Reactive Oxygen Species

"Reactive Oxygen Species" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Molecules or ions formed by the incomplete one-electron reduction of oxygen. These reactive oxygen intermediates include SINGLET OXYGEN; SUPEROXIDES; PEROXIDES; HYDROXYL RADICAL; and HYPOCHLOROUS ACID. They contribute to the microbicidal activity of PHAGOCYTES, regulation of SIGNAL TRANSDUCTION and GENE EXPRESSION, and the oxidative damage to NUCLEIC ACIDS; PROTEINS; and LIPIDS.

Descriptor ID	D017382
MeSH Number(s)	D01.339.431 D01.650.775
Concept/Terms	Reactive Oxygen Species Reactive Oxygen Species Oxygen Species, Reactive Active Oxygen Oxygen, Active Oxygen Radicals Pro-Oxidants Pro Oxidants

Below are MeSH descriptors whose meaning is more general than "Reactive Oxygen Species".

Chemicals and Drugs [D]
Inorganic Chemicals [D01]
Free Radicals [D01.339]
Reactive Oxygen Species [D01.339.431]
Oxygen Compounds [D01.650]
Reactive Oxygen Species [D01.650.775]

Below are MeSH descriptors whose meaning is related to "Reactive Oxygen Species".

Below are MeSH descriptors whose meaning is more specific than "Reactive Oxygen Species".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Reactive Oxygen Species" by people in this website by year, and whether "Reactive Oxygen Species" was a major or minor topic of these publications.

Bar chart showing 239 publications over 30 distinct years, with a maximum of 20 publications in 2012 and 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	2	2	4
1997	0	1	1
1998	0	1	1
1999	0	2	2
2000	0	1	1
2001	0	2	2
2002	1	5	6
2003	3	8	11
2004	2	3	5
2005	1	6	7
2006	0	2	2
2007	1	6	7
2008	2	4	6
2009	3	4	7
2010	3	9	12
2011	4	5	9
2012	2	18	20
2013	4	16	20
2014	4	15	19
2015	3	13	16
2016	3	12	15
2017	5	9	14
2018	2	9	11
2019	0	9	9
2020	2	5	7
2021	2	6	8
2022	0	3	3
2023	0	9	9
2024	1	3	4
2025	0	1	1

Below are the most recent publications written about "Reactive Oxygen Species" by people in Profiles.

Islam R, Roche ME, Lin Z, Whitaker-Menezes D, Diaz-Barros V, Serrano E, Martinez Cantarin MP, Philp NJ, Basu Mallick A, Martinez-Outschoorn U. TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis. Mol Oncol. 2025 Aug; 19(8):2431-2455.

View in: PubMed
Mondal A, Das B, Karmakar S, Pani S, Khan S, Gupta P, Das Sarma J. Modulatory Role of Pantropic Cell Signaling Pathways in the Antimigratory and Antiproliferative Action of Triazole Chelated Iridium(III) Complexes in Cervical Cancer Cells. J Med Chem. 2024 11 28; 67(22):20559-20570.

View in: PubMed
Nedo AO, Liang H, Sriram J, Razzak MA, Lee JY, Kambhamettu C, Dinesh-Kumar SP, Caplan JL. CHUP1 restricts chloroplast movement and effector-triggered immunity in epidermal cells. New Phytol. 2024 12; 244(5):1864-1881.

View in: PubMed
Zarei M, Hajihassani O, Hue JJ, Loftus AW, Graor HJ, Nakazzi F, Naji P, Boutros CS, Uppin V, Vaziri-Gohar A, Shalaby AS, Asara JM, Rothermel LD, Brody JR, Winter JM. IDH1 Inhibition Potentiates Chemotherapy Efficacy in Pancreatic Cancer. Cancer Res. 2024 09 16; 84(18):3072-3085.

View in: PubMed
Brailoiu E, Barr JL, Wittorf HN, Inan S, Unterwald EM, Brailoiu GC. Modulation of the Blood-Brain Barrier by Sigma-1R Activation. Int J Mol Sci. 2024 May 09; 25(10).

View in: PubMed
DiMartini ET, Kyker-Snowman K, Shreiber DI. A click chemistry-based, free radical-initiated delivery system for the capture and release of payloads. Drug Deliv. 2023 Dec; 30(1):2232952.

View in: PubMed
Deshpande DA, Penn RB. Reactive Oxygen Species Behaving Badly: Oxidized Phosphatidylcholines Corrupt Ca2+ Signaling in Airway Smooth Muscle. Am J Respir Cell Mol Biol. 2023 12; 69(6):605-607.

View in: PubMed
Ramos Gonzalez M, Axler MR, Kaseman KE, Lobene AJ, Farquhar WB, Witman MA, Kirkman DL, Lennon SL. Melatonin supplementation does not alter vascular function or oxidative stress in healthy normotensive adults on a high sodium diet. Physiol Rep. 2023 12; 11(24):e15896.

View in: PubMed
Smit RD, Ghosh B, Campion TJ, Stingel R, Lavell E, Hooper R, Fan X, Soboloff J, Smith GM. STAT3 protects dopaminergic neurons against degeneration in animal model of Parkinson's disease. Brain Res. 2024 02 01; 1824:148691.

View in: PubMed
Oyer HM, Steck AR, Longen CG, Venkat S, Bayrak K, Munger EB, Fu D, Castagnino PA, Sanders CM, Tancler NA, Mai MT, Myers JP, Schiewer MJ, Chen N, Mostaghel EA, Kim FJ. Sigma1 Regulates Lipid Droplet-mediated Redox Homeostasis Required for Prostate Cancer Proliferation. Cancer Res Commun. 2023 10 30; 3(10):2195-2210.

View in: PubMed

People

Explore

Similar Concepts

Top Journals

The Thomas Jefferson University web site, its contents and programs, is provided for informational and educational purposes only and is not intended as medical advice nor is it intended to create any physician-patient relationship. Please remember that this information should not substitute for a visit or a consultation with a health care provider. The views or opinions expressed in the resources provided do not necessarily reflect those of Thomas Jefferson University, Thomas Jefferson University Hospital, or the Jefferson Health System or staff.
Please read our Privacy Statement