Receptors, Transforming Growth Factor beta

"Receptors, Transforming Growth Factor beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Cell-surface proteins that bind transforming growth factor beta and trigger changes influencing the behavior of cells. Two types of transforming growth factor receptors have been recognized. They differ in affinity for different members of the transforming growth factor beta family and in cellular mechanisms of action.

Descriptor ID	D018125
MeSH Number(s)	D12.776.543.750.705.852.720 D12.776.543.750.750.400.820
Concept/Terms	Receptors, Transforming Growth Factor beta Receptors, Transforming Growth Factor beta Transforming Growth Factor beta Receptors Receptors, TGF-beta Receptors, TGF beta TGF-beta Receptor Receptor, TGF-beta TGF beta Receptor TGF-beta Receptors TGF beta Receptors Transforming Growth Factor beta Receptor

Below are MeSH descriptors whose meaning is more general than "Receptors, Transforming Growth Factor beta".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, Immunologic [D12.776.543.750.705]
Receptors, Cytokine [D12.776.543.750.705.852]
Receptors, Transforming Growth Factor beta [D12.776.543.750.705.852.720]
Receptors, Peptide [D12.776.543.750.750]
Receptors, Growth Factor [D12.776.543.750.750.400]
Receptors, Transforming Growth Factor beta [D12.776.543.750.750.400.820]

Below are MeSH descriptors whose meaning is more specific than "Receptors, Transforming Growth Factor beta".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptors, Transforming Growth Factor beta" by people in this website by year, and whether "Receptors, Transforming Growth Factor beta" was a major or minor topic of these publications.

Bar chart showing 40 publications over 21 distinct years, with a maximum of 4 publications in 2012 and 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
1998	2	0	2
2001	1	1	2
2002	1	0	1
2003	1	1	2
2004	0	1	1
2005	0	1	1
2006	3	0	3
2007	0	1	1
2008	3	0	3
2009	0	1	1
2010	2	1	3
2011	0	1	1
2012	0	4	4
2013	0	3	3
2014	2	0	2
2015	2	2	4
2017	0	1	1
2018	0	2	2
2019	1	0	1
2024	0	1	1

Below are the most recent publications written about "Receptors, Transforming Growth Factor beta" by people in Profiles.

Shimonosono M, Morimoto M, Hirose W, Tomita Y, Matsuura N, Flashner S, Ebadi MS, Okayasu EH, Lee CY, Britton WR, Martin C, Wuertz BR, Parikh AS, Sachdeva UM, Ondrey FG, Atigadda VR, Elmets CA, Abrams JA, Muir AB, Klein-Szanto AJ, Weinberg KI, Momen-Heravi F, Nakagawa H. Modeling Epithelial Homeostasis and Perturbation in Three-Dimensional Human Esophageal Organoids. Biomolecules. 2024 09 05; 14(9).

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Kelley RK, Gane E, Assenat E, Siebler J, Galle PR, Merle P, Hourmand IO, Cleverly A, Zhao Y, Gueorguieva I, Lahn M, Faivre S, Benhadji KA, Giannelli G. A Phase 2 Study of Galunisertib (TGF-?1 Receptor Type I Inhibitor) and Sorafenib in Patients With Advanced Hepatocellular Carcinoma. Clin Transl Gastroenterol. 2019 07; 10(7):e00056.

View in: PubMed
Wermuth PJ, Jimenez SA. Abrogation of transforming growth factor-?-induced tissue fibrosis in TBRIcaCol1a2Cre transgenic mice by the second generation tyrosine kinase inhibitor SKI-606 (Bosutinib). PLoS One. 2018; 13(5):e0196559.

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Akpan I, Pro B, Platanias LC. Transforming growth factor superfamily ligands and links to tumorigenesis. Leuk Lymphoma. 2018 06; 59(6):1282-1283.

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Rawal S, Munasinghe PE, Nagesh PT, Lew JKS, Jones GT, Williams MJA, Davis P, Bunton D, Galvin IF, Manning P, Lamberts RR, Katare R. Down-regulation of miR-15a/b accelerates fibrotic remodelling in the Type?2 diabetic human and mouse heart. Clin Sci (Lond). 2017 May 01; 131(9):847-863.

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Miles FL, Kurtoglu S, Ahmer C, Soori M, Favate JS, Sikes RA. Transforming growth factor-? signaling induced during prostate cancer cell death and neuroendocrine differentiation is mediated by bone marrow stromal cells. Prostate. 2015 Nov; 75(15):1802-13.

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Dewan AK, Tomlinson RE, Mitchell S, Goh BC, Yung RM, Kumar S, Tan EW, Faugere MC, Dietz HC, Clemens TL, Sponseller PD. Dysregulated TGF-? signaling alters bone microstructure in a mouse model of Loeys-Dietz syndrome. J Orthop Res. 2015 Oct; 33(10):1447-54.

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Nallet-Staub F, Yin X, Gilbert C, Marsaud V, Ben Mimoun S, Javelaud D, Leof EB, Mauviel A. Cell density sensing alters TGF-? signaling in a cell-type-specific manner, independent from Hippo pathway activation. Dev Cell. 2015 Mar 09; 32(5):640-51.

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Paloschi V, G?din JR, Khan S, Bj?rck HM, Du L, Maleki S, Roy J, Lindeman JH, Mohamed SA, Tsuda T, Franco-Cereceda A, Eriksson P. Aneurysm development in patients with a bicuspid aortic valve is not associated with transforming growth factor-? activation. Arterioscler Thromb Vasc Biol. 2015 Apr; 35(4):973-80.

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Barthold JS, Wang Y, Kolon TF, Kollin C, Nordenskj?ld A, Olivant Fisher A, Figueroa TE, BaniHani AH, Hagerty JA, Gonzalez R, Noh PH, Chiavacci RM, Harden KR, Abrams DJ, Kim CE, Mateson AB, Robbins AK, Li J, Akins RE, Hakonarson H, Devoto M. Phenotype specific association of the TGFBR3 locus with nonsyndromic cryptorchidism. J Urol. 2015 May; 193(5):1637-45.

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