Neuroectodermal Tumors, Primitive

"Neuroectodermal Tumors, Primitive" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A group of malignant tumors of the nervous system that feature primitive cells with elements of neuronal and/or glial differentiation. Use of this term is limited by some authors to central nervous system tumors and others include neoplasms of similar origin which arise extracranially (i.e., NEUROECTODERMAL TUMORS, PRIMITIVE, PERIPHERAL). This term is also occasionally used as a synonym for MEDULLOBLASTOMA. In general, these tumors arise in the first decade of life and tend to be highly malignant. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2059)

Descriptor ID	D018242
MeSH Number(s)	C04.557.465.625.600.590 C04.557.470.670.590 C04.557.580.625.600.590
Concept/Terms	Neuroectodermal Tumors, Primitive Neuroectodermal Tumors, Primitive Neuroectodermal Tumor, Primitive Primitive Neuroectodermal Tumor Primitive Neuroectodermal Tumors Tumor, Primitive Neuroectodermal Tumors, Primitive Neuroectodermal Primitive Neuroepithelial Neoplasms Neuroepithelial Tumors, Primitive Neuroepithelial Tumor, Primitive Primitive Neuroepithelial Tumor Primitive Neuroepithelial Tumors Tumor, Primitive Neuroepithelial Tumors, Primitive Neuroepithelial PNET PNETs Neoplasms, Primitive Neuroepithelial Neoplasm, Primitive Neuroepithelial Neuroepithelial Neoplasm, Primitive Primitive Neuroepithelial Neoplasm Neuroepithelial Neoplasms, Primitive Medulloepithelioma Medulloepithelioma Medulloepitheliomas Cerebral Primitive Neuroectodermal Tumor Cerebral Primitive Neuroectodermal Tumor Ependymoblastoma Ependymoblastoma Ependymoblastomas Spongioblastoma Spongioblastoma Spongioblastomas

Below are MeSH descriptors whose meaning is more general than "Neuroectodermal Tumors, Primitive".

Diseases [C]
Neoplasms [C04]
Neoplasms by Histologic Type [C04.557]
Neoplasms, Germ Cell and Embryonal [C04.557.465]
Neuroectodermal Tumors [C04.557.465.625]
Neoplasms, Neuroepithelial [C04.557.465.625.600]
Neuroectodermal Tumors, Primitive [C04.557.465.625.600.590]
Neoplasms, Glandular and Epithelial [C04.557.470]
Neoplasms, Neuroepithelial [C04.557.470.670]
Neuroectodermal Tumors, Primitive [C04.557.470.670.590]
Neoplasms, Nerve Tissue [C04.557.580]
Neuroectodermal Tumors [C04.557.580.625]
Neoplasms, Neuroepithelial [C04.557.580.625.600]
Neuroectodermal Tumors, Primitive [C04.557.580.625.600.590]

Below are MeSH descriptors whose meaning is related to "Neuroectodermal Tumors, Primitive".

Below are MeSH descriptors whose meaning is more specific than "Neuroectodermal Tumors, Primitive".

Neuroectodermal Tumors, Primitive
Medulloblastoma
Neuroectodermal Tumors, Primitive, Peripheral

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Neuroectodermal Tumors, Primitive" by people in this website by year, and whether "Neuroectodermal Tumors, Primitive" was a major or minor topic of these publications.

Bar chart showing 21 publications over 13 distinct years, with a maximum of 4 publications in 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	2	0	2
2005	1	0	1
2006	1	0	1
2007	1	0	1
2010	1	0	1
2011	1	0	1
2013	3	0	3
2014	1	1	2
2015	4	0	4
2016	1	0	1
2018	1	0	1
2019	2	0	2
2025	1	0	1

Below are the most recent publications written about "Neuroectodermal Tumors, Primitive" by people in Profiles.

August AH, Cernichiaro-Espinosa LA, Moctezuma-Davila M, Wibbelsman TD, Wilson MW, Ch?vez-Barrios P, Shields CL, Lally SE, Eberhart CG, Orr BA, Simpson E, Eagle RC, Milman T. Ciliary Body Medulloepithelioma: Clinical and Pathologic Challenges with a Focus on Molecular Genetics. Semin Ophthalmol. 2025 Aug; 40(6):518-528.

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Tadepalli SH, Shields CL, Shields JA, Honavar SG. Intraocular medulloepithelioma - A review of clinical features, DICER 1 mutation, and management. Indian J Ophthalmol. 2019 06; 67(6):755-762.

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Scott NL, Tran KD, Cernichiaro-Espinosa LA, Russell JF, Hinkle JW, Harbour JW, Dubovy SR, Berrocal AM. An Eight-Year-Old Girl Presents With Two Weeks of Vision Loss and Nightly Headaches. Ophthalmic Surg Lasers Imaging Retina. 2019 05 01; 50(5):314-317.

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Ang SM, Dalvin LA, Emrich J, Komarnicky L, Shields JA, Shields CL. Plaque Radiotherapy for Medulloepithelioma in 6 Cases From a Single Center. Asia Pac J Ophthalmol (Phila). 2019 Jan-Feb; 8(1):30-35.

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Avedschmidt SE, Stagner AM, Eagle RC, Harocopos GJ, Dou Y, Rao RC. The Targetable Epigenetic Tumor Protein EZH2 is Enriched in Intraocular Medulloepithelioma. Invest Ophthalmol Vis Sci. 2016 11 01; 57(14):6242-6246.

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Korshunov A, Jakobiec FA, Eberhart CG, Hovestadt V, Capper D, Jones DT, Sturm D, Stagner AM, Edward DP, Eagle RC, Proia AD, Koch A, Ryzhova M, Ektova A, Sch?ller U, Zheludkova O, Lichter P, von Deimling A, Pfister SM, Kool M. Comparative integrated molecular analysis of intraocular medulloepitheliomas and central nervous system embryonal tumors with multilayered rosettes confirms that they are distinct nosologic entities. Neuropathology. 2015 Dec; 35(6):538-44.

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Shields JA, Eagle RC, Ferguson K, Shields CL. TUMORS OF THE NONPIGMENTED EPITHELIUM OF THE CILIARY BODY: The Lorenz E. Zimmerman Tribute Lecture. Retina. 2015 May; 35(5):957-65.

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Vu LT, Keschrumrus V, Zhang X, Zhong JF, Su Q, Kabeer MH, Loudon WG, Li SC. Tissue elasticity regulated tumor gene expression: implication for diagnostic biomarkers of primitive neuroectodermal tumor. PLoS One. 2015; 10(3):e0120336.

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Jakobiec FA, Kool M, Stagner AM, Pfister SM, Eagle RC, Proia AD, Korshunov A. Intraocular Medulloepitheliomas and Embryonal Tumors With Multilayered Rosettes of the Brain: Comparative Roles of LIN28A and C19MC. Am J Ophthalmol. 2015 Jun; 159(6):1065-1074.e1.

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Barakat LP, Li Y, Hobbie WL, Ogle SK, Hardie T, Volpe EM, Szabo MM, Reilly M, Deatrick JA. Health-related quality of life of adolescent and young adult survivors of childhood brain tumors. Psychooncology. 2015 Jul; 24(7):804-11.

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