"HIV Long Terminal Repeat" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Regulatory sequences important for viral replication that are located on each end of the HIV genome. The LTR includes the HIV ENHANCER, promoter, and other sequences. Specific regions in the LTR include the negative regulatory element (NRE), NF-kappa B binding sites , Sp1 binding sites, TATA BOX, and trans-acting responsive element (TAR). The binding of both cellular and viral proteins to these regions regulates HIV transcription.
| Descriptor ID |
D016325
|
| MeSH Number(s) |
G02.111.570.080.708.850.400 G05.360.080.708.850.400
|
| Concept/Terms |
HIV Long Terminal Repeat- HIV Long Terminal Repeat
- LTR, Human Immunodeficiency Virus
- Human Immunodeficiency Virus LTR
- Long Terminal Repeat, HIV
- Human Immunodeficiency Virus Long Terminal Repeat
Trans-Acting Responsive Region, HIV- Trans-Acting Responsive Region, HIV
- Trans Acting Responsive Region, HIV
- HIV Trans-Acting Responsive Region
- HIV Trans Acting Responsive Region
- Trans-Activation Responsive Element, HIV
- Trans Activation Responsive Element, HIV
- Trans-Activation Responsive Region, HIV
- Trans Activation Responsive Region, HIV
- TAR Element, HIV
- HIV TAR Element
- HIV TAR Elements
- TAR Elements, HIV
Sp1-Binding Site, HIV- Sp1-Binding Site, HIV
- Sp1 Binding Site, HIV
- HIV Sp1-Binding Site
- HIV Sp1 Binding Site
- HIV Sp1-Binding Sites
- Sp1-Binding Sites, HIV
|
Below are MeSH descriptors whose meaning is more general than "HIV Long Terminal Repeat".
Below are MeSH descriptors whose meaning is more specific than "HIV Long Terminal Repeat".
This graph shows the total number of publications written about "HIV Long Terminal Repeat" by people in this website by year, and whether "HIV Long Terminal Repeat" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 2 | 3 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 3 | 0 | 3 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 0 | 2 | 2 |
| 2018 | 1 | 0 | 1 |
| 2020 | 0 | 2 | 2 |
| 2021 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "HIV Long Terminal Repeat" by people in Profiles.
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Sharma AL, Tyagi P, Khumallambam M, Tyagi M. Cocaine-Induced DNA-Dependent Protein Kinase Relieves RNAP II Pausing by Promoting TRIM28 Phosphorylation and RNAP II Hyperphosphorylation to Enhance HIV Transcription. Cells. 2024 11 23; 13(23).
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Hokello J, Lakhikumar Sharma A, Tyagi M. AP-1 and NF-?B synergize to transcriptionally activate latent HIV upon T-cell receptor activation. FEBS Lett. 2021 03; 595(5):577-594.
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Sharma AL, Hokello J, Sonti S, Zicari S, Sun L, Alqatawni A, Bukrinsky M, Simon G, Chauhan A, Daniel R, Tyagi M. CBF-1 Promotes the Establishment and Maintenance of HIV Latency by Recruiting Polycomb Repressive Complexes, PRC1 and PRC2, at HIV LTR. Viruses. 2020 09 18; 12(9).
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Hokello J, Sharma AL, Tyagi M. Efficient Non-Epigenetic Activation of HIV Latency through the T-Cell Receptor Signalosome. Viruses. 2020 08 08; 12(8).
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Cannon L, Vargas-Garcia CA, Jagarapu A, Piovoso MJ, Zurakowski R. HIV 2-LTR experiment design optimization. PLoS One. 2018; 13(11):e0206700.
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Tyagi M, Weber J, Bukrinsky M, Simon GL. The effects of cocaine on HIV transcription. J Neurovirol. 2016 06; 22(3):261-74.
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Sahu G, Farley K, El-Hage N, Aiamkitsumrit B, Fassnacht R, Kashanchi F, Ochem A, Simon GL, Karn J, Hauser KF, Tyagi M. Cocaine promotes both initiation and elongation phase of HIV-1 transcription by activating NF-?B and MSK1 and inducing selective epigenetic modifications at HIV-1 LTR. Virology. 2015 Sep; 483:185-202.
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Cardozo EF, Luo R, Piovoso MJ, Zurakowski R. Spatial modeling of HIV cryptic viremia and 2-LTR formation during raltegravir intensification. J Theor Biol. 2014 Mar 21; 345:61-9.
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Blazkova J, Murray D, Justement JS, Funk EK, Nelson AK, Moir S, Chun TW, Fauci AS. Paucity of HIV DNA methylation in latently infected, resting CD4+ T cells from infected individuals receiving antiretroviral therapy. J Virol. 2012 May; 86(9):5390-2.
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Van Duyne R, Guendel I, Narayanan A, Gregg E, Shafagati N, Tyagi M, Easley R, Klase Z, Nekhai S, Kehn-Hall K, Kashanchi F. Varying modulation of HIV-1 LTR activity by Baf complexes. J Mol Biol. 2011 Aug 19; 411(3):581-96.