"Neurofibromatosis 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autosomal dominant disorder characterized by a high incidence of bilateral acoustic neuromas as well as schwannomas (NEURILEMMOMA) of other cranial and peripheral nerves, and other benign intracranial tumors including meningiomas, ependymomas, spinal neurofibromas, and gliomas. The disease has been linked to mutations of the NF2 gene (GENES, NEUROFIBROMATOSIS 2) on chromosome 22 (22q12) and usually presents clinically in the first or second decade of life.
| Descriptor ID |
D016518
|
| MeSH Number(s) |
C04.557.465.625.650.595.610.500 C04.557.580.600.580.590.655 C04.557.580.600.610.595.610.500 C04.700.645.655 C09.218.807.800.675.500 C09.647.675.500 C10.292.225.750.500 C10.292.910.600.500 C10.562.600.750 C10.574.500.549.700 C16.320.400.560.700 C16.320.700.645.655
|
| Concept/Terms |
Neurofibromatosis 2- Neurofibromatosis 2
- Neurofibromatosis, Central, NF2
- Neurofibromatosis, Central, NF 2
- Bilateral Acoustic Neurofibromatosis
- Acoustic Neurofibromatoses, Bilateral
- Acoustic Neurofibromatosis, Bilateral
- Bilateral Acoustic Neurofibromatoses
- Neurofibromatoses, Bilateral Acoustic
- Neurofibromatosis, Bilateral Acoustic
- Neurofibromatosis II
- Neurofibromatosis IIs
- Neurofibromatosis, central type
- Neurofibromatosis Type 2
- Neurofibromatosis, Type II
- Neurofibromatoses, Type II
- Type II Neurofibromatoses
- Type II Neurofibromatosis
- Neurofibromatosis, Type 2
- Neurofibromatoses, Type 2
- Type 2 Neurofibromatoses
- Type 2 Neurofibromatosis
- NF2 (Neurofibromatosis 2)
- NF2s (Neurofibromatosis 2)
- Neurofibromatosis, Central NF2
- Central NF2 Neurofibromatoses
- Central NF2 Neurofibromatosis
- Neurofibromatoses, Central NF2
- Central Neurofibromatosis
- Central Neurofibromatoses
- Neurofibromatoses, Central
- Neurofibromatosis, Central
- Neurofibromatosis, Acoustic, Bilateral
- Neurofibromatosis Type II
Neuroma, Acoustic, Bilateral- Neuroma, Acoustic, Bilateral
- Acoustic Neurinoma, Bilateral
- Acoustic Neurinomas, Bilateral
- Bilateral Acoustic Neurinoma
- Bilateral Acoustic Neurinomas
- Neurinoma, Bilateral Acoustic
- Neurinomas, Bilateral Acoustic
Schwannoma, Acoustic, Bilateral- Schwannoma, Acoustic, Bilateral
- Acoustic Schwannomas, Bilateral
- Acoustic Schwannoma, Bilateral
- Bilateral Acoustic Schwannoma
- Bilateral Acoustic Schwannomas
- Schwannoma, Bilateral Acoustic
- Schwannomas, Bilateral Acoustic
Familial Acoustic Neuromas- Familial Acoustic Neuromas
- Acoustic Neuroma, Familial
- Acoustic Neuromas, Familial
- Familial Acoustic Neuroma
- Neuroma, Familial Acoustic
- Neuromas, Familial Acoustic
|
Below are MeSH descriptors whose meaning is more general than "Neurofibromatosis 2".
- Diseases [C]
- Neoplasms [C04]
- Neoplasms by Histologic Type [C04.557]
- Neoplasms, Germ Cell and Embryonal [C04.557.465]
- Neuroectodermal Tumors [C04.557.465.625]
- Neuroendocrine Tumors [C04.557.465.625.650]
- Neurilemmoma [C04.557.465.625.650.595]
- Neuroma, Acoustic [C04.557.465.625.650.595.610]
- Neurofibromatosis 2 [C04.557.465.625.650.595.610.500]
- Neoplasms, Nerve Tissue [C04.557.580]
- Nerve Sheath Neoplasms [C04.557.580.600]
- Neurofibroma [C04.557.580.600.580]
- Neurofibromatoses [C04.557.580.600.580.590]
- Neurofibromatosis 2 [C04.557.580.600.580.590.655]
- Neuroma [C04.557.580.600.610]
- Neurilemmoma [C04.557.580.600.610.595]
- Neuroma, Acoustic [C04.557.580.600.610.595.610]
- Neurofibromatosis 2 [C04.557.580.600.610.595.610.500]
- Neoplastic Syndromes, Hereditary [C04.700]
- Neurofibromatoses [C04.700.645]
- Neurofibromatosis 2 [C04.700.645.655]
- Otorhinolaryngologic Diseases [C09]
- Ear Diseases [C09.218]
- Retrocochlear Diseases [C09.218.807]
- Vestibulocochlear Nerve Diseases [C09.218.807.800]
- Neuroma, Acoustic [C09.218.807.800.675]
- Neurofibromatosis 2 [C09.218.807.800.675.500]
- Otorhinolaryngologic Neoplasms [C09.647]
- Neuroma, Acoustic [C09.647.675]
- Neurofibromatosis 2 [C09.647.675.500]
- Nervous System Diseases [C10]
- Cranial Nerve Diseases [C10.292]
- Cranial Nerve Neoplasms [C10.292.225]
- Neuroma, Acoustic [C10.292.225.750]
- Neurofibromatosis 2 [C10.292.225.750.500]
- Vestibulocochlear Nerve Diseases [C10.292.910]
- Neuroma, Acoustic [C10.292.910.600]
- Neurofibromatosis 2 [C10.292.910.600.500]
- Neurocutaneous Syndromes [C10.562]
- Neurofibromatoses [C10.562.600]
- Neurofibromatosis 2 [C10.562.600.750]
- Neurodegenerative Diseases [C10.574]
- Heredodegenerative Disorders, Nervous System [C10.574.500]
- Neurofibromatoses [C10.574.500.549]
- Neurofibromatosis 2 [C10.574.500.549.700]
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
- Heredodegenerative Disorders, Nervous System [C16.320.400]
- Neurofibromatoses [C16.320.400.560]
- Neurofibromatosis 2 [C16.320.400.560.700]
- Neoplastic Syndromes, Hereditary [C16.320.700]
- Neurofibromatoses [C16.320.700.645]
- Neurofibromatosis 2 [C16.320.700.645.655]
Below are MeSH descriptors whose meaning is more specific than "Neurofibromatosis 2".
This graph shows the total number of publications written about "Neurofibromatosis 2" by people in this website by year, and whether "Neurofibromatosis 2" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 2 | 1 | 3 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2014 | 2 | 0 | 2 |
| 2016 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Neurofibromatosis 2" by people in Profiles.
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Montgomery BK, Alimchandani M, Mehta GU, Dewan R, Nesvick CL, Miettinen M, Heiss JD, Asthagiri AR, Quezado M, Germanwala AV. Tumors displaying hybrid schwannoma and neurofibroma features in patients with neurofibromatosis type 2. Clin Neuropathol. 2016 Mar-Apr; 35(2):78-83.
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Firestone BK, Arias JD, Shields CL, Shields JA. Bilateral Combined Hamartomas of the Retina and Retinal Pigment Epithelium as the Presenting Feature of Neurofibromatosis Type 2 (Wishart Type). J Pediatr Ophthalmol Strabismus. 2014 May 28; 51 Online:e33-6.
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Firestone BK, Arias JD, Shields CL, Shields JA. Bilateral combined hamartomas of the retina and retinal pigment epithelium as the presenting feature of neurofibromatosis type 2 (Wishart Type). J Pediatr Ophthalmol Strabismus. 2014; 51 Online:doi: 10.3928/01913913-20140521-02.
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Lasota J, Wasag B, Dansonka-Mieszkowska A, Karcz D, Millward CL, Rys J, Stachura J, Sobin LH, Miettinen M. Evaluation of NF2 and NF1 tumor suppressor genes in distinctive gastrointestinal nerve sheath tumors traditionally diagnosed as benign schwannomas: s study of 20 cases. Lab Invest. 2003 Sep; 83(9):1361-71.
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Shields JA, Shields CL, Lavrich J. Melanocytoma of optic disk in a patient with neurofibromatosis 2. Retina. 2002 Apr; 22(2):222-3.
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Andrews DW, Suarez O, Goldman HW, Downes MB, Bednarz G, Corn BW, Werner-Wasik M, Rosenstock J, Curran WJ. Stereotactic radiosurgery and fractionated stereotactic radiotherapy for the treatment of acoustic schwannomas: comparative observations of 125 patients treated at one institution. Int J Radiat Oncol Biol Phys. 2001 Aug 01; 50(5):1265-78.
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Lasota J, Fetsch JF, Wozniak A, Wasag B, Sciot R, Miettinen M. The neurofibromatosis type 2 gene is mutated in perineurial cell tumors: a molecular genetic study of eight cases. Am J Pathol. 2001 Apr; 158(4):1223-9.
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Evans JJ, Jeun SS, Lee JH, Harwalkar JA, Shoshan Y, Cowell JK, Golubic M. Molecular alterations in the neurofibromatosis type 2 gene and its protein rarely occurring in meningothelial meningiomas. J Neurosurg. 2001 Jan; 94(1):111-7.
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Sivalingam A, Augsburger J, Perilongo G, Zimmerman R, Barabas G. Combined hamartoma of the retina and retinal pigment epithelium in a patient with neurofibromatosis type 2. J Pediatr Ophthalmol Strabismus. 1991 Nov-Dec; 28(6):320-2.