"Loratadine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria. Unlike most classical antihistamines (HISTAMINE H1 ANTAGONISTS) it lacks central nervous system depressing effects such as drowsiness.
| Descriptor ID |
D017336
|
| MeSH Number(s) |
D02.455.426.559.847.181.384.340.500 D03.383.621.160.500 D04.615.181.384.340.500
|
| Concept/Terms |
Loratadine- Loratadine
- 4-(8-Chloro-5,6-dihydro-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-1-piperidinecarboxylic Acid Ethyl Ester
|
Below are MeSH descriptors whose meaning is more general than "Loratadine".
Below are MeSH descriptors whose meaning is more specific than "Loratadine".
This graph shows the total number of publications written about "Loratadine" by people in this website by year, and whether "Loratadine" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
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Below are the most recent publications written about "Loratadine" by people in Profiles.
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Hey JA, Affrime M, Cobert B, Kreutner W, Cuss FM. Cardiovascular profile of loratadine. Clin Exp Allergy. 1999 Jul; 29 Suppl 3:197-9.
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Gawchik SM, Lim J. Comparison of intranasal triamcinolone acetonide with oral loratadine in the treatment of seasonal ragweed-induced allergic rhinitis. Am J Manag Care. 1997 Jul; 3(7):1052-8.
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Hey JA, Del Prado M, Cuss FM, Egan RW, Sherwood J, Lin CC, Kreutner W. Antihistamine activity, central nervous system and cardiovascular profiles of histamine H1 antagonists: comparative studies with loratadine, terfenadine and sedating antihistamines in guinea-pigs. Clin Exp Allergy. 1995 Oct; 25(10):974-84.
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Bronsky E, Boggs P, Findlay S, Gawchik S, Georgitis J, Mansmann H, Sholler L, Wolfe J, Meltzer E, Morris R, et al. Comparative efficacy and safety of a once-daily loratadine-pseudoephedrine combination versus its components alone and placebo in the management of seasonal allergic rhinitis. J Allergy Clin Immunol. 1995 Aug; 96(2):139-47.
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Ciprandi G, Buscaglia S, Marchesi E, Danzig M, Cuss F, Canonica GW. Protective effect of loratadine on late phase reaction induced by conjunctival provocation test. Int Arch Allergy Immunol. 1993; 100(2):185-9.
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Monroe EW, Bernstein DI, Fox RW, Grabiec SV, Honsinger RW, Kalivas JT, Katz HI, Cuss F, Danzig MR, Garvin PR, et al. Relative efficacy and safety of loratadine, hydroxyzine, and placebo in chronic idiopathic urticaria. Arzneimittelforschung. 1992 Sep; 42(9):1119-21.