Receptors, Adrenergic, beta-1
"Receptors, Adrenergic, beta-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of beta-adrenergic receptors (RECEPTORS, ADRENERGIC, BETA). The adrenergic beta-1 receptors are equally sensitive to EPINEPHRINE and NOREPINEPHRINE and bind the agonist DOBUTAMINE and the antagonist METOPROLOL with high affinity. They are found in the HEART, juxtaglomerular cells, and in the central and peripheral nervous systems.
| Descriptor ID |
D018342
|
| MeSH Number(s) |
D12.776.543.750.670.300.300.340.100 D12.776.543.750.695.150.300.340.700 D12.776.543.750.720.330.300.340.100
|
| Concept/Terms |
Receptors, Adrenergic, beta-1- Receptors, Adrenergic, beta-1
- Receptor, Adrenergic, beta-1
- Receptors, beta-1 Adrenergic
- Receptors, beta 1 Adrenergic
- beta-1 Adrenergic Receptors
- Adrenergic Receptors, beta-1
- beta 1 Adrenergic Receptors
- Adrenergic beta-1 Receptors
- Adrenergic beta 1 Receptors
- Receptors, Adrenergic beta-1
- beta-1 Receptors, Adrenergic
- Adrenergic Receptor, beta-1
- Adrenergic Receptor, beta 1
- Receptor, beta-1 Adrenergic
- beta-1 Adrenergic Receptor
- beta 1 Adrenergic Receptor
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Adrenergic, beta-1".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.670]
- Receptors, Catecholamine [D12.776.543.750.670.300]
- Receptors, Adrenergic [D12.776.543.750.670.300.300]
- Receptors, Adrenergic, beta [D12.776.543.750.670.300.300.340]
- Receptors, Adrenergic, beta-1 [D12.776.543.750.670.300.300.340.100]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Catecholamine [D12.776.543.750.695.150]
- Receptors, Adrenergic [D12.776.543.750.695.150.300]
- Receptors, Adrenergic, beta [D12.776.543.750.695.150.300.340]
- Receptors, Adrenergic, beta-1 [D12.776.543.750.695.150.300.340.700]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Catecholamine [D12.776.543.750.720.330]
- Receptors, Adrenergic [D12.776.543.750.720.330.300]
- Receptors, Adrenergic, beta [D12.776.543.750.720.330.300.340]
- Receptors, Adrenergic, beta-1 [D12.776.543.750.720.330.300.340.100]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Adrenergic, beta-1".
This graph shows the total number of publications written about "Receptors, Adrenergic, beta-1" by people in this website by year, and whether "Receptors, Adrenergic, beta-1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 2 | 2 | 4 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Receptors, Adrenergic, beta-1" by people in Profiles.
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Yoo SM, Bhardwaj A, Benovic JL. Arresting Developments in Biased Signaling. Trends Pharmacol Sci. 2020 06; 41(6):387-389.
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O-Uchi J, Komukai K, Kusakari Y, Morimoto S, Kawai M, Jhun BS, Hurst S, Hongo K, Sheu SS, Kurihara S. Alpha1-adrenenoceptor stimulation inhibits cardiac excitation-contraction coupling through tyrosine phosphorylation of beta1-adrenoceptor. Biochem Biophys Res Commun. 2013 Apr 05; 433(2):188-93.
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Seqqat R, Guo X, Rafiq K, Kolpakov MA, Guo J, Koch WJ, Houser SR, Dell'italia LJ, Sabri A. Beta1-adrenergic receptors promote focal adhesion signaling downregulation and myocyte apoptosis in acute volume overload. J Mol Cell Cardiol. 2012 Aug; 53(2):240-9.
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Fain JN, Cheema P, Tichansky DS, Madan AK. Stimulation of human omental adipose tissue lipolysis by growth hormone plus dexamethasone. Mol Cell Endocrinol. 2008 Nov 25; 295(1-2):101-5.
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Medei EH, Nascimento JH, Pedrosa RC, Barcellos L, Masuda MO, Sicouri S, Elizari MV, de Carvalho AC. Antibodies with beta-adrenergic activity from chronic chagasic patients modulate the QT interval and M cell action potential duration. Europace. 2008 Jul; 10(7):868-76.
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Sabri A, Rafiq K, Seqqat R, Kolpakov MA, Dillon R, Dell'italia LJ. Sympathetic activation causes focal adhesion signaling alteration in early compensated volume overload attributable to isolated mitral regurgitation in the dog. Circ Res. 2008 May 09; 102(9):1127-36.
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Young CN, Prasad RY, Fullenkamp AM, Stillbower ME, Farquhar WB, Edwards DG. Ultrasound assessment of popliteal vein compliance during a short deflation protocol. J Appl Physiol (1985). 2008 May; 104(5):1374-80.
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Gavi S, Yin D, Shumay E, Wang HY, Malbon CC. Insulin-like growth factor-I provokes functional antagonism and internalization of beta1-adrenergic receptors. Endocrinology. 2007 Jun; 148(6):2653-62.
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Keys JR, Zhou RH, Harris DM, Druckman CA, Eckhart AD. Vascular smooth muscle overexpression of G protein-coupled receptor kinase 5 elevates blood pressure, which segregates with sex and is dependent on Gi-mediated signaling. Circulation. 2005 Aug 23; 112(8):1145-53.
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Gavi S, Yin D, Shumay E, Wang HY, Malbon CC. The 15-amino acid motif of the C terminus of the beta2-adrenergic receptor is sufficient to confer insulin-stimulated counterregulation to the beta1-adrenergic receptor. Endocrinology. 2005 Jan; 146(1):450-7.