Mucin-1

"Mucin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Carbohydrate antigen elevated in patients with tumors of the breast, ovary, lung, and prostate as well as other disorders. The mucin is expressed normally by most glandular epithelia but shows particularly increased expression in the breast at lactation and in malignancy. It is thus an established serum marker for breast cancer.

Descriptor ID	D018396
MeSH Number(s)	D12.776.395.550.560 D12.776.395.560.631.115 D12.776.543.550.530 D23.050.285.050.300 D23.050.550.325.300 D23.101.140.075.300
Concept/Terms	Mucin-1 Mucin-1 Mucin 1 CA 15.3 Antigen Antigen, CA 15.3 Antigen CA-15-3 Antigen CA 15 3 CA-15-3, Antigen CA-15-3 Antigen Antigen, CA-15-3 Episialin CD227 Antigen Antigen, CD227 Polymorphic Epithelial Mucin Epithelial Membrane Antigen Antigen, Epithelial Membrane Membrane Antigen, Epithelial Muc1 Mucin Mucin, Muc1 Antigens, CD227 CD227 Antigens CA 15-3 Antigen Antigen, CA 15-3 CA 15 3 Antigen Epithelial Mucin, Polymorphic Mucin, Polymorphic Epithelial

Below are MeSH descriptors whose meaning is more general than "Mucin-1".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Glycoproteins [D12.776.395]
Membrane Glycoproteins [D12.776.395.550]
Mucin-1 [D12.776.395.550.560]
Mucoproteins [D12.776.395.560]
Mucins [D12.776.395.560.631]
Mucin-1 [D12.776.395.560.631.115]
Membrane Proteins [D12.776.543]
Membrane Glycoproteins [D12.776.543.550]
Mucin-1 [D12.776.543.550.530]
Biological Factors [D23]
Antigens [D23.050]
Antigens, Neoplasm [D23.050.285]
Antigens, Tumor-Associated, Carbohydrate [D23.050.285.050]
Mucin-1 [D23.050.285.050.300]
Epitopes [D23.050.550]
Antigens, Tumor-Associated, Carbohydrate [D23.050.550.325]
Mucin-1 [D23.050.550.325.300]
Biomarkers [D23.101]
Biomarkers, Tumor [D23.101.140]
Antigens, Tumor-Associated, Carbohydrate [D23.101.140.075]
Mucin-1 [D23.101.140.075.300]

Below are MeSH descriptors whose meaning is related to "Mucin-1".

Below are MeSH descriptors whose meaning is more specific than "Mucin-1".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Mucin-1" by people in this website by year, and whether "Mucin-1" was a major or minor topic of these publications.

Bar chart showing 20 publications over 17 distinct years, with a maximum of 2 publications in 2001 and 2004 and 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
1998	0	1	1
1999	0	1	1
2000	0	1	1
2001	0	2	2
2002	0	1	1
2004	2	0	2
2006	0	1	1
2007	0	1	1
2008	0	1	1
2013	1	0	1
2014	1	1	2
2016	0	1	1
2017	1	0	1
2018	0	1	1
2019	1	0	1
2022	1	0	1

Below are the most recent publications written about "Mucin-1" by people in Profiles.

Wu D, Chapela PJ, Barrows CML, Harrington DA, Carson DD, Witt RL, Mohyuddin NG, Pradhan-Bhatt S, Farach-Carson MC. MUC1 and Polarity Markers INADL and SCRIB Identify Salivary Ductal Cells. J Dent Res. 2022 07; 101(8):983-991.

View in: PubMed
Khalili M, Zhou H, Thadi A, Daniels L, Fan Z, Morano WF, Ang J, Goldstein E, Polyak B, Mapow BC, Cheng H, Bowne WB. Slippery Nanoparticles as a Diffusion Platform for Mucin Producing Gastrointestinal Tumors. Ann Surg Oncol. 2020 Jan; 27(1):76-84.

View in: PubMed
Perepelyuk M, Sacko K, Thangavel K, Shoyele SA. Evaluation of MUC1-Aptamer Functionalized Hybrid Nanoparticles for Targeted Delivery of miRNA-29b to Nonsmall Cell Lung Cancer. Mol Pharm. 2018 03 05; 15(3):985-993.

View in: PubMed
Kato K, Zemskova MA, Hanss AD, Kim MM, Summer R, Kim KC. Muc1 deficiency exacerbates pulmonary fibrosis in a mouse model of silicosis. Biochem Biophys Res Commun. 2017 11 25; 493(3):1230-1235.

View in: PubMed
Perepelyuk M, Maher C, Lakshmikuttyamma A, Shoyele SA. Aptamer-hybrid nanoparticle bioconjugate efficiently delivers miRNA-29b to non-small-cell lung cancer cells and inhibits growth by downregulating essential oncoproteins. Int J Nanomedicine. 2016; 11:3533-44.

View in: PubMed
Lee KM, Nam K, Oh S, Lim J, Kim YP, Lee JW, Yu JH, Ahn SH, Kim SB, Noh DY, Lee T, Shin I. Extracellular matrix protein 1 regulates cell proliferation and trastuzumab resistance through activation of epidermal growth factor signaling. Breast Cancer Res. 2014 Dec 11; 16(6):479.

View in: PubMed
Tholey RM, Lal S, Jimbo M, Burkhart RA, Blanco FF, Cozzitorto JA, Eisenberg JD, Jiang W, Iacobuzio-Donahue CA, Witkiewicz AK, Glbert M, Yeo CJ, Brody JR, Sawicki JA, Winter JM. MUC1 Promoter-Driven DTA as a Targeted Therapeutic Strategy against Pancreatic Cancer. Mol Cancer Res. 2015 Mar; 13(3):439-48.

View in: PubMed
Cristofanilli M, Fortina P. Circulating tumor DNA to monitor metastatic breast cancer. N Engl J Med. 2013 07 04; 369(1):93.

View in: PubMed
Al-Daraji WI, Miettinen M. Superficial acral fibromyxoma: a clinicopathological analysis of 32 tumors including 4 in the heel. J Cutan Pathol. 2008 Nov; 35(11):1020-6.

View in: PubMed
Chandramouly G, Abad PC, Knowles DW, Leli?vre SA. The control of tissue architecture over nuclear organization is crucial for epithelial cell fate. J Cell Sci. 2007 May 01; 120(Pt 9):1596-606.

View in: PubMed

People

Explore

Similar Concepts

Top Journals

The Thomas Jefferson University web site, its contents and programs, is provided for informational and educational purposes only and is not intended as medical advice nor is it intended to create any physician-patient relationship. Please remember that this information should not substitute for a visit or a consultation with a health care provider. The views or opinions expressed in the resources provided do not necessarily reflect those of Thomas Jefferson University, Thomas Jefferson University Hospital, or the Jefferson Health System or staff.
Please read our Privacy Statement