Guanosine 5'-O-(3-Thiotriphosphate)

"Guanosine 5'-O-(3-Thiotriphosphate)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Guanosine 5'-(trihydrogen diphosphate), monoanhydride with phosphorothioic acid. A stable GTP analog which enjoys a variety of physiological actions such as stimulation of guanine nucleotide-binding proteins, phosphoinositide hydrolysis, cyclic AMP accumulation, and activation of specific proto-oncogenes.

Descriptor ID	D016244
MeSH Number(s)	D02.886.765.380 D13.695.667.454.504.380 D13.695.827.426.504.380 D13.695.900.380
Concept/Terms	Guanosine 5'-O-(3-Thiotriphosphate) Guanosine 5'-O-(3-Thiotriphosphate) GTP gamma S gamma S, GTP GTPgammaS Guanosine 5'-(gamma-S)Triphosphate gamma-Thio-GTP gamma Thio GTP Guanosine 5'-(3-O-Thio)Triphosphate

Below are MeSH descriptors whose meaning is more general than "Guanosine 5'-O-(3-Thiotriphosphate)".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Sulfur Compounds [D02.886]
Thionucleotides [D02.886.765]
Guanosine 5'-O-(3-Thiotriphosphate) [D02.886.765.380]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Nucleotides [D13.695]
Purine Nucleotides [D13.695.667]
Guanine Nucleotides [D13.695.667.454]
Guanosine Triphosphate [D13.695.667.454.504]
Guanosine 5'-O-(3-Thiotriphosphate) [D13.695.667.454.504.380]
Ribonucleotides [D13.695.827]
Guanine Nucleotides [D13.695.827.426]
Guanosine Triphosphate [D13.695.827.426.504]
Guanosine 5'-O-(3-Thiotriphosphate) [D13.695.827.426.504.380]
Thionucleotides [D13.695.900]
Guanosine 5'-O-(3-Thiotriphosphate) [D13.695.900.380]

Below are MeSH descriptors whose meaning is related to "Guanosine 5'-O-(3-Thiotriphosphate)".

Below are MeSH descriptors whose meaning is more specific than "Guanosine 5'-O-(3-Thiotriphosphate)".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Guanosine 5'-O-(3-Thiotriphosphate)" by people in this website by year, and whether "Guanosine 5'-O-(3-Thiotriphosphate)" was a major or minor topic of these publications.

Bar chart showing 4 publications over 4 distinct years, with a maximum of 1 publications in 2002 and 2004 and 2006 and 2018

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
2002	1	1
2004	1	1
2006	1	1
2018	1	1

Below are the most recent publications written about "Guanosine 5'-O-(3-Thiotriphosphate)" by people in Profiles.

Lapadula D, Farias E, Randolph CE, Purwin TJ, McGrath D, Charpentier TH, Zhang L, Wu S, Terai M, Sato T, Tall GG, Zhou N, Wedegaertner PB, Aplin AE, Aguirre-Ghiso J, Benovic JL. Effects of Oncogenic Gaq and Ga11 Inhibition by FR900359 in Uveal Melanoma. Mol Cancer Res. 2019 04; 17(4):963-973.

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Frankland S, Adisa A, Horrocks P, Taraschi TF, Schneider T, Elliott SR, Rogerson SJ, Knuepfer E, Cowman AF, Newbold CI, Tilley L. Delivery of the malaria virulence protein PfEMP1 to the erythrocyte surface requires cholesterol-rich domains. Eukaryot Cell. 2006 May; 5(5):849-60.

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Stevenson AS, Matthew JD, Eto M, Luo S, Somlyo AP, Somlyo AV. Uncoupling of GPCR and RhoA-induced Ca2+-sensitization of chicken amnion smooth muscle lacking CPI-17. FEBS Lett. 2004 Dec 03; 578(1-2):73-9.

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Wang H, Eto M, Steers WD, Somlyo AP, Somlyo AV. RhoA-mediated Ca2+ sensitization in erectile function. J Biol Chem. 2002 Aug 23; 277(34):30614-21.

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Zhang J, Zhang J, Benovic JL, Sugai M, Wetzker R, Gout I, Rittenhouse SE. Sequestration of a G-protein beta gamma subunit or ADP-ribosylation of Rho can inhibit thrombin-induced activation of platelet phosphoinositide 3-kinases. J Biol Chem. 1995 Mar 24; 270(12):6589-94.

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Ramkumar V, Kwatra M, Benovic JL, Stiles GL, Stilesa GL. Functional consequences of A1 adenosine-receptor phosphorylation by the beta-adrenergic receptor kinase. Biochim Biophys Acta. 1993 Oct 07; 1179(1):89-97.

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Krupinski J, Rajaram R, Lakonishok M, Benovic JL, Cerione RA. Insulin-dependent phosphorylation of GTP-binding proteins in phospholipid vesicles. J Biol Chem. 1988 Sep 05; 263(25):12333-41.

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Senogles SE, Benovic JL, Amlaiky N, Unson C, Milligan G, Vinitsky R, Spiegel AM, Caron MG. The D2-dopamine receptor of anterior pituitary is functionally associated with a pertussis toxin-sensitive guanine nucleotide binding protein. J Biol Chem. 1987 Apr 05; 262(10):4860-7.

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Cerione RA, Staniszewski C, Benovic JL, Lefkowitz RJ, Caron MG, Gierschik P, Somers R, Spiegel AM, Codina J, Birnbaumer L. Specificity of the functional interactions of the beta-adrenergic receptor and rhodopsin with guanine nucleotide regulatory proteins reconstituted in phospholipid vesicles. J Biol Chem. 1985 Feb 10; 260(3):1493-500.

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Waldman SA, Lewicki JA, Chang LY, Murad F. Highly purified particulate guanylate cyclase from rat lung: characterization and comparison with soluble guanylate cyclase. Mol Cell Biochem. 1983; 57(2):155-66.

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