"Iloprost" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An eicosanoid, derived from the cyclooxygenase pathway of arachidonic acid metabolism. It is a stable and synthetic analog of EPOPROSTENOL, but with a longer half-life than the parent compound. Its actions are similar to prostacyclin. Iloprost produces vasodilation and inhibits platelet aggregation.
| Descriptor ID |
D016285
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| MeSH Number(s) |
D10.251.355.255.550.775.125 D23.469.050.175.725.775.125 D23.469.700.275
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Iloprost".
Below are MeSH descriptors whose meaning is more specific than "Iloprost".
This graph shows the total number of publications written about "Iloprost" by people in this website by year, and whether "Iloprost" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
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Below are the most recent publications written about "Iloprost" by people in Profiles.
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Wigley FM, Korn JH, Csuka ME, Medsger TA, Rothfield NF, Ellman M, Martin R, Collier DH, Weinstein A, Furst DE, Jimenez SA, Mayes MD, Merkel PA, Gruber B, Kaufman L, Varga J, Bell P, Kern J, Marrott P, White B, Simms RW, Phillips AC, Seibold JR. Oral iloprost treatment in patients with Raynaud's phenomenon secondary to systemic sclerosis: a multicenter, placebo-controlled, double-blind study. Arthritis Rheum. 1998 Apr; 41(4):670-7.
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Wigley FM, Wise RA, Seibold JR, McCloskey DA, Kujala G, Medsger TA, Steen VD, Varga J, Jimenez S, Mayes M, Clements PJ, Weiner SR, Porter J, Ellman M, Wise C, Kaufman LD, Williams J, Dole W. Intravenous iloprost infusion in patients with Raynaud phenomenon secondary to systemic sclerosis. A multicenter, placebo-controlled, double-blind study. Ann Intern Med. 1994 Feb 01; 120(3):199-206.
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Appasamy PM, Pendino K, Schmidt RR, Chepenik KP, Prystowsky MB, Goldowitz D. Expression of prostaglandin G/H synthase (cyclooxygenase) during murine fetal thymic development. Cell Immunol. 1991 Oct 15; 137(2):341-57.
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Levitt MA, Dryjski M, Tluczek J, Bjornsson TD. Evaluation of a prostacyclin analog, iloprost, and a thromboxane A2 receptor antagonist, daltroban, in experimental intimal hyperplasia. Prostaglandins. 1991 Jan; 41(1):1-6.