Guanosine 5'-O-(3-Thiotriphosphate)
"Guanosine 5'-O-(3-Thiotriphosphate)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Guanosine 5'-(trihydrogen diphosphate), monoanhydride with phosphorothioic acid. A stable GTP analog which enjoys a variety of physiological actions such as stimulation of guanine nucleotide-binding proteins, phosphoinositide hydrolysis, cyclic AMP accumulation, and activation of specific proto-oncogenes.
| Descriptor ID |
D016244
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| MeSH Number(s) |
D02.886.765.380 D13.695.667.454.504.380 D13.695.827.426.504.380 D13.695.900.380
|
| Concept/Terms |
Guanosine 5'-O-(3-Thiotriphosphate)- Guanosine 5'-O-(3-Thiotriphosphate)
- GTP gamma S
- gamma S, GTP
- GTPgammaS
- Guanosine 5'-(gamma-S)Triphosphate
- gamma-Thio-GTP
- gamma Thio GTP
- Guanosine 5'-(3-O-Thio)Triphosphate
|
Below are MeSH descriptors whose meaning is more general than "Guanosine 5'-O-(3-Thiotriphosphate)".
Below are MeSH descriptors whose meaning is more specific than "Guanosine 5'-O-(3-Thiotriphosphate)".
This graph shows the total number of publications written about "Guanosine 5'-O-(3-Thiotriphosphate)" by people in this website by year, and whether "Guanosine 5'-O-(3-Thiotriphosphate)" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 3 | 3 |
| 2010 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 2 | 0 | 2 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Guanosine 5'-O-(3-Thiotriphosphate)" by people in Profiles.
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Lapadula D, Farias E, Randolph CE, Purwin TJ, McGrath D, Charpentier TH, Zhang L, Wu S, Terai M, Sato T, Tall GG, Zhou N, Wedegaertner PB, Aplin AE, Aguirre-Ghiso J, Benovic JL. Effects of Oncogenic Gaq and Ga11 Inhibition by FR900359 in Uveal Melanoma. Mol Cancer Res. 2019 04; 17(4):963-973.
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Borgmann-Winter KE, Wang HY, Ray R, Willis BR, Moberg PJ, Rawson NE, Gur RE, Turetsky BI, Hahn CG. Altered G Protein Coupling in Olfactory Neuroepithelial Cells From Patients With Schizophrenia. Schizophr Bull. 2016 Mar; 42(2):377-85.
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Manning DR, Shen F, Riobo NA. Evaluating the Activity of Smoothened Toward G Proteins Using [?5S]Guanosine 5'-(3-O-thio)triphosphate ([?5S]GTP?S). Methods Mol Biol. 2015; 1322:35-44.
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Shen F, Cheng L, Douglas AE, Riobo NA, Manning DR. Smoothened is a fully competent activator of the heterotrimeric G protein G(i). Mol Pharmacol. 2013 Mar; 83(3):691-7.
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Kim FJ, Kovalyshyn I, Burgman M, Neilan C, Chien CC, Pasternak GW. Sigma 1 receptor modulation of G-protein-coupled receptor signaling: potentiation of opioid transduction independent from receptor binding. Mol Pharmacol. 2010 Apr; 77(4):695-703.
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Riobo NA, Saucy B, Dilizio C, Manning DR. Activation of heterotrimeric G proteins by Smoothened. Proc Natl Acad Sci U S A. 2006 Aug 15; 103(33):12607-12.
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Frankland S, Adisa A, Horrocks P, Taraschi TF, Schneider T, Elliott SR, Rogerson SJ, Knuepfer E, Cowman AF, Newbold CI, Tilley L. Delivery of the malaria virulence protein PfEMP1 to the erythrocyte surface requires cholesterol-rich domains. Eukaryot Cell. 2006 May; 5(5):849-60.
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Navenot JM, Wang ZX, Peiper SC. Characterization of constitutively active mutants of G protein-coupled receptors. Methods Mol Biol. 2006; 332:129-39.
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Stevenson AS, Matthew JD, Eto M, Luo S, Somlyo AP, Somlyo AV. Uncoupling of GPCR and RhoA-induced Ca2+-sensitization of chicken amnion smooth muscle lacking CPI-17. FEBS Lett. 2004 Dec 03; 578(1-2):73-9.
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Alvarez Arias D, Navenot JM, Zhang WB, Broach J, Peiper SC. Constitutive activation of CCR5 and CCR2 induced by conformational changes in the conserved TXP motif in transmembrane helix 2. J Biol Chem. 2003 Sep 19; 278(38):36513-21.