 2016 04; 117(4):959-69.

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Bonfield TL, Swaisgood CM, Barna BP, Farver CF, Kavuru MS, Thomassen MJ. Elevated gelatinase activity in pulmonary alveolar proteinosis: role of macrophage-colony stimulating factor. J Leukoc Biol. 2006 Jan; 79(1):133-9.

View in: PubMed
Nakao K, Kubota S, Doi H, Eguchi T, Oka M, Fujisawa T, Nishida T, Takigawa M. Collaborative action of M-CSF and CTGF/CCN2 in articular chondrocytes: possible regenerative roles in articular cartilage metabolism. Bone. 2005 May; 36(5):884-92.

View in: PubMed
Meaney S, Bonfield TL, Hansson M, Babiker A, Kavuru MS, Thomassen MJ. Serum cholestenoic acid as a potential marker of pulmonary cholesterol homeostasis: increased levels in patients with pulmonary alveolar proteinosis. J Lipid Res. 2004 Dec; 45(12):2354-60.

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Bruhns P, Samuelsson A, Pollard JW, Ravetch JV. Colony-stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune disease. Immunity. 2003 Apr; 18(4):573-81.

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Hansson M, Ellis E, Hunt MC, Schmitz G, Babiker A. Marked induction of sterol 27-hydroxylase activity and mRNA levels during differentiation of human cultured monocytes into macrophages. Biochim Biophys Acta. 2003 Feb 17; 1593(2-3):283-9.

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Bonfield TL, Russell D, Burgess S, Malur A, Kavuru MS, Thomassen MJ. Autoantibodies against granulocyte macrophage colony-stimulating factor are diagnostic for pulmonary alveolar proteinosis. Am J Respir Cell Mol Biol. 2002 Oct; 27(4):481-6.

View in: PubMed

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