Genes, erbB-1

"Genes, erbB-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The proto-oncogene c-erbB-1 codes for the epidermal growth factor receptor. Its name originates from the viral homolog v-erbB which was isolated from an avian erythroblastosis virus (AEV) where it was contained as a fragment of the chicken c-ErbB-1 gene lacking the amino-terminal ligand-binding domain. Overexpression of erbB-1 genes occurs in a wide range of tumors, commonly squamous carcinomas of various sites and less commonly adenocarcinomas. The human c-erbB-1 gene is located in the chromosomal region 7p14 and 7p12.

Descriptor ID	D018773
MeSH Number(s)	G05.360.340.024.340.375.500.791.295.300
Concept/Terms	Genes, erbB-1 Genes, erbB-1 Genes, erbB1 Gene, erbB1 erbB1 Gene erbB1 Genes erbB-1 Genes erbB 1 Genes erbB-1 Gene v-erbB Genes v-erbB Genes v erbB Genes v-erbB Gene v-erbB Oncogenes v erbB Oncogenes v-erbB Oncogene c-erbB-1 Genes c-erbB-1 Genes c erbB 1 Genes c-erbB-1 Gene EGFR Genes Epidermal Growth Factor Receptor Genes c-erbB-1 Proto-Oncogenes c erbB 1 Proto Oncogenes c-erbB-1 Proto-Oncogene Genes, EGFR EGFR Gene

Below are MeSH descriptors whose meaning is more general than "Genes, erbB-1".

Biological Sciences [G]
Genetic Phenomena [G05]
Genetic Structures [G05.360]
Genome [G05.360.340]
Genome Components [G05.360.340.024]
Genes [G05.360.340.024.340]
Genes, Neoplasm [G05.360.340.024.340.375]
Oncogenes [G05.360.340.024.340.375.500]
Proto-Oncogenes [G05.360.340.024.340.375.500.791]
Genes, erbB [G05.360.340.024.340.375.500.791.295]
Genes, erbB-1 [G05.360.340.024.340.375.500.791.295.300]

Below are MeSH descriptors whose meaning is related to "Genes, erbB-1".

Below are MeSH descriptors whose meaning is more specific than "Genes, erbB-1".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Genes, erbB-1" by people in this website by year, and whether "Genes, erbB-1" was a major or minor topic of these publications.

Bar chart showing 9 publications over 7 distinct years, with a maximum of 2 publications in 2007 and 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2007	2	0	2
2008	0	1	1
2011	0	2	2
2012	1	0	1
2015	0	1	1
2017	0	1	1
2020	0	1	1

Below are the most recent publications written about "Genes, erbB-1" by people in Profiles.

Shahbazi MN, Wang T, Tao X, Weatherbee BAT, Sun L, Zhan Y, Keller L, Smith GD, Pellicer A, Scott RT, Seli E, Zernicka-Goetz M. Developmental potential of aneuploid human embryos cultured beyond implantation. Nat Commun. 2020 08 10; 11(1):3987.

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Yang M, Topaloglu U, Petty WJ, Pagni M, Foley KL, Grant SC, Robinson M, Bitting RL, Thomas A, Alistar AT, Desnoyers RJ, Goodman M, Albright C, Porosnicu M, Vatca M, Qasem SA, DeYoung B, Kytola V, Nykter M, Chen K, Levine EA, Staren ED, D'Agostino RB, Petro RM, Blackstock W, Powell BL, Abraham E, Pasche B, Zhang W. Circulating mutational portrait of cancer: manifestation of aggressive clonal events in both early and late stages. J Hematol Oncol. 2017 05 04; 10(1):100.

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Janku F, Angenendt P, Tsimberidou AM, Fu S, Naing A, Falchook GS, Hong DS, Holley VR, Cabrilo G, Wheler JJ, Piha-Paul SA, Zinner RG, Bedikian AY, Overman MJ, Kee BK, Kim KB, Kopetz ES, Luthra R, Diehl F, Meric-Bernstam F, Kurzrock R. Actionable mutations in plasma cell-free DNA in patients with advanced cancers referred for experimental targeted therapies. Oncotarget. 2015 May 20; 6(14):12809-21.

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Leslie KK, Sill MW, Lankes HA, Fischer EG, Godwin AK, Gray H, Schilder RJ, Walker JL, Tewari K, Hanjani P, Abulafia O, Rose PG. Lapatinib and potential prognostic value of EGFR mutations in a Gynecologic Oncology Group phase II trial of persistent or recurrent endometrial cancer. Gynecol Oncol. 2012 Nov; 127(2):345-50.

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Rafiq K, Guo J, Vlasenko L, Guo X, Kolpakov MA, Sanjay A, Houser SR, Sabri A. c-Cbl ubiquitin ligase regulates focal adhesion protein turnover and myofibril degeneration induced by neutrophil protease cathepsin G. J Biol Chem. 2012 Feb 17; 287(8):5327-39.

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Belo A, Cheng K, Chahdi A, Shant J, Xie G, Khurana S, Raufman JP. Muscarinic receptor agonists stimulate human colon cancer cell migration and invasion. Am J Physiol Gastrointest Liver Physiol. 2011 May; 300(5):G749-60.

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Gibson TB, Grothey E, Chu E. Highlights from: The 44th Annual Meeting of the American Society of Clinical Oncology. Chicago, IL; May 30-June 3, 2008. Clin Colorectal Cancer. 2008 Jul; 7(4):233-9.

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Okawa T, Michaylira CZ, Kalabis J, Stairs DB, Nakagawa H, Andl CD, Johnstone CN, Klein-Szanto AJ, El-Deiry WS, Cukierman E, Herlyn M, Rustgi AK. The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and differentiation. Genes Dev. 2007 Nov 01; 21(21):2788-803.

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Yu JJ, Flynn DC. EGFR artifactual mutations associated with two DNA sequencers. Biotechniques. 2007 Jan; 42(1):41.

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